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COMMON NAME | : | THROMBOXANE B2 |
SYMBOL | : | TXB2 |
FORMULA | : | C20H34O6 MOL.WT (average) : 370.480 |
BIOLOGICAL ACTIVITY |
PHYSICAL AND CHEMICAL PROPERTIES |
MELTING POINT | : | 95-96![]() |
BOILING POINT | : | |
REFRACTIVE INDEX | : | |
OPTICAL ROTATION | : | [a]![]() ![]() |
DENSITY | : | |
SOLUBILITY | : | ETHYL ACETATE (Ref. 1035) |
SPECTRAL DATA |
UV SPECTRA | : | |
IR SPECTRA | : | FILM: n 3380, 1705cm-1 (Ref. 1033) |
NMR SPECTRA | : | 1H-NMR(CDCl3) : d 5.86(m, 1H, 14-CH), 5.72(m, 1H, 13-CH), 5.46(m, 2H, 5,6-CH), 5.35 and 5.23(m, 1H, 11-CH), 4.41(m, 1H, 12-CH), 4.22(m, 1H, 15-CH), 4.11(m, 1H, 9-CH), 2.35(t, 2H, 2-CH2), 0.89(m, 3H, 20-CH3) (Ref. 1034) |
MASS SPECTRA | : | m/e 335, 317 (Ref. 1033) |
OTHER SPECTRA | : | |
CHROMATOGRAM DATA |
SOURCE |
CHEMICAL SYNTHESIS |
METABOLISM |
GENETIC INFORMATION |
NOTE |
REFERENCES |
AUTHOR | : | Moncada, S., and Vane, J. R. |
TITLE | : | Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin PubMed ID:116251 |
JOURNAL | : | Pharmacol Rev. |
VOL | : | 30 PAGE : 293-331 (1978) |
AUTHOR | : | Whittle, B. J., and Moncada, S. |
TITLE | : | Pharmacological interactions between prostacyclin and thromboxanes PubMed ID:6313114 |
JOURNAL | : | Br Med Bull. |
VOL | : | 39 PAGE : 232-238 (1983) |
AUTHOR | : | Kindahl,H. |
TITLE | : | Metabolism of thromboxane B2 in the cynomolgus monkey. PubMed ID:404670 |
JOURNAL | : | Prostaglandins |
VOL | : | 13 PAGE : 619 -629 (1997) |
AUTHOR | : | Westlund, P., Granstrom, E., Kumlin, M., and Nordenstrom, A. |
TITLE | : | Identification of 11-dehydro-TXB2 as a suitable parameter for monitoring thromboxane production in the human PubMed ID:3755250 |
JOURNAL | : | Prostaglandins. |
VOL | : | 31 PAGE : 929-960 (1986) |
AUTHOR | : | Westlund, P., Fylling, A. C., Cederlund, E., and Jornvall, H. |
TITLE | : | 11-Hydroxythromboxane B2 dehydrogenase is identical to cytosolic aldehyde dehydrogenase PubMed ID:8200461 |
JOURNAL | : | FEBS Lett. |
VOL | : | 345 PAGE : 99-103 (1994) |
AUTHOR | : | Hanessian,S., and Lavallee,P. |
TITLE | : | A Stereospecific, Total Synthesis of Thromboxane B2. |
JOURNAL | : | Can. J. Chem. |
VOL | : | 55 PAGE : 562 -565 (1977) |
AUTHOR | : | Kotovych,G., and Aarts,G.H.M. |
TITLE | : | A High Field Proton Magnetic Resonance Study of the Solution Conformation of Thromboxane B2. |
JOURNAL | : | Can. J. Chem. |
VOL | : | 58 PAGE : 1111 -1117 (1980) |
AUTHOR | : | Kelly,R.C., Schletter,I., and Stein,S.J. |
TITLE | : | Synthesis of Thromboxane B2. |
JOURNAL | : | Tetrah. Lett. |
VOL | : | PAGE : 3279 -3282 (1976) |