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Eicosanoid


DATA No : XPR3117 INFORMANT : Takehiko Yokomizo

NAME : 5S,12S-dihydroxy-6Z,8E,10E,14Z-eicsatetraenoic acid

COMMON NAME: 12-epi Leukotriene B4
SYMBOL:
FORMULA: C20H32O4 MOL.WT (average) : 336.466


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BIOLOGICAL ACTIVITY
12-epi LTB4 has a week agonistic character at both recombinant human BLT1 and BLT2 approximately 10 _M for complete activation.(Ref. 2128)
PHYSICAL AND CHEMICAL PROPERTIES
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REFERENCES
[2128]
AUTHOR:Yokomizo, T., Kato, K., Hagiya, H., Izumi, T., and Shimizu, T.
TITLE:Hydroxyeicosanoids bind to and activate the low affinity leukotriene B4 receptor, BLT2 PubMed ID:11278893
JOURNAL:J Biol Chem.
VOL:276 PAGE : 12454-12459 (2001)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.