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Eicosanoid


DATA No : XPR8054 INFORMANT : Yasuji Yamada

NAME : (5E, 13E)-(8R,12S,15S)-15-hydroxy-9-oxoprost-5,10,13-trienoic acid

COMMON NAME: 5-trans-prostaglandin A2(Ref. 8047)
SYMBOL: 5-trans-PGA2
FORMULA: C20H30O4 MOL.WT (average) : 334.450


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BIOLOGICAL ACTIVITY

PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:[a]D +128deg(CHCl3)(Ref. 8047)

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:lmax 217 nm(e9050))(Ref. 8047)

IR SPECTRA:

NMR SPECTRA:

MASS SPECTRA:HREIMS m/z 478.2998 for TMS derivative C26H46O4 Si2, calcd 478.2932.(Ref. 8047)

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE
5-trans-Prostaglandin A2 was isolated from Gorgonian, Plexaura homomalla.(Ref. 8047)
CHEMICAL SYNTHESIS

METABOLISM

GENETIC INFORMATION

NOTE

REFERENCES
[8047]
AUTHOR:Bundy, G. L., Daniels, E. G., Lincoln, F. H., and Pike, J. E.
TITLE:Isolation of a new naturally occurring prostaglandin, 5-trans-PGA 2. Synthesis of 5-trans-PGE 2 and 5-trans-PGF 2a PubMed ID:4401384
JOURNAL:J Am Chem Soc.
VOL:94 PAGE : 2124- (1972)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.