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Steroid


DATA No : SST0098 INFORMANT : Hideaki Nishino

NAME : 3a-Hydroxy-5b-pregnan-20-one / Pregnan-3a-ol-20-one

COMMON NAME:
SYMBOL:
FORMULA: C21H34O2 MOL.WT (average) : 318.493


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BIOLOGICAL ACTIVITY
Preparation by hydrolysis of sodium pregnanediol glucuronidate. (Ref. 0478)
PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:149.5degC (hexane). (Ref. 0477/0478)

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:[a]13/D=+109deg (c=0.98 in ethanol). (Ref. 0477/0478)

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:

NMR SPECTRA:

MASS SPECTRA:

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE
In urine of pregnant women, pregnant hogs. (Ref. 0477)
CHEMICAL SYNTHESIS

METABOLISM

GENETIC INFORMATION

NOTE
Not ppt with digitonin. (Ref. 0477)
REFERENCES
[0477]
AUTHOR:Marker,R.E.,and Kamm,O.
TITLE:Sterols. XVII. Isolation of pregnanolone from human pregnancy urine.
JOURNAL:J. Am. Chem. Soc.
VOL:59 PAGE : 1373 -1379 (1937)
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[0478]
AUTHOR:Marrian,G.F.,and Gough,N.
TITLE:The isolation of pregnane-3(a)-ol-20-one from the hydrolysis products of sodium pregnanediol glucuronidate.
JOURNAL:Biochem. J.
VOL:40 PAGE : 376 -380 (1946)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.