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Sphingophospholipid


DATA No : PSP5012 INFORMANT : Kentaro Hanada

NAME : dihydroceramide-1-phosphorylcholine

COMMON NAME: Dihydrosphingomyelin
SYMBOL: DSM
FORMULA: MOL.WT (average) :


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BIOLOGICAL ACTIVITY

PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:

DENSITY:

SOLUBILITY:insoluble in water; solble in chloroform
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:

NMR SPECTRA:

MASS SPECTRA:

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE
Ubiquitous in mammalian (probably ubiquitous in vertebrates)(Ref. 5001)
CHEMICAL SYNTHESIS

METABOLISM
DSM is formed by phosphorylcholine transfer from phosphatidylcholine to dihydroceramide. In general, the DSM level in cells is lower than the level of sphingomyelin.(Ref. 5002)
GENETIC INFORMATION

NOTE

REFERENCES
[5001]
AUTHOR:Karlsson,K-A.
TITLE:On the Chemistry and Occurrence of Sphingolipid Long-Chain Bases. PubMed ID:4394487
JOURNAL:Chem.Phys.Lipids
VOL:5 PAGE : 6 -43 (1970)
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[5002]
AUTHOR:Merrill,A.H.Jr.,and Sweeley,C.C.(1996)Sphingolipids:metabolism and cell signalling(Vance,D.E.,and Vance,J.E.,eds),pp309-339,Elsevier Science B.V.,Amsterdam
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.