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Long chain alcohol


DATA No : DLL0019 INFORMANT : Yasushi Kawakami

NAME : 1,9(Z)-heptadecadien-4,6-diyn-3-ol

COMMON NAME: Panaxynol
SYMBOL:
FORMULA: C17H24O MOL.WT (average) : 244.372


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BIOLOGICAL ACTIVITY
This compound shows a growth-inhibitory activity against ML-1 cells,B-16 cells,L-929 cells,MRC-5 cells,Mesothelial cells.(Ref. 0064) This compound inhibits the formation of thromboxane B2 in human platelets.(Ref. 0088)
PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:

BOILING POINT:

REFRACTIVE INDEX:nd-18 1.5018 (Ref. 0085)

OPTICAL ROTATION:

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:(Ref. 0088)

IR SPECTRA:(Ref. 0085)(Ref. 0088)

NMR SPECTRA:(Ref. 0037)(Ref. 0085)(Ref. 0088)(Ref. 0089)

MASS SPECTRA:

OTHER SPECTRA:
CHROMATOGRAM DATA
(Ref. 0084)
SOURCE
This compound was isolated from red ginseng.(Ref. 0064) This compound was isolated from Saposhnikoviae radix(fangfeng,root of Saposhnikovia divaricata Schischk.,Umbelliferae)(Ref. 0088)
CHEMICAL SYNTHESIS
(Ref. 0085)
METABOLISM

GENETIC INFORMATION

NOTE

REFERENCES
[0037]
AUTHOR:Philip,K.,Nicholas,J.,D.,Sjoerd,W.
TITLE:A Stereoselective Synthesis of Tri-substituted Alkenes. The Nickel-Catalyzed Coupling of Grignard reagents with 6-Alkyl-3,4-dihydro-2H-pyrans.
JOURNAL:Tetrahedoron Letters
VOL:29 PAGE : 2353 -2356 (1988)
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[0064]
AUTHOR:Matsunaga, H., Katano, M., Yamamoto, H., Fujito, H., Mori, M., and Takata, K.
TITLE:Cytotoxic activity of polyacetylene compounds in Panax ginseng C. A. Meyer PubMed ID:2092947
JOURNAL:Chem Pharm Bull (Tokyo).
VOL:38 PAGE : 3480-3482 (1990)
[TOP]

[0084]
AUTHOR:Kitagawa, I., Yoshikawa, M., Yoshihara, M., Hayashi, T., and Taniyama, T.
TITLE:[Chemical studies of crude drugs (1). Constituents of Ginseng radix rubra] PubMed ID:6655550
JOURNAL:Yakugaku Zasshi.
VOL:103 PAGE : 612-622 (1983)
[TOP]

[0085]
AUTHOR:H.,J.,Bestmann,W.,Stransky,O.,Vostrowsky,P.,Range
TITLE:Synthese von 1-substituierten (Z)-9-Alkenen
JOURNAL:Chem.Ber.
VOL:108 PAGE : 3582 -3595 (1975)
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[0088]
AUTHOR:Baba,K.,Tamata,Y.,Kozawa,M.,Kimura,Y.,Arichi,S.
TITLE:Studies on Chinese Traditional Medicine Fang-Feng"" (I) Structures and Physiological Activities of Polyacetylene Compounds from Saposhnikoviae Radix""
JOURNAL:Syoyakugaku Zasshi
VOL:41 PAGE : 189 -194 (1987)
[TOP]

[0089]
AUTHOR:Smith, R. G., Daterman, G. E., Daves, G. D., Jr., McMurtrey, K. D., and Roelofs, W. L.
TITLE:Sex pheromone of the European pine shoot moth: chemical identification and field tests PubMed ID:4833352
JOURNAL:J Insect Physiol.
VOL:20 PAGE : 661-668 (1974)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.