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Long chain base and Ceramide


DATA No : DLB0012 INFORMANT : Akira Hayashi

NAME : Eicosasphinganine/ 1,3-Dihydroxy-2-aminoeicosane (Ref. 0016/0026/0028)

COMMON NAME:
SYMBOL: d20:0
FORMULA: C20H43O2N1 MOL.WT (average) : 329.561


Download ChemDraw structure data
BIOLOGICAL ACTIVITY

PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:IR of DNP-derivative shows the same spectrum as that of DNP-C18-dihydrosphingosine.

NMR SPECTRA:

MASS SPECTRA:

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE
Milk sphingomyelin (0.6mole%) (Ref. 0016)/Mild alkali stable lipids obtained from yeast, Hansenula (0.4%)(Ref. 0021)/Human brain gangliosides(Ref. 0026)/Ox brain gangliosides (Ref. 0026)/Hair gangliosides (Ref. 0026) / Human brain gray-white matter gangliosides(1-2%) (Ref. 0027) / 18% in long chain bases of mucolipids obtained from ox brain (Ref. 0028).
CHEMICAL SYNTHESIS

METABOLISM

GENETIC INFORMATION

NOTE
Element analyisis of DNP-derivative (Ref. 0026).
REFERENCES
[0016]
AUTHOR:Morrison, W. R.
TITLE:Polar lipids in bovine milk. I. Long-chain bases in sphingomyelin PubMed ID:5816447
JOURNAL:Biochim Biophys Acta.
VOL:176 PAGE : 537-546 (1969)
[TOP]

[0021]
AUTHOR:Karlsson, K.-A.
TITLE:Studies on sphingosines. II. The chemical structure of phytosphingosine of human origin and a note on the lipid composition of the yeast Hansenula ciferrii. PubMed ID:5964492
JOURNAL:Acta Chem. Scand.
VOL:20 PAGE : 2884 -2885 (1966)
[TOP]

[0026]
AUTHOR:Karlsson, K.-A.
TITLE:Studies on sphingosines. III. C20-dihydrosphingosine, a hitherto unknown sphingosine.
JOURNAL:Acta Chem. Scand.
VOL:18 PAGE : 565 -566 (1964)
[TOP]

[0027]
AUTHOR:Sambasivarao, K. and McCluer, R.H.
TITLE:Lipid components of gangliosides.
JOURNAL:J. Lipid Res.
VOL:5 PAGE : 103 -108 (1964)
[TOP]

[0028]
AUTHOR:Stanacev, N.Z. and Chargaff, E.
TITLE:Studies on the chemistry of mucolipids: Occurrence of the long-chain base icosasphingosine, composition of fatty acids, fractionation attempts.
JOURNAL:Biochim. Biophys. Acta
VOL:98 PAGE : 168 -181 (1965)
[TOP]

Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.