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Long chain alcohol


DATA No : DLL0014 INFORMANT : Yasushi Kawakami

NAME : 14-O-acetyl-8,9(E)-10,11(E)-diepoxy-12(E)-en-2,4,6-triyn-tetradecan-1-ol

COMMON NAME: gummiferol
SYMBOL:
FORMULA: C16H14O5 MOL.WT (average) : 286.279


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BIOLOGICAL ACTIVITY
This compound exhibits significant cytotoxic activity against the KB human cell line and broad cytotoxic spectrum against other human cancer cell lines
PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:[a]d-25 -170deg (c=0.2 MeOH) (Ref. 0055)

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:(Ref. 0055)

IR SPECTRA:(Ref. 0055)

NMR SPECTRA:(Ref. 0055)

MASS SPECTRA:(Ref. 0055)

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE
This compound was isolated from the leaves of Adenia gummifera.
CHEMICAL SYNTHESIS

METABOLISM

GENETIC INFORMATION

NOTE

REFERENCES
[0055]
AUTHOR:Fullas, F., Brown, D. M., Wani, M. C., Wall, M. E., Chagwedera, T. E., Farnsworth, N. R., Pezzuto, J. M., and Kinghorn, A. D.
TITLE:Gummiferol, a cytotoxic polyacetylene from the leaves of Adenia gummifera PubMed ID:8676132
JOURNAL:J Nat Prod.
VOL:58 PAGE : 1625-1628 (1995)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.