Lipopolysaccharide

DATA No : CLS0421 INFORMANT : Yoshio Kumazawa

NAME : 2N-3''hydroxytetradecanoyl, 3-O-3''hydroxytetradecanoyl D-glucosamine 1-phosphate

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SYMBOL	:
FORMULA	:	C₃₄H₆₆O₁₂NP MOL.WT (average) : 711.861

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BIOLOGICAL ACTIVITY

No stimulation of lymphocytes from C3H/HeJ mice
Polymyxin B abrogates lymphocyte stimulation
Induction the proliferation and maturation of lymphocytes to antibody-producing plaque-forming cells(Ref. 0421)

PHYSICAL AND CHEMICAL PROPERTIES

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CHROMATOGRAM DATA

SOURCE

Escherichia coli(Ref. 0421)

CHEMICAL SYNTHESIS

METABOLISM

GENETIC INFORMATION

NOTE

Postulated structure of lipid A based on the discovery of lipid X
[Table 0013]

REFERENCES

[0421]

AUTHOR	:	Raetz, C. R., Purcell, S., and Takayama, K.
TITLE	:	Molecular requirements for B-lymphocyte activation by Escherichia coli lipopolysaccharide PubMed ID:6348772
JOURNAL	:	Proc Natl Acad Sci U S A.
VOL	:	80 PAGE : 4624-4628 (1983)

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