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Lipopolysaccharide


DATA No : CLS0212 INFORMANT : Yoshio Kumazawa

NAME : 2'N-3""(hexadecanoyloxy)tetradecanoyl,3'N-3""(hexadecanoyloxy)tetradecanoyl, 2',3'-dideoxy b-(1a_right6) D-glucosyl 2N-3""hydroxytetradecanoyl,3-O-3""hydroxytetradecanoyl D-glucosamine 1,4'-bisphosphate

COMMON NAME:
SYMBOL:
FORMULA: C100H189O24N3P2 MOL.WT (average) : 1879.524


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BIOLOGICAL ACTIVITY
Induce toxic lethality in galactosamine-sensitized mice
[Table 0002]
Pyrogenicity in rabbits
Tumor necrosis factor (TNF) secretion from mouse peritoneal macrophages
[Table 0003]
Inhibition of passive haemolysis
[Table 0004]
PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:

NMR SPECTRA:

MASS SPECTRA:Laser desorption mass spectra of dephoshorylated free lipid A
[Spectrum 0009]
EI/MS of permethylated and N-acetylated disaccharides derivatives
[Spectrum 0010]

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE
Campylobactor jejuni(Ref. 0212/0213)
CHEMICAL SYNTHESIS

METABOLISM

GENETIC INFORMATION

NOTE
Chemical composition of LPS of C. jejuni strains
[Table 0005]
Stractural analysis of the lipid A component of Campylobactor jejuni CCUG 10936 (serotype O:2)(Ref. 0213)
REFERENCES
[0212]
AUTHOR: Moran AP
TITLE:Biological and serological characterization of Campylobacter jejuni lipopolysaccharides with deviating core and lipid A structures. PubMed ID:7640672
JOURNAL:FEMS Immunol Med Microbiol
VOL:11 PAGE : 121 -130 (1995)
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[0213]
AUTHOR: Moran A.P, Zahringer U, Seydel U, Scholz D, Stut P, Rietschel ET
TITLE:Structural analysis of the lipid A component of Campylobacter jejuni CCUG 10936 (serotype O:2) lipopolysaccharide. Description of a lipid A containing a hybrid backbone of 2-amino-2-deoxy-D-glucose and 2,3- diamino-2,3-dideoxy-D-glucose. PubMed ID:2040305
JOURNAL:Eur J Biochem
VOL:198 PAGE : 459 -469 (1991)
[TOP]

Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.