|
| COMMON NAME | : | |
| SYMBOL | : | |
| FORMULA | : | C27H46O4 MOL.WT (average) : 434.652 |
| BIOLOGICAL ACTIVITY |
| PHYSICAL AND CHEMICAL PROPERTIES |
| MELTING POINT | : | 25D:175-176, 25L: non-crystakkine form (Ref. 0412) |
| BOILING POINT | : | |
| REFRACTIVE INDEX | : | |
| OPTICAL ROTATION | : | 25D:[a]D=+5, 25L:[a]D=+18, (Ref. 0412) |
| DENSITY | : | |
| SOLUBILITY | : | |
| SPECTRAL DATA |
| UV SPECTRA | : | |
| IR SPECTRA | : | cm-1 (KBr) 3400,1700 (Ref. 0405) |
| NMR SPECTRA | : | |
| MASS SPECTRA | : | m/z 448,430,412,397,273,264,255,245,228,213,201 (Ref. 0416) |
| OTHER SPECTRA | : | |
| CHROMATOGRAM DATA |
| SOURCE |
| CHEMICAL SYNTHESIS |
| METABOLISM |
| GENETIC INFORMATION |
| NOTE |
| REFERENCES |
| AUTHOR | : | Tint,G.S.,Dayal,B.,Batta,A.K.,Sheffer S.,Joanen,T.,McNease,L.,and Salen,G. |
| TITLE | : | Biliary bile acids, bile alcohols, and sterols of alligator mississippiensis. PubMed ID:7354247 |
| JOURNAL | : | J. Lipid Res. |
| VOL | : | 21 PAGE : 110 -117 (1980) |
| AUTHOR | : | Kihira, K., Okamoto, A., and Hoshita, T. |
| TITLE | : | Identification of new C27 and C24 bile acids in the bile of Alligator mississippiensis PubMed ID:3667554 |
| JOURNAL | : | J Biochem (Tokyo). |
| VOL | : | 101 PAGE : 1377-1384 (1987) |
| AUTHOR | : | Tint, G. S., Dayal, B., Batta, A. K., Shefer, S., Joanen, T., McNease, L., and Salen, G. |
| TITLE | : | The fecal bile acids and sterols of Alligator mississippiensis PubMed ID:7239111 |
| JOURNAL | : | Gastroenterology. |
| VOL | : | 81 PAGE : 114-119 (1981) |
| AUTHOR | : | Parmentier, G. G., Janssen, G. A., Eggermont, E. A., and Eyssen, H. J. |
| TITLE | : | C27 bile acids in infants with coprostanic acidemia and occurrence of a 3 alpha,7 alpha,12 alpha-tridhydroxy-5 beta-C29 dicarboxylic bile acid as a major component in their serum PubMed ID:520320 |
| JOURNAL | : | Eur J Biochem. |
| VOL | : | 102 PAGE : 173-183 (1979) |
| AUTHOR | : | Hoshita, N., and Okuda, K. |
| TITLE | : | Partial synthesis of stero-bile acids related to chenodeoxycholic acid PubMed ID:5589531 |
| JOURNAL | : | J Biochem (Tokyo). |
| VOL | : | 62 PAGE : 655-657 (1967) |
| AUTHOR | : | Briggs, T. |
| TITLE | : | Partial synthesis of 25D- and 25L-cholestanoic acids from some common bile acids PubMed ID:5440333 |
| JOURNAL | : | J Org Chem. |
| VOL | : | 35 PAGE : 1431-1434 (1970) |
| AUTHOR | : | Dean, P. D., and Aplin, R. T. |
| TITLE | : | Mass spectrometric studies on bile acids: the differentiation between chenodeoxycholic acid and deoxycholic acid and the identification of 3alpha, 7alpha-dihydroxy-5beta-cholestanoic acid in alligator bile PubMed ID:6008427 |
| JOURNAL | : | Steroids. |
| VOL | : | 8 PAGE : 565-579 (1966) |
| AUTHOR | : | Hanson,R.F.,Szczepanik-Van Leeuween,P.,Williams,G.C.,Grabowski,G., and Sharp,H.L. |
| TITLE | : | Defects of bile acid synthesis in Zellweger's syndrome. PubMed ID:424737 |
| JOURNAL | : | Science |
| VOL | : | 203 PAGE : 1107 -1108 (1979) |
| AUTHOR | : | Monnens, L., Bakkeren, J., Parmentier, G., Janssen, G., van Haelst, U., Trijbels, F., and Eyssen, H. |
| TITLE | : | Disturbances in bile acid metabolism of infants with the Zellweger (cerebro-hepato-renal) syndrome PubMed ID:7353569 |
| JOURNAL | : | Eur J Pediatr. |
| VOL | : | 133 PAGE : 31-35 (1980) |
| AUTHOR | : | Mathis, R. K., Watkins, J. B., Szczepanik-Van Leeuwen, P., and Lott, I. T. |
| TITLE | : | Liver in the cerebro-hepato-renal syndrome: defective bile acid synthesis and abnormal mitochondria PubMed ID:7439636 |
| JOURNAL | : | Gastroenterology. |
| VOL | : | 79 PAGE : 1311-1317 (1980) |
| AUTHOR | : | Kase, B. F., Bjorkhem, I., Haga, P., and Pedersen, J. I. |
| TITLE | : | Defective peroxisomal cleavage of the C27-steroid side chain in the cerebro-hepato-renal syndrome of Zellweger PubMed ID:3973012 |
| JOURNAL | : | J Clin Invest. |
| VOL | : | 75 PAGE : 427-435 (1985) |
| AUTHOR | : | Kase, B. F., Pedersen, J. I., Strandvik, B., and Bjorkhem, I. |
| TITLE | : | In vivo and vitro studies on formation of bile acids in patients with Zellweger syndrome. Evidence that peroxisomes are of importance in the normal biosynthesis of both cholic and chenodeoxycholic acid PubMed ID:4077985 |
| JOURNAL | : | J Clin Invest. |
| VOL | : | 76 PAGE : 2393-2402 (1985) |
| AUTHOR | : | Deleze, G., Bjorkhem, I., and Karlaganis, G. |
| TITLE | : | Bile acids and bile alcohols in two patients with Zellweger (cerebro-hepato-renal) syndrome PubMed ID:3761102 |
| JOURNAL | : | J Pediatr Gastroenterol Nutr. |
| VOL | : | 5 PAGE : 701-710 (1986) |
| AUTHOR | : | Clayton, P. T., Lake, B. D., Hall, N. A., Shortland, D. B., Carruthers, R. A., and Lawson, A. M. |
| TITLE | : | Plasma bile acids in patients with peroxisomal dysfunction syndromes: analysis by capillary gas chromatography-mass spectrometry PubMed ID:2436918 |
| JOURNAL | : | Eur J Pediatr. |
| VOL | : | 146 PAGE : 166-173 (1987) |
| AUTHOR | : | Kuramoto, T., and Hoshita, T. |
| TITLE | : | The identification of C 27 -bile acids in kite bile PubMed ID:5069745 |
| JOURNAL | : | J Biochem (Tokyo). |
| VOL | : | 72 PAGE : 199-201 (1972) |
| AUTHOR | : | Hanson, R. F., and Williams, G. |
| TITLE | : | The isolation and identification of 3 alpha, 7 alpha-dihydroxy-5 beta-cholestan-26-oic acid from human bile PubMed ID:5113496 |
| JOURNAL | : | Biochem J. |
| VOL | : | 121 PAGE : 863-864 (1971) |
| AUTHOR | : | Kihira, K., Batta, A. K., Mosbach, E. H., and Salen, G. |
| TITLE | : | Reverse cross-coupling in the synthesis 3 alpha, 7 alpha-dihydroxy-5 beta-cholestanoic acid PubMed ID:458264 |
| JOURNAL | : | J Lipid Res. |
| VOL | : | 20 PAGE : 421-427 (1979) |