Sphingophospholipid

DATA No : PSP5012 INFORMANT : Kentaro Hanada

NAME : dihydroceramide-1-phosphorylcholine

COMMON NAME	:	Dihydrosphingomyelin
SYMBOL	:	DSM
FORMULA	:	MOL.WT (average) :

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BIOLOGICAL ACTIVITY

PHYSICAL AND CHEMICAL PROPERTIES

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SOLUBILITY	:	insoluble in water; solble in chloroform

SPECTRAL DATA

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CHROMATOGRAM DATA

SOURCE

Ubiquitous in mammalian (probably ubiquitous in vertebrates)(Ref. 5001)

CHEMICAL SYNTHESIS

METABOLISM

DSM is formed by phosphorylcholine transfer from phosphatidylcholine to dihydroceramide. In general, the DSM level in cells is lower than the level of sphingomyelin.(Ref. 5002)

GENETIC INFORMATION

NOTE

REFERENCES

[5001]

AUTHOR	:	Karlsson,K-A.
TITLE	:	On the Chemistry and Occurrence of Sphingolipid Long-Chain Bases. PubMed ID:4394487
JOURNAL	:	Chem.Phys.Lipids
VOL	:	5 PAGE : 6 -43 (1970)

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[5002]

AUTHOR	:	Merrill,A.H.Jr.,and Sweeley,C.C.(1996)Sphingolipids:metabolism and cell signalling(Vance,D.E.,and Vance,J.E.,eds),pp309-339,Elsevier Science B.V.,Amsterdam
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VOL	:	PAGE : - ()

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