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Glycoglycerolipid and others


DATA No : GGG0003 INFORMANT : Ineo Ishizuka

NAME : 1,2-Di-O-acyl-3-[b-galactopyranosyl]-sn-glycerol

COMMON NAME: Monogalactosyldiglyceride, galactosyldiacylglycerol
SYMBOL: GalDAG
FORMULA: MOL.WT (average) :


Download ChemDraw structure data
BIOLOGICAL ACTIVITY
(Ref. 0209).
PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:(Ref. 0229)

NMR SPECTRA:1H-NMR in light water (Ref. 0229).

MASS SPECTRA:FAB-MS: molecular species (Ref. 0113).

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE
The acidophilic alga Dunaliella acidophila, 1.4% of the dry weight (Ref. 0113); Cyanobacterium Phormidium tenue(Ref. 0227); plant (Ref. 0209); Bull frog and axolotl (Ref. 0237); porcine testis (Ref. 0058); cod brain (Ref. 0021/0074); human brain (Ref. 0009); the brain of rat treated chronically with diazepam (Ref. 0055); frog brain (Ref. 0029); rat brain (Ref. 0060), regional distribution in rat brain (Ref. 0020)the primary culture of fetal rat brain (Ref. 0037); subcellular distribution in sheep brain (Ref. 0020); chemical synthesis (Ref. 0229).
CHEMICAL SYNTHESIS
(Ref. 0210/0229)
METABOLISM

GENETIC INFORMATION
Cloning of the gene for UDPgalactose:1,2-diacylglycerol 3-beta-D-galactosyltransferase (Ref. 0246)
NOTE
Treatment with lipase (Ref. 0227).
The acidophilic alga Dunaliella acidophila, the major molecular species 18:3/16:4 (Ref. 0113); cod brain, more than 90% was diacyl species (Ref. 0021/0074), rat brain, fatty acid composition:16:0, 43.8%;18:1, 23.4%; 18:0, 20.9% (Ref. 0060).
REFERENCES
[0009]
AUTHOR:Neskovic,N.,Sarlieve,L.,Nussbaum,J.-L.,Kostic,D., and Mandel,P.
TITLE:Quantitative thin-layer chromatography of glycolipids in animal tissues. PubMed ID:5031779
JOURNAL:Clin. Chim. Acta
VOL:38 PAGE : 147 -153 (1972)
[TOP]

[0020]
AUTHOR:Nonaka,G., and Kishimoto,Y.
TITLE:Levels of cerebrosides, sulfatides, and galactosyl diglycerides in different regions of rat brain - change during maturation and distributionin subcellular fractions of gray and white matter of sheep brain. PubMed ID:435504
JOURNAL:Biochim. Biophys. Acta
VOL:572 PAGE : 432 -441 (1979)
[TOP]

[0021]
AUTHOR:
TITLE:Tamai,Y.,Kojima,H.,Abe,K.,And Saito,S. (1982) Glycolipid composition of fish brains and its bearing on the phylogeny in New Vistas in Glycolipid Research (Makita,A., Handa,S.,Taketomi, T., and Nagai,Y.,eds.), pp315-323.
JOURNAL:
VOL: PAGE : - ()
[TOP]

[0029]
AUTHOR:Saito,S., and Tamai,Y.
TITLE:Characteristic constituents of glycolipids from frog and sciatic nerve. PubMed ID:6603493
JOURNAL:J. Neurochem.
VOL:41 PAGE : 737 -744 (1983)
[TOP]

[0037]
AUTHOR:Singh, H., and Pfeiffer, S. E.
TITLE:Myelin-associated galactolipids in primary cultures from dissociated fetal rat brain: biosynthesis, accumulation, and cell surface expression PubMed ID:4045454
JOURNAL:J Neurochem.
VOL:45 PAGE : 1371-1381 (1985)
[TOP]

[0055]
AUTHOR:Vrbaski,S.R.,Ristic,V.I.,Petrovic,G.T., and Ristic,M.S.
TITLE:Brain lipids in rat after chronic diazepam treatment. PubMed ID:2753868
JOURNAL:J. Biochem.
VOL:105 PAGE : 705 -707 (1989)
[TOP]

[0058]
AUTHOR:Ishizuka, I., Suzuki, M., and Yamakawa, T.
TITLE:Isolation and characterization of a novel sulfoglycolipid, 'seminolipid,' from boar testis and spermatozoa PubMed ID:4690236
JOURNAL:J Biochem (Tokyo).
VOL:73 PAGE : 77-87 (1973)
[TOP]

[0060]
AUTHOR:Levine, M., Kornblatt, M. J., and Murray, R. K.
TITLE:Isolation and partial characterization of a sulfogalactoglycerolipid from rat brain PubMed ID:1139406
JOURNAL:Can J Biochem.
VOL:53 PAGE : 679-689 (1975)
[TOP]

[0074]
AUTHOR:Tamai, Y.
TITLE:[Evolution of glycolipids in the vertebrate nervous system--phylogenical distribution of myelin glycolipids and its physiological significances] PubMed ID:3908583
JOURNAL:Seikagaku.
VOL:57 PAGE : 1249-1270 (1985)
[TOP]

[0113]
AUTHOR:Greca,M.D.,Monaco,P.,Pinto,G.,Pollio,A., and Previtera,L.
TITLE:Lipid composition of the acidophilic alga dunaliella acidophila. Ii. Molecular species of galactolipids.
JOURNAL:Biochim. Biophys. Acta
VOL:1004 PAGE : 271 -273 (1989)
[TOP]

[0209]
AUTHOR:Ishizuka, I., And Yamakawa, T.
TITLE:Glycoglycerolipids.
JOURNAL:New Comprehensive Biochemistry
VOL:10 PAGE : 101 -197 (1985)
[TOP]

[0210]
AUTHOR:Gigg, J., And Gigg, R.(1990) Synthesis of glycoglycerolipids (Kates, M. ed.), pp489-506, Plenum Press, New York
TITLE:
JOURNAL:
VOL: PAGE : - (1990)
[TOP]

[0227]
AUTHOR:Murakami, N., Morimoto, T., Imamura, H., Nagatsu, A., and Sakakibara, J.
TITLE:Enzymatic transformation of glyceroglycolipids into sn-1 and sn-2 lysoglyceroglycolipids by use of Rhizopus arrhizus lipase.
JOURNAL:JLTetrahedron
VOL:50 PAGE : 1993 -2002 (1994)
[TOP]

[0229]
AUTHOR:Mannock, D. A., Ruthven, N. A. H., Lewis, R.N. A. H,. and McElhaney, R. N.
TITLE:The chemical synthesis and physical characterization of 1,2-di-O-acyl-3-O-(a-D-glucopyranosyl)-sn-glycerols, an important class of membrane glycolipids.
JOURNAL:Chem. Phys. Lipids
VOL:55 PAGE : 309 -321 (1990)
[TOP]

[0237]
AUTHOR:Tamai, Y., Kojima, H., Saito, S., Uchida, K., Kitajima, R; Komatsu, H., and Moriya, T.
TITLE:Metamorphic changes in glycolipids and myelin proteins and 2',3'-cyclic nucleotide 3'-phosphohydrolase in bullfrog and axolotl brains. PubMed ID:8386225
JOURNAL:J. Neurochem.
VOL:60 PAGE : 1854 -1863 (1993)
[TOP]

[0246]
AUTHOR:Shimojima, M., Ohta, H., Iwamatsu, A., Masuda, T., Shioi, Y., and Takamiya, K.
TITLE:Cloning of the gene for monogalactosyldiacylglycerol synthase and its evolutionary origin PubMed ID:8990209
JOURNAL:Proc Natl Acad Sci U S A.
VOL:94 PAGE : 333-337 (1997)
[TOP]

Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.