Category:LBS/Biosynthesis/GIPC: Difference between revisions

No edit summary
No edit summary
Line 11: Line 11:
|-
|-
| colspan="4"|  
| colspan="4"|  
| style="background:darkseagreen" | {{Map/ReactionDown|16:0-CoA||CS I<ref>CS can utilize a range of FA-CoAs (C16-24) but not hydroxy-FA-CoAs. See Sperling P, Heinz E. (2003) Biochim Biophys Acta 1632:1?15.</ref>}}
| style="background:darkseagreen" | {{Map/ReactionDown|LCFA-CoA||CS I<ref>CS can utilize a range of FA-CoAs (C16-24) but not hydroxy-FA-CoAs. See Sperling P, Heinz E. (2003) Biochim Biophys Acta 1632:1?15.</ref>}}
| rowspan="4" style="background:darkseagreen; font-weight: 600; text-shadow:black 3px 3px 5px; color: white; font-size: large"| Lumen of endoplasmic reticulum (ER)
| rowspan="4" style="background:darkseagreen; font-weight: 600; text-shadow:black 3px 3px 5px; color: white; font-size: large"| Lumen of endoplasmic reticulum (ER)
| style="background:darkseagreen" | {{Map/ReactionDown|VLCFA-CoA||CS II}}
| style="background:darkseagreen" | {{Map/ReactionDown|VLCFA-CoA||CS II}}
Line 18: Line 18:
|colspan="4" rowspan="7"|  
|colspan="4" rowspan="7"|  
{| class="wikitable"
{| class="wikitable"
|'''Abbreviations'''<br/>SPT: serine palmitoyltransferase<br/>KSR: 3-ketosphinganine reductase<br/>LCB: long-chain base<br/>GCS: glucosylceramide synthase<br/>CS I/II: (dihydro)ceramide synthase I/II<br/>DES: desaturase<br/>FA OHase: Fatty-acid hydroxylase<br/>MT: methyltransferase<br/>VLCFA: very long-chain fatty acid<br/>IPCS: inositol phosphoceramide synthase<br/>PI: phosphatidylinositol<br/>DAG: diacylglycerol
|'''Abbreviations'''<br/>SPT: serine palmitoyltransferase<br/>KSR: 3-ketosphinganine reductase<br/>LCB: long-chain base<br/>GCS: glucosylceramide synthase<br/>CS I/II: (dihydro)ceramide synthase I/II<br/>DES: desaturase<br/>FA OHase: Fatty-acid hydroxylase<br/>MT: methyltransferase<br/>LCFA: long-chain fatty acid<br/>VLCFA: very long-chain fatty acid<br/>IPCS: inositol phosphoceramide synthase<br/>PI: phosphatidylinositol<br/>DAG: diacylglycerol
|}
|}
| style="background:darkseagreen" | '''d18:0-16:0'''
| style="background:darkseagreen" | '''d18:0-LCFA'''
| style="background:darkseagreen" | '''t18:0-VLCFA'''
| style="background:darkseagreen" | '''t18:0-VLCFA'''
|
|
Line 28: Line 28:
| '''Bold font = ceramides'''
| '''Bold font = ceramides'''
|-
|-
| style="background:darkseagreen" | '''d18:1&Delta;8E/Z-h16:0'''
| style="background:darkseagreen" | '''d18:1&Delta;8E/Z-hLCFA'''
| style="background:darkseagreen" | ''' t18:1&Delta;8E/Z-hVLCFA'''
| style="background:darkseagreen" | ''' t18:1&Delta;8E/Z-hVLCFA'''
|
|
Line 37: Line 37:
|
|
|-  
|-  
|colspan="2" rowspan="3" valign="top"| '''Glc-ceramide'''<br/>Glc-d18:2 4E,8E/Z-h16:0<br/>Glc-d18:1 8E/Z-h16:0<br/>Glc-t18:1-hVLCFA
|colspan="2" rowspan="3" valign="top"| '''Glc-ceramide'''<br/>Glc-d18:2 4E,8E/Z-hLCFA<br/>Glc-d18:1 8E/Z-hLCFA<br/>Glc-t18:1-hVLCFA
|rowspan="3" style="background:darkturquoise;border-radius: 20px 0px 0px 20px;font-weight: 600; text-shadow:black 3px 3px 5px; color: white; font-size: large"| Golgi
|rowspan="3" style="background:darkturquoise;border-radius: 20px 0px 0px 20px;font-weight: 600; text-shadow:black 3px 3px 5px; color: white; font-size: large"| Golgi
| style="background:darkturquoise;border-radius: 0px 20px 0px 0px"| '''t18:1&Delta;8E/Z-hVLCFA'''<br/>(in Golgi)
| style="background:darkturquoise;border-radius: 0px 20px 0px 0px"| '''t18:1&Delta;8E/Z-hVLCFA'''<br/>(in Golgi)

Revision as of 06:38, 13 April 2016

palmitoyl (16:0)-CoA
+
serine 		SPT
Arrow00r.png
 3-keto sphinganine KSR
Arrow00r.png
 sphinganine
d18:0 		LCB C-4 OHase
Arrow00r.png 		phytosphinganine
t18:0
Arrow1ld35.png
LCFA-CoA
CS I[1]
Lumen of endoplasmic reticulum (ER)
Arrow1ld35.png
VLCFA-CoA
CS II
Abbreviations
SPT: serine palmitoyltransferase
KSR: 3-ketosphinganine reductase
LCB: long-chain base
GCS: glucosylceramide synthase
CS I/II: (dihydro)ceramide synthase I/II
DES: desaturase
FA OHase: Fatty-acid hydroxylase
MT: methyltransferase
LCFA: long-chain fatty acid
VLCFA: very long-chain fatty acid
IPCS: inositol phosphoceramide synthase
PI: phosphatidylinositol
DAG: diacylglycerol
d18:0-LCFA t18:0-VLCFA
Arrow00d35.png
Δ8 DES
Δ4 DES
FA-αOHase
(C-9 MT in fungi)
Arrow00d35.png
Δ8 DES
FA-αOHase
Bold font = ceramides
d18:1Δ8E/Z-hLCFA t18:1Δ8E/Z-hVLCFA
Arrow00dr35.png +UDP-Glc +UDP-Glc Arrow00dl35.png transport Arrow00dr35.png
Glc-ceramide
Glc-d18:2 4E,8E/Z-hLCFA
Glc-d18:1 8E/Z-hLCFA
Glc-t18:1-hVLCFA 		Golgi t18:1Δ8E/Z-hVLCFA
(in Golgi)
Arrow3ld.png
PI
IPCS[2]
DAG
GIPC (in Golgi)
  1. ↑ CS can utilize a range of FA-CoAs (C16-24) but not hydroxy-FA-CoAs. See Sperling P, Heinz E. (2003) Biochim Biophys Acta 1632:1?15.
  2. ↑ Activity of IPCS is high in Fabaceae. See Bromley PE, Li YO, Murphy SM, Sumner CM, Lynch DV (2003) Archiv Biochem Biophys 417:219?226

This category currently contains no pages or media.

Retrieved from "http://lipidbank.jp/mediawiki/index.php?title=Category:LBS/Biosynthesis/GIPC&oldid=101075"