LBF20406OX01

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Upper classes: LB LBF



5-Oxo- (6E,8Z,11Z,14Z) -eicosatetraenoic acid
LBF20406OX01.png
Structural Information
5-Oxo- (trans-6,cis-8,cis-11,cis-14) -eicosatetraenoic acid
  • 5-Oxo- (6E,8Z,11Z,14Z) -eicosatetraenoic acid
5-OxoETE/5-KETE
Formula C20H30O3
Exact Mass 318.21949482599996
Average Mass 318.4504
SMILES C(CC=CCC=CCC=CC=CC(CCCC(O)=O)=O)CCC
Physicochemical Information
5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils Powell_WS et al..
It stimulates cytosolic calcium levels in neutrophils with an EC of 2 nM Powell_WS et al.. 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the MAPK pathway in stimulated neutrophils OFlaherty_JT et al. OFlaherty_JT et al..
Spectral Information
Mass Spectra
UV Spectra λ max: 279nm ε : 22,100
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20406OX01 See above. OFlaherty_JT et al. 1996
n.a. LBF20406OX01 See above. OFlaherty_JT et al. 1996
n.a. LBF20406OX01 See above. Powell_WS et al. 1992
n.a. LBF20406OX01 See above. Powell_WS et al. 1994