Back to HOME

Bile acid


DATA No : BBA0316 INFORMANT : Mizuho Une

NAME : 5b-Cholestane-3a,7a,12a,26-tetrol

COMMON NAME: 27-Deoxy-5b-cyprinol
SYMBOL:
FORMULA: C27H48O4 MOL.WT (average) : 436.668


Download ChemDraw structure data
BIOLOGICAL ACTIVITY

PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:200-201(Ref. 0328/0329)

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:[a]d-23=+36.1pm1(25R), +25pm2(25S)(Ref. 0329)

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:

NMR SPECTRA:

MASS SPECTRA:as DMES derivative (Ref. 0331/0332>

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE
Bile from Rana tigrina ruglosa(Ref. 0330)Urine from patients with cholestasis(Ref. 0331/0332)Human bile(Ref. 0326)Xenopus mulleri(Ref. 0309)Bile from Bufo B. formosus, Bufo B. vulgaris, Bufo maculatus, Bufo marinus, Bufo regularis Arthroleptis, Cardioglossa luecomystax, Dicroglossus occipitalis, Ptychadena aequiplicata, Ptychadena longirostris, Ptychadena maccarthyensis, Ptychadena mascareniensis, Ptychadena oxyrhynchus, Rana ridibunda, Hyperolius concolor ibadensis, Hyperolius fusciventris vurtoni, Hyperolius guttulatus, Hyperolius nitidulus(Ref. 0309)
CHEMICAL SYNTHESIS
(Ref. 0328/0329/0454/0467)
METABOLISM

GENETIC INFORMATION

NOTE

REFERENCES
[0309]
AUTHOR:Anderson,I.G.,Haslewood,G.A.D,Oldham,R.S.,Amos,B.,and Tokes,L.
TITLE:A more detailed study of bile salt evolution, including techniques for small-scale identification and their application to amphibian biles. PubMed ID:4218097
JOURNAL:Biochem.J.
VOL:141 PAGE : 485 -494 (1974)
[TOP]

[0326]
AUTHOR:Kuroki,S.,Shimazu,K.,Kuwabara,M.,Une,M.,Kihira.K.,Kuramoto,T.,and Hoshita,T.
TITLE:Identification of bile alcohols in human bile. PubMed ID:3989382
JOURNAL:J.Lipid Res.
VOL:26 PAGE : 230 -240 (1985)
[TOP]

[0328]
AUTHOR:Kazuno,T.,Masui,T.,and Hoshita,T.
TITLE:Isolation of a new bile sterol, 3a,7a,12a,26-tetrahydroxy-D23-bishomo-cholene from bullfrog bile.
JOURNAL:J. Biochem.
VOL:50 PAGE : 12 -19 (1962)
[TOP]

[0329]
AUTHOR:Anderson, I. G., and Haslewood, G. A.
TITLE:Comparative studies of bile salts. 5 alpha-Chimaerol, a new bile alcohol from the white sucker Catostomus commersoni Lacepede PubMed ID:5435487
JOURNAL:Biochem J.
VOL:116 PAGE : 581-585 (1970)
[TOP]

[0330]
AUTHOR:Une,M.,Matsumoto,N.,Kihira,K.,Yasuhara,M.,Kuramoto,T.,and Hoshita,T.
TITLE:Bile salts of frogs: a new higher bile acid, 3a,7a,12a,26-tetrahydroxy-5b-cholestanoic acid from the bile of Rana plancyi. PubMed ID:7381321
JOURNAL:J.Lipid Res.
VOL:21 PAGE : 269 -276 (1980)
[TOP]

[0331]
AUTHOR:Ichimiya,H.,Yanagisawa,J.,and Nakayama,F.
TITLE:Significance of bile alcohol in urine of a patient with cholestasis: Identification of 5b-cholestane-3a,7a,12a,26,27-pentol (5b-cyprinol) and 5b-cholestane-3a,7a,12a,26-tetrol (27-deoxy-5b-cyprinol). PubMed ID:6499098
JOURNAL:Chem.Pharm.Bull.
VOL:32 PAGE : 2874 -2877 (1984)
[TOP]

[0332]
AUTHOR:Ichimiya,H.,Yanagisawa,J.,and Nakayama,F.
TITLE:Altered metabolism of bile alcohol and bile acid in complete extrahepatic cholestasis: qualitative and quantitative aspects. PubMed ID:3655557
JOURNAL:J.Lipid Res.
VOL:28 PAGE : 1028 -1037 (1987)
[TOP]

[0454]
AUTHOR:Dayal, B., Tint, G. S., Batta, A. K., Shefer, S., and Salen, G.
TITLE:Synthesis of biological precursors of cholic acid II PubMed ID:7222148
JOURNAL:Steroids.
VOL:37 PAGE : 205-211 (1981)
[TOP]

[0467]
AUTHOR:Gengenbacher, T., Gerok, W., Giese, U., and Kurz, G.
TITLE:Synthesis and applicability of photolabile 7,7-azo analogues of natural bile salt precursors PubMed ID:2324650
JOURNAL:J Lipid Res.
VOL:31 PAGE : 315-327 (1990)
[TOP]

Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.