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Glycerophospholipid


DATA No : PGP3017 INFORMANT : Keizo Waku

NAME : 1-Palmitoyl-2-docosahexanoyl-sn-glycero-3-phosphocholine

COMMON NAME: Palmitoyl-docosahexanoyl lecithin
SYMBOL:
FORMULA: C46H80O8NP MOL.WT (average) : 806.103


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BIOLOGICAL ACTIVITY

PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:

BOILING POINT:

REFRACTIVE INDEX:Force-area characteristics of this lecithin was estimated. (Ref. 3003)

OPTICAL ROTATION:

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:

NMR SPECTRA:

MASS SPECTRA:

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE

CHEMICAL SYNTHESIS
Dipalmitoyl lecithin was synthesized from L-a-glycerophosphocholine, obtained from egg lecithin, and palmitoyl chloride in anhydrous chloroform. Dipalmitoyl lecithin was hydrolyzed by phospholipase A2 and the resultant 1-palmitoyl glycerophosphocholine was acylated with docosahexanoyl chloride. (Ref. 3002)
METABOLISM

GENETIC INFORMATION

NOTE

REFERENCES
[3002]
AUTHOR:L.L.M. Van Deenen and G.H.De Haas
TITLE:The Synthesis of Phosphoglycerides and Some Biochemical Applications.
JOURNAL:Advan. Lipid Res.
VOL:2 PAGE : 167 -234 (1964)
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[3003]
AUTHOR:Demiel, R. A., Guerts van Kessel, W. S., and van Deenen, L. L.
TITLE:The properties of polyunsaturated lecithins in monolayers and liposomes and the interactions of these lecithins with cholesterol PubMed ID:5064891
JOURNAL:Biochim Biophys Acta.
VOL:266 PAGE : 26-40 (1972)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.