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Eicosanoid


DATA No : XPR3119 INFORMANT : Takehiko Yokomizo

NAME : 5S,12R-dihydroxy-6Z,8E,10E-eicosatriene-14-ynoic acid

COMMON NAME: 14,15-dehydro Leukotriene B4
SYMBOL:
FORMULA: C20H30O4 MOL.WT (average) : 334.450


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BIOLOGICAL ACTIVITY
14,15-dehydro LTB4 is reported as a selective ligand for the BLT1 and act as a selective antagonist of LTB4 in vivo.(Ref. 2131)
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REFERENCES
[2131]
AUTHOR:Wang, S., Gustafson, E., Pang, L., Qiao, X., Behan, J., Maguire, M., Bayne, M., and Laz, T.
TITLE:A novel hepatointestinal leukotriene B4 receptor. Cloning and functional characterization PubMed ID:11006272
JOURNAL:J Biol Chem.
VOL:275 PAGE : 40686-40694 (2000)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.