Lipopolysaccharide

DATA No : CLS1311 INFORMANT : Yoshio Kumazawa

NAME : 2'N-3''(dodecanoyloxy)tetradecanoyl, 3'-O-3''hydroxydodecanoyl b-(1

6) D-glucosaminyl 2N-3''(dodecanoyloxy)tetradecanoyl, 3-O-3''hydroxydodecanoyl D-glucosamine 4'-phosphate

COMMON NAME	:
SYMBOL	:
FORMULA	:	C₈₈H₁₆₄O₂₂N₂P MOL.WT (average) : 1633.218

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BIOLOGICAL ACTIVITY

PHYSICAL AND CHEMICAL PROPERTIES

MELTING POINT	:

BOILING POINT	:

REFRACTIVE INDEX	:

OPTICAL ROTATION	:

DENSITY	:

SOLUBILITY	:

SPECTRAL DATA

UV SPECTRA	:

IR SPECTRA	:

NMR SPECTRA	:

MASS SPECTRA	:	HPLC of MLA fraction I, and LD-mass spectra [Spectrum 0033] FAB-mass spectrum of HPLC peak 1-3 from MLA fraction I [Spectrum 0034]

OTHER SPECTRA	:

CHROMATOGRAM DATA

Analytical TLC of silicic acid column purified MLA fractions
[Chromatogram 0011]

SOURCE

Neisseria gonorrhoeae(Ref. 1311)

CHEMICAL SYNTHESIS

METABOLISM

GENETIC INFORMATION

NOTE

Fatty acid distribution of HPLC-fractionated dimethyl MLA, fraction I
[Table 0032]
Fatty acid distribution of the major MLA components obtained from the LPS
[Table 0034]

REFERENCES

[1311]

AUTHOR	:	Takayama K, Qureshi N, Hyver K, Honovich J, Cotter RJ, Mascagni P, Schneider H
TITLE	:	Characterization of a structural series of lipid A obtained from the lipopolysaccharides of Neisseria gonorrhoeae. Combined laser desorption and fast atom bombardment mass spectral analysis of high performance liquid chromatography-purified dimethyl derivatives. PubMed ID:3090037
JOURNAL	:	J Biol Chem
VOL	:	261 PAGE : 10624 -10631 (1986)

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