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Glycosphingolipid


DATA No : GSG0072 INFORMANT : Ineo Ishizuka

NAME : bis-sulfo-Gangliotriaosylceramide

COMMON NAME: bis-sulfo-Gangliotriaosylceramide
SYMBOL: SB2
FORMULA: MOL.WT (average) :


Download ChemDraw structure data
BIOLOGICAL ACTIVITY
Interaction with laminin, thrombospondin, and von willebrand factor (Ref. 0044).
PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:

DENSITY:

SOLUBILITY:Behavior in the Folch partition (Ref. 0027).
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:The sulfate ester, 1240,820cm-1 (Ref. 0079).

NMR SPECTRA:1H-NMR (Ref. 0080).

MASS SPECTRA:EI-MS (trideuteriomethylated after permethylation-soluvolysis) (Ref. 0080); Hex, m/z 219+3; Hex-CD3OH, m/z 187 (Ref. 0080/0033), SI-MS (Ref. 0036). Negative-mode LSIMS and CID (Ref. 0214).

OTHER SPECTRA:Absorption of the complex with Azure A,the abssorption of the acetates of sulfoglycolipids with Azure A (Ref. 0027).
CHROMATOGRAM DATA

SOURCE
Review (Ref. 0208). Rat kidney (Ref. 0079/0080).
CHEMICAL SYNTHESIS

METABOLISM

GENETIC INFORMATION

NOTE

The long-chain base is predominantly t18:0 (Ref. 0208)
REFERENCES
[0027]
AUTHOR:Tadano-Aritomi,K., and Ishizuka,I.
TITLE:Determination of peracetylated sulfoglycolipids using the azure A method. PubMed ID:6196425
JOURNAL:J. Lipid Res.
VOL:24 PAGE : 1368 -1375 (1983)
[TOP]

[0033]
AUTHOR:Ishizuka, I., and Tadano-Aritomi, K.
TITLE:Characterization of sulfoglycosphingolipids by direct probe electron impact mass spectrometry PubMed ID:6501265
JOURNAL:J Biochem (Tokyo).
VOL:96 PAGE : 829-839 (1984)
[TOP]

[0036]
AUTHOR:Kushi, Y., Handa, S., and Ishizuka, I.
TITLE:Secondary ion mass spectrometry for sulfoglycolipids: application of negative ion detection PubMed ID:4008462
JOURNAL:J Biochem (Tokyo).
VOL:97 PAGE : 419-428 (1985)
[TOP]

[0044]
AUTHOR:Roberts, D. D., Rao, C. N., Liotta, L. A., Gralnick, H. R., and Ginsburg, V.
TITLE:Comparison of the specificities of laminin, thrombospondin, and von Willebrand factor for binding to sulfated glycolipids PubMed ID:3486185
JOURNAL:J Biol Chem.
VOL:261 PAGE : 6872-6877 (1986)
[TOP]

[0079]
AUTHOR:Tadano, K., and Ishizuka, I.
TITLE:Isolation and partial characterization of a novel disulfoglycosphingolipid from rat kidney PubMed ID:7332569
JOURNAL:Biochem Biophys Res Commun.
VOL:103 PAGE : 1006-1013 (1981)
[TOP]

[0080]
AUTHOR:Tadano, K., and Ishizuka, I.
TITLE:Bis-sulfoglycosphingolipid containing a unique 3-O-sulfated N-acetylgalactosamine from rat kidney PubMed ID:7107569
JOURNAL:J Biol Chem.
VOL:257 PAGE : 9294-9299 (1982)
[TOP]

[0208]
AUTHOR:Ishizuka, I.
TITLE:Chemistry and functional distribution of sulfoglycolipids PubMed ID:9640458
JOURNAL:Prog Lipid Res.
VOL:36 PAGE : 245-319 (1997)
[TOP]

[0214]
AUTHOR:Tadano-Aritomi, K., Kubo, H., Ireland, P., Okuda, M., Kasama, T., Handa, S., and Ishizuka, I.
TITLE:Structural analysis of mono- and bis-sulfated glycosphingolipids by negative liquid secondary ion mass spectrometry with high- and low-energy collision-induced dissociation PubMed ID:7553669
JOURNAL:Carbohydr Res.
VOL:273 PAGE : 41-52 (1995)
[TOP]

Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.