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Lipoamino acid


DATA No : ALA0003 INFORMANT : Youko Kawai

NAME : a-N-[3-(2-hydroxyisopentadecanoyloxy)isoheptadecanoyl]-ornithine

COMMON NAME: OH-type ornithine-containing lipid of Flavovacterium
SYMBOL:
FORMULA: C37H72O6N2 MOL.WT (average) : 640.977


Download ChemDraw structure data
BIOLOGICAL ACTIVITY
Macrophage activation was very weak (Ref. 0011)
PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:Ester and secondary amide linkages
[Spectrum 0007]

NMR SPECTRA:

MASS SPECTRA:
[Spectrum 0008] Molecular ion 641

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE
Flavobacterium meningosepticum (Ref. 0004)
CHEMICAL SYNTHESIS

METABOLISM

GENETIC INFORMATION

NOTE

[Chromatogram 0001](Data No. 0002)
REFERENCES
[0004]
AUTHOR:Kawai, Y., Yano, I., and Kaneda, K.
TITLE:Various kinds of lipoamino acids including a novel serine-containing lipid in an opportunistic pathogen Flavobacterium. Their structures and biological activities on erythrocytes PubMed ID:3123236
JOURNAL:Eur J Biochem.
VOL:171 PAGE : 73-80 (1988)
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[0011]
AUTHOR:Kawai, Y., Nakagawa, Y., Matuyama, T., Akagawa, K., Itagawa, K., Fukase, K., Kusumoto, S., Nishijima, M., and Yano, I.
TITLE:A typical bacterial ornithine-containing lipid Nalpha-(D)-[3-(hexadecanoyloxy)hexadecanoyl]-ornithine is a strong stimulant for macrophages and a useful adjuvant PubMed ID:10030549
JOURNAL:FEMS Immunol Med Microbiol.
VOL:23 PAGE : 67-73 (1999)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.