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Isoprenoid


DATA No : IIP0007 INFORMANT : Hiroshi Sagami

NAME : [2Z,6E,10E]-3,7,11,15-Tetramethyl-2,6,10,14-hexadecatetraen-1-yl diphosphate

COMMON NAME: w-E,E,Z-Geranylgeranyl diphosphate, Cis-Geranylgeranyl diphosphate, geranylneryl diphosphate
SYMBOL:
FORMULA: C20H36O7P2 MOL.WT (average) : 450.443


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BIOLOGICAL ACTIVITY

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CHEMICAL SYNTHESIS
The compound can be synthesized from cis-geranylgeraniol .(Ref. 0014)
METABOLISM
The product formed by the action of cis-geranylgeranyl diphosphate synthase and the first product by the action of dehydrodolichul diphosphate synthase from farnesyl diphosphate and isopentenyl diphosphate.(Ref. 0026)
GENETIC INFORMATION

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REFERENCES
[0014]
AUTHOR:Davisson,V. J., Woodside,A. B., Neal, T. R., Stremler, K. E., Muehlbacher, M., and Poulter, C. D.
TITLE:Phosphorylation of isoprenoid alcohols.
JOURNAL:J. Org. Chem.
VOL:51 PAGE : 4768 -4779 (1986)
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[0026]
AUTHOR:Sagami, H., Matsuoka, S., and Ogura, K.
TITLE:Formation of Z,E,E-geranylgeranyl diphosphate by rat liver microsomes PubMed ID:1995610
JOURNAL:J Biol Chem.
VOL:266 PAGE : 3458-3463 (1991)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.