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COMMON NAME | : | PROSTAGLANDIN E3 |
SYMBOL | : | PGE3 |
FORMULA | : | C20H30O5 MOL.WT (average) : 350.449 |
BIOLOGICAL ACTIVITY |
PHYSICAL AND CHEMICAL PROPERTIES |
MELTING POINT | : | 84.5-85.5![]() |
BOILING POINT | : | |
REFRACTIVE INDEX | : | |
OPTICAL ROTATION | : | [a]![]() ![]() |
DENSITY | : | |
SOLUBILITY | : | TETRAHYDROFURAN (Ref. 1114) |
SPECTRAL DATA |
UV SPECTRA | : | |
IR SPECTRA | : | |
NMR SPECTRA | : | METHYL ESTER ; 1H-NMR(CDCl3) : d 5.8-5.5(m, 2H,13, 14-CH), 5.5-5.2(m, 4H, 5,6,17,18-CH), 4.4-3.8(m, 2H, 11,15-CH), 0.95(t, 3H, 20-CH) (Ref. 1115) |
MASS SPECTRA | : | METHYL ESTER ; m/e 346(M-18), 328(M-18x2), 315, 297, 277, 259, 188 (Ref. 1116) |
OTHER SPECTRA | : | |
CHROMATOGRAM DATA |
SOURCE |
CHEMICAL SYNTHESIS |
METABOLISM |
GENETIC INFORMATION |
NOTE |
REFERENCES |
AUTHOR | : | Bergstrom, S. |
TITLE | : | Prostaglandins: members of a new hormonal system. These physiologically very potent compounds of ubiquitous occurrence are formed from essential fatty acids PubMed ID:4291104 |
JOURNAL | : | Science. |
VOL | : | 157 PAGE : 382-391 (1967) |
AUTHOR | : | Bergstrom, S., Carlson, L. A., and Weeks, J. R. |
TITLE | : | The prostaglandins: a family of biologically active lipids PubMed ID:4873508 |
JOURNAL | : | Pharmacol Rev. |
VOL | : | 20 PAGE : 1-48 (1968) |
AUTHOR | : | Speroff, L., and Ramwell, P. W. |
TITLE | : | Prostaglandins in reproductive physiology PubMed ID:4914185 |
JOURNAL | : | Am J Obstet Gynecol. |
VOL | : | 107 PAGE : 1111-1130 (1970) |
AUTHOR | : | Okamoto,S., Kobayashi,Y. and Sato,F. |
TITLE | : | A Highly Efficient Synthesis of Natural PGE3 and 5,6-Dihydro PGE3 via Two-component Coupling Process. |
JOURNAL | : | Tetrah. Lett. |
VOL | : | 30 PAGE : 4379 -4382 (1989) |
AUTHOR | : | Corey, E. J., Shirahama, H., Yamamoto, H., Terashima, S., Venkateswarlu, A., and Schaaf, T. K. |
TITLE | : | Stereospecific total synthesis of prostaglandins E3 and F3 alpha PubMed ID:5548346 |
JOURNAL | : | J Am Chem Soc. |
VOL | : | 93 PAGE : 1490-1491 (1971) |
AUTHOR | : | Samuelsson,B. |
TITLE | : | Prostaglandins and Related Factors. 17. The Structure of Prostaglandin E3. |
JOURNAL | : | J. Am. Chem. Soc. |
VOL | : | 85 PAGE : 1878 -1879 (1963) |
AUTHOR | : | Bergströ$m,S., Dressler,F., Ryhage,R., Samuelsson,B. and Sjö$vall |
TITLE | : | The Isolation of Two Further Prostaglandins from Sheep Prostate Glands. Prostaglndin and Related Factors 8. |
JOURNAL | : | Ark. Kemi. |
VOL | : | 19 PAGE : 563 -567 (1962) |