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Lipopolysaccharide


DATA No : CLS0712 INFORMANT : Yoshio Kumazawa

NAME : 2'N-3''(octadecanoyloxy)octadecanoyl b-(1a_right6) D-glucosaminyl 2N-3''hydroxyoctadecanoyl,3-O-3''hydroxyhexadecanoyl D-glucosamine 1-phosphate

COMMON NAME:
SYMBOL:
FORMULA: C82H156O19N2P MOL.WT (average) : 1505.092


Download ChemDraw structure data
BIOLOGICAL ACTIVITY
Avoid or minimize the host defence(Ref. 0713)
Low pyrogenicity and toxicity
PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:

NMR SPECTRA:31P-NMR spectrum of free lipid A
[Spectrum 0083]

MASS SPECTRA:EI mass spectrum of the permethylated and N-acetylated disaccharide derived from free lipid A
[Spectrum 0082]
Positive-ion LD mass spectra of free dephosphorylated lipid A
[Spectrum 0084]
Assaignment of peaks in the LD mass spectrum of free dephosphorylated lipid A
[Tables 0026/0027]

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE
Helicobacter pylori(Ref. 0712)
CHEMICAL SYNTHESIS

METABOLISM

GENETIC INFORMATION

NOTE
Chemical composition of lipid A
[Table 0023]
Identity of methylated sugars
[Table 0024]
Nature and amount of fatty acid methyl esters released from free lipid A
[Table 0025]
Fragmentation patterns of permethylated and N-acylated glucosamine derivatives
[Spectrum 0085]
REFERENCES
[0712]
AUTHOR:Moran AP, Lindner B, Walsh EJ
TITLE:Structural characterization of the lipid A component of Helicobacter pylori rough- and smooth-form lipopolysaccharides. PubMed ID:9335296
JOURNAL: J Bacteriol
VOL:179 PAGE : 6453 -6463 (1997)
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[0713]
AUTHOR:Lee,A., and Moran,A.P. (1994) Lipopolysaccharide (LPS)-related damage by H. pylori, in Helicobacter pylori: basic mechanisms to clinical cure (Hunt,R.H. and Tytgat,G.N.J., eds), pp146-161, Kluwer Academic Publishers, Dordrecht, The Netherlands
TITLE:
JOURNAL:
VOL: PAGE : - ()
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.