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Lipopolysaccharide


DATA No : CLS0421 INFORMANT : Yoshio Kumazawa

NAME : 2N-3''hydroxytetradecanoyl, 3-O-3''hydroxytetradecanoyl D-glucosamine 1-phosphate

COMMON NAME:
SYMBOL:
FORMULA: C34H66O12NP MOL.WT (average) : 711.861


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BIOLOGICAL ACTIVITY
No stimulation of lymphocytes from C3H/HeJ mice
Polymyxin B abrogates lymphocyte stimulation
Induction the proliferation and maturation of lymphocytes to antibody-producing plaque-forming cells(Ref. 0421)
PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:

NMR SPECTRA:

MASS SPECTRA:

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE
Escherichia coli(Ref. 0421)
CHEMICAL SYNTHESIS

METABOLISM

GENETIC INFORMATION

NOTE
Postulated structure of lipid A based on the discovery of lipid X
[Table 0013]
REFERENCES
[0421]
AUTHOR:Raetz, C. R., Purcell, S., and Takayama, K.
TITLE:Molecular requirements for B-lymphocyte activation by Escherichia coli lipopolysaccharide PubMed ID:6348772
JOURNAL:Proc Natl Acad Sci U S A.
VOL:80 PAGE : 4624-4628 (1983)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.