Back to HOME

Fatty acid


DATA No : DFA8134 INFORMANT : Tetsuyuki Kobayashi

NAME : 11R-hydroxy-5Z,8Z,12E,14Z-eicosatetraenoic acid

COMMON NAME:
SYMBOL: 11(R)-HETE
FORMULA: C20H32O3 MOL.WT (average) : 320.466


Download ChemDraw structure data
Download Mol format file
BIOLOGICAL ACTIVITY
11(R)-HETE has been associated with sea urchin fertilization and/or maturation, as well as hydroid tentacle regeneration (Ref. 8161/8162).
PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:lmax: 235nm e: 27,000

IR SPECTRA:

NMR SPECTRA:

MASS SPECTRA:

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE
11(R)-HETE is synthesized from arachidonic acid by novel 11(R)-lipoxygenases present in the sea urchin eggs, S.purpuratus, and the freshwater hydrozoan, H. vulgaris (Ref. 8161/8162).
CHEMICAL SYNTHESIS

METABOLISM

GENETIC INFORMATION

NOTE

REFERENCES
[8161]
AUTHOR:Hawkins, D.J. and Brash, A.R.
TITLE:Eggs of the sea urchin, Strongylocentrotus Purpuratus, contain a prominent (11R) and (12R) lipoxygenase activity. PubMed ID:3108255
JOURNAL:J. Biol. Chem.
VOL:262 PAGE : 7629 -7634 (1987)
[TOP]

[8162]
AUTHOR:Di Marzo, V., Gianfrani, C., De Petrocellis, L., Milone, A., and Cimino, G.
TITLE:Polyunsaturated-fatty-acid oxidation in Hydra: regioselectivity, substrate-dependent enantioselectivity and possible biological role PubMed ID:8002956
JOURNAL:Biochem J.
VOL:300 (Pt 2) PAGE : 501-507 (1994)
[TOP]

Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.