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| No | Structure | COMMON NAME | NAME | DATA No | INFORMANT | SYMBOL | FORMULA | MOL.WT(ave) | Download | BIOOGICAL ACTIVITY | PHYSICAL AND CHEMICAL PROPERTIES | SPECTRAL DATA | CHROMATOGRAM DATA | SOURCE | CHEMICAL SYNTHESIS | METABOLISM | GENETIC INFORMATION | NOTE | REFERENCES | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MELTING POINT | BOILING POINT | DENSITY | REFRACTIVE INDEX | OPTICAL ROTATION | SOLUBILITY | UV SPECTRA | IR SPECTRA | NMR SPECTRA | MASS SPECTRA | OTHER SPECTRA | ||||||||||||||||||
| 1 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-dicyclopropanoyl-C51:0 acid |
MMA0001 | Nagatoshi Fujiwara |
C49-diD(b-unit)+C22:0(a-unit) |
C71H138O3 | 1039.854 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 2 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-dicyclopropanoyl-C52:0 acid |
MMA0002 | Nagatoshi Fujiwara |
C50-diD(b-unit)+C22:0(a-unit) |
C72H140O3 | 1053.880 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0001/0002] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 3 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-dicyclopropanoyl-C53:0 acid |
MMA0003 | Nagatoshi Fujiwara |
C51-diD(b-unit+C22:0(a-unit) |
C73H142O3 | 1067.907 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0001/0003] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 4 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-dicyclopropanoyl-C54:0 acid |
MMA0004 | Nagatoshi Fujiwara |
C52-diD(b-unit)+C22:0(a-unit) |
C74H144O3 | 1081.933 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0001/0002] |
Mycobacterium vaccae(VA-1) (Ref. 0001/0004/0005) Mycobacterium parafortuitum(19686) (Ref. 0001/0004/0005) Mycobacterium diernhoferi(MD-1) (Ref. 0001/0004/0005) Mycobacterium phlei (Ref. 0005) Mycobacterium rhodesiae(RHO-1) (Ref. 0001/0004/0005) Mycobacterium aurum(Ref. 0004/0005) Mycobacterium kansasii (Ref. 0001) [Table 0001] [Table 0002] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 5 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-dicyclopropanoyl-C55:0 acid |
MMA0005 | Nagatoshi Fujiwara |
C53-diD(b-unit)+C22:0(a-unit) |
C75H146O3 | 1095.960 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0001/0003] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 6 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-dicyclopropanoyl-C56:0 acid |
MMA0006 | Nagatoshi Fujiwara |
C54-diD(b-unit)+C22:0(a-unit) |
C76H148O3 | 1109.987 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+) [Spectrum 0001](Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0001/0002] |
Mycobacterium vaccae(VA-1) (Ref. 0001/0004/0005) Mycobacterium parafortuitum(19686) (Ref. 0001/0004/0005) Mycobacterium diernhoferi(MD-1) (Ref. 0001/0004/0005) Mycobacterium phlei(Ref. 0001/0004/0005) Mycobacterium rhodesiae(RHO-1) (Ref. 0001/0004/0005) Mycobacterium duvalii(Ref. 0004) Mycobacterium gilvum(Ref. 0001) Mycobacterium aurum(Ref. 0004/0005) Mycobacterium kansasii(Ref. 0001/0005) [Table 0001] [Table 0002] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 7 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-dicyclopropanoyl-C57:0 acid |
MMA0007 | Nagatoshi Fujiwara |
C55-diD(b-unit)+C22:0(a-unit) |
C77H150O3 | 1124.013 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0001/0003] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 8 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-dicyclopropanoyl-C58:0 acid |
MMA0008 | Nagatoshi Fujiwara |
C56-diD(b-unit)+C22:0(a-unit) |
C78H152O3 | 1138.040 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0001/0002] |
Mycobacterium parafortuitum(19686) (Ref. 0001/0004/0005) Mycobacterium diernhoferi(MD-1) (Ref. 0004) Mycobacterium phlei(Ref. 0001/0004/0005) Mycobacterium rhodesiae(RHO-1) (Ref. 0001/0004/0005) Mycobacterium vaccae(VA-1) (Ref. 0001/0004/0005) Mycobacterium agri(Ref. 0001) Mycobacterium gilvum(Ref. 0001/0004) Mycobacterium aurum(Ref. 0004/0005) Mycobacterium thermoresistibile(Ref. 0001) Mycobacterium pulveris(Ref. 0004) Mycobacterium kansasii(Ref. 0001/0005) [Table 0001] [Table 0002] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 9 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-dicyclopropanoyl-C59:0 acid |
MMA0009 | Nagatoshi Fujiwara |
C57-diD(b-unit)+C22:0(a-unit) |
C79H154O3 | 1152.066 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0001/0003] |
Mycobacterium phlei(Ref. 0001/0004/0005) Mycobacterium agri(90012) (Ref. 0001) Mycobacterium aurum(Ref. 0005) [Table 0001] [Table 0002] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 10 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-dicyclopropanoyl-C60:0 acid |
MMA0010 | Nagatoshi Fujiwara |
C58-diD(b-unit)+C22:0(a-unit) |
C80H156O3 | 1166.093 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0001/0002] |
Mycobacterium vaccae(VA-1) (Ref. 0005) Mycobacterium aurum(AU-1) (Ref. 0005) Mycobacterium thermoresistibile(Ref. 0001/0004/0005) [Table 0001] [Table 0002] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 11 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Docosanoyl,3-hydroxy-dicyclopropanoyl-C50:0 acid |
MMA0011 | Nagatoshi Fujiwara |
C48-diD(b-unit)+C24:0(a-unit) |
C72H140O3 | 1053.880 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+) [Spectrum 0002](Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0001/0004] |
Mycobacterium vaccae(VA-1) (Ref. 0004/0005) Mycobacterium rhodesiae(Ref. 0001/0005) Mycobacterium marinum(Ref. 0005) Mycobacterium gordonae(Ref. 0005) Mycobacterium phlei(Ref. 0005) [Table 0001] [Table 0002] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
|||||||||||||
| 12 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Docosanoyl,3-hydroxy-dicyclopropanoyl-C51:0 acid |
MMA0012 | Nagatoshi Fujiwara |
C49-diD(b-unit)+C24:0(a-unit) |
C73H142O3 | 1067.907 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
|||||||||||||||
| 13 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Docosanoyl,3-hydroxy-dicyclopropanoyl-C52:0 acid |
MMA0013 | Nagatoshi Fujiwara |
C50-diD(b-unit)+C24:0(a-unit) |
C74H144O3 | 1081.933 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+) [Spectrum 0003](Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0001/0004] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001), C71(Ref. 0004) |
||||||||||||||
| 14 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Docosanoyl,3-hydroxy-dicyclopropanoyl-C53:0 acid |
MMA0014 | Nagatoshi Fujiwara |
C51-diD(b-unit)+C24:0(a-unit) |
C75H146O3 | 1095.960 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
|||||||||||||||
| 15 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Docosanoyl,3-hydroxy-dicyclopropanoyl-C54:0 acid |
MMA0015 | Nagatoshi Fujiwara |
C52-diD(b-unit)+C24:0(a-unit) |
C76H148O3 | 1109.987 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+) [Spectra 0001/0004](Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0001/0004] |
Mycobacterium vaccae(VA-1) (Ref. 0001/0004/0005) Mycobacterium rhodesiae(RHO-1) (Ref. 0001/0004/0005) Mycobacterium phlei(Ref. 0001/0004/0005) Mycobacterium marinum(Ref. 0004/0005) Mycobacterium gordonae(Ref. 0004) Mycobacterium duvalii(Ref. 0004) Mycobacterium gilvum (Ref. 0001) Mycobacterium aurum(Ref. 0004/0005) Mycobacterium diernhoferi (Ref. 0001/0005) Mycobacterium kansasii(Ref. 0001/0005) Mycobacterium bovis(Ref. 0001) Mycobacterium tuberculosis(Ref. 0001) Mycobacterium ulcerans(Ref. 0004) [Table 0001] [Table 0002] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
|||||||||||||
| 16 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Docosanoyl,3-hydroxy-dicyclopropanoyl-C55:0 acid |
MMA0016 | Nagatoshi Fujiwara |
C53-diD(b-unit)+C24:0(a-unit) |
C77H150O3 | 1124.013 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+) [Spectrum 0004](Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
||||||||||||||
| 17 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Docosanoyl,3-hydroxy-dicyclopropanoyl-C56:0 acid |
MMA0017 | Nagatoshi Fujiwara |
C54-diD(b-unit)+C24:0(a-unit) |
C78H152O3 | 1138.040 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+) [Spectrum 0005](Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0001/0004] |
Mycobacterium vaccae(VA-1) (Ref. 0001/0004/0005) Mycobacterium rhodesiae(RHO-1) (Ref. 0001/0004/0005) Mycobacterium phlei(Ref. 0001/0004/0005) Mycobacterium marinum(Ref. 0005) Mycobacterium gordonae(Ref. 0004/0005) Mycobacterium agri(Ref. 0001/0004/0005) Mycobacterium gilvum(Ref. 0001/0004) Mycobacterium pulveris(Ref. 0004) Mycobacterium thermoresistible(Ref. 0001/0004/0005) Mycobacterium aurum (Ref. 0004/0005) Mycobacterium parafortuitum(Ref. 0001) Mycobacterium intracellulare(Ref. 0001) Mycobacterium kansasii(Ref. 0001/0005) Mycobacterium bovis(Ref. 0001) Mycobacterium tuberculosis(Ref. 0001) [Table 0001] [Table 0002] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
|||||||||||||
| 18 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Docosanoyl,3-hydroxy-dicyclopropanoyl-C57:0 acid |
MMA0018 | Nagatoshi Fujiwara |
C55-diD(b-unit)+C24:0(a-unit) |
C79H154O3 | 1152.066 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+) [Spectrum 0005](Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
Mycobacterium agri(Ref. 0005) Mycobacterium thermoresistibile(Ref. 0005) Mycobacterium intracellulare(Ref. 0005) Mycobacterium kansasii(Lab.) (Ref. 0005) Mycobacterium marinum(Ref. 0005) Mycobacterium aurum(Ref. 0005) Mycobacterium phlei(Ref. 0001/0004/0005) Mycobacterium gordonae(Ref. 0005) [Table 0001] [Table 0002] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
|||||||||||||
| 19 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Docosanoyl,3-hydroxy-dicyclopropanoyl-C58:0 acid |
MMA0019 | Nagatoshi Fujiwara |
C56-diD(b-unit)+C24:0(a-unit) |
C80H156O3 | 1166.093 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+) [Spectrum 0006](Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0001/0004] |
Mycobacterium agri(Ref. 0001/0004/0005) Mycobacterium aurum(Ref. 0005) Mycobacterium thermoresistibile(Ref. 0001/0004/0005) Mycobacterium phlei(Ref. 0004) Mycobacterium intracellulare(Ref. 0001/0004/0005) Mycobacterium kansasii(Lab.) (Ref. 0001/0004) Mycobacterium marinum(Ref. 0005) Mycobacterium gordonae(Ref. 0005) Mycobacterium gilvum(Ref. 0001) Mycobacterium avium(Ref. 0004/0005) Mycobacterium bovis(Ref. 0001) Mycobacterium tuberculosis(Ref. 0001) [Table 0001] [Table 0002] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
|||||||||||||
| 20 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Docosanoyl,3-hydroxy-dicyclopropanoyl-C60:0 acid |
MMA0020 | Nagatoshi Fujiwara |
C58-diD(b-unit)+C24:0(a-unit) |
C82H160O3 | 1194.146 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+) [Spectrum 0007](Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0001/0004] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 21 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Tetracosanoyl,3-hydroxy-dicyclopropanoyl-C50:0 acid |
MMA0021 | Nagatoshi Fujiwara |
C48-diD(b-unit)+C26:0(a-unit) |
C74H144O3 | 1081.933 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 22 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Tetracosanoyl,3-hydroxy-dicyclopropanoyl-C51:0 acid |
MMA0022 | Nagatoshi Fujiwara |
C49-diD(b-unit)+C26:0(a-unit) |
C75H146O3 | 1095.960 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 23 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Tetracosanoyl,3-hydroxy-dicyclopropanoyl-C52:0 acid |
MMA0023 | Nagatoshi Fujiwara |
C50-diD(b-unit)+C26:0(a-unit) |
C76H148O3 | 1109.987 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 24 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Tetracosanoyl,3-hydroxy-dicyclopropanoyl-C53:0 acid |
MMA0024 | Nagatoshi Fujiwara |
C51-diD(b-unit)+C26:0(a-unit) |
C77H150O3 | 1124.013 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 25 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Tetracosanoyl,3-hydroxy-dicyclopropanoyl-C54:0 acid |
MMA0025 | Nagatoshi Fujiwara |
C52-diD(b-unit)+C26:0(a-unit) |
C78H152O3 | 1138.040 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 26 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Tetracosanoyl,3-hydroxy-dicyclopropanoyl-C55:0 acid |
MMA0026 | Nagatoshi Fujiwara |
C53-diD(b-unit)+C26:0(a-unit) |
C79H154O3 | 1152.066 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 27 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Tetracosanoyl,3-hydroxy-dicyclopropanoyl-C56:0 acid |
MMA0027 | Nagatoshi Fujiwara |
C54-diD(b-unit)+C26:0(a-unit) |
C80H156O3 | 1166.093 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 28 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Tetracosanoyl,3-hydroxy-dicyclopropanoyl-C57:0 acid |
MMA0028 | Nagatoshi Fujiwara |
C55-diD(b-unit)+C26:0(a-unit) |
C81H158O3 | 1180.119 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 29 |  |
Dicyclopropanoyl-a-mycolic acid |
2-Tetracosanoyl,3-hydroxy-dicyclopropanoyl-C58:0 acid |
MMA0029 | Nagatoshi Fujiwara |
C56-diD(b-unit)+C26:0(a-unit) |
C82H160O3 | 1194.146 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52 were existed in Mycobacterium microti(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) |
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| 30 |  |
Monoenoic,monocyclopropanoyl-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-monocyclopropanoyl-C49:1 acid |
MMA0030 | Nagatoshi Fujiwara |
C47:1(monoD)(b-unit)+C22:0(a-unit) |
C69H134O3 | 1011.800 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
Mycobacterium diernhoferi(Ref. 0005) |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) a mycolic acid was existed in Mycobacterium fortuitum, Mycobacterium peregvium and Mycobacterium smegmatis.(Ref. 0006) |
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| 31 |  |
Monoenoic,monocyclopropanoyl-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-monocyclopropanoyl-C51:1 acid |
MMA0031 | Nagatoshi Fujiwara |
C49:1(monoD)(b-unit)+C22:0(a-unit) |
C71HH138O3 | 1040.862 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 32 |  |
Monoenoic,monocyclopropanoyl-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-monocyclopropanoyl-C53:1 acid |
MMA0032 | Nagatoshi Fujiwara |
C51:1(monoD)(b-unit)+C22:0(a-unit) |
C73HH142O3 | 1068.915 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 33 |  |
Monoenoic,monocyclopropanoyl-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-monocyclopropanoyl-C55:1 acid |
MMA0033 | Nagatoshi Fujiwara |
C53:1(monoD)(b-unit)+C22:0(a-unit) |
C75HH146O3 | 1096.968 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 34 |  |
Monoenoic,monocyclopropanoyl-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-monocyclopropanoyl-C57:1 acid |
MMA0034 | Nagatoshi Fujiwara |
C55:1(monoD)(b-unit)+C22:0(a-unit) |
C77HH150O3 | 1125.021 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 35 |  |
Monoenoic,monocyclopropanoyl-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-monocyclopropanoyl-C59:1 acid |
MMA0035 | Nagatoshi Fujiwara |
C57:1(monoD)(b-unit)+C22:0(a-unit) |
C79HH154O3 | 1153.074 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 36 |  |
Monoenoic,monocyclopropanoyl-a-mycolic acid |
2-Docosanoyl,3-hydroxy-monocyclopropanoyl-C51:1 acid |
MMA0036 | Nagatoshi Fujiwara |
C49:1(monoD)(b-unit)+C24:0(a-unit) |
C73H142O3 | 1067.907 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 37 |  |
Monoenoic,monocyclopropanoyl-a-mycolic acid |
2-Docosanoyl,3-hydroxy-monocyclopropanoyl-C53:1 acid |
MMA0037 | Nagatoshi Fujiwara |
C51:1(monoD)(b-unit)+C24:0(a-unit) |
C75H146O3 | 1095.960 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 38 |  |
Monoenoic,monocyclopropanoyl-a-mycolic acid |
2-Docosanoyl,3-hydroxy-monocyclopropanoyl-C55:1 acid |
MMA0038 | Nagatoshi Fujiwara |
C53:1(monoD)(b-unit)+C24:0(a-unit) |
C77H150O3 | 1124.013 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+) [Spectrum 0008](Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 39 |  |
Monoenoic,monocyclopropanoyl-a-mycolic acid |
2-Docosanoyl,3-hydroxy-monocyclopropanoyl-C57:1 acid |
MMA0039 | Nagatoshi Fujiwara |
C55:1(monoD)(b-unit)+C24:0(a-unit) |
C79H154O3 | 1152.066 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 40 |  |
Monomethyl,monocyclopropanoyl,monoenoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy,monomethyl-monocyclopropanoyl-C51:1 acid |
MMA0040 | Nagatoshi Fujiwara |
CH3-C49:1(monoD)(b-unit)+C22:0(a-unit) |
C72H140O3 | 1053.880 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 41 |  |
Monomethyl,monocyclopropanoyl,monoenoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy,monomethyl-monocyclopropanoyl-C53:1 acid |
MMA0041 | Nagatoshi Fujiwara |
CH3-C51:1(monoD)(b-unit)+C22:0(a-unit) |
C74H144O3 | 1081.933 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 42 |  |
Monomethyl,monocyclopropanoyl,monoenoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy,monomethyl-monocyclopropanoyl-C55:1 acid |
MMA0042 | Nagatoshi Fujiwara |
CH3-C53:1(monoD)(b-unit)+C22:0(a-unit) |
C76H148O3 | 1109.987 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
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| 43 |  |
Monomethyl,monocyclopropanoyl,monoenoic-a-mycolic acid |
2-Ecosanoyl,3-hydroxy,monomethyl-monocyclopropanoyl-C57:1 acid |
MMA0043 | Nagatoshi Fujiwara |
CH3-C55:1(monoD)(b-unit)+C22:0(a-unit) |
C78H152O3 | 1138.040 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
|||||||||||||||
| 44 |  |
Monomethyl,monocyclopropanoyl,monoenoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy,monomethyl-monocyclopropanoyl-C59:1 acid |
MMA0044 | Nagatoshi Fujiwara |
CH3-C57:1(monoD)(b-unit)+C22:0(a-unit) |
C80H156O3 | 1166.093 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
Mycobacterium phlei(Ref. 0004) |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
||||||||||||||
| 45 |  |
Monomethyl,monocyclopropanoyl,monoenoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy,monomethyl-monocyclopropanoyl-C49:1 acid |
MMA0045 | Nagatoshi Fujiwara |
CH3-C47:1(monoD)(b-unit)+C24:0(a-unit) |
C72H140O3 | 1053.880 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
|||||||||||||||
| 46 |  |
Monomethyl,monocyclopropanoyl,monoenoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy,monomethyl-monocyclopropanoyl-C51:1 acid |
MMA0046 | Nagatoshi Fujiwara |
CH3-C49:1(monoD)(b-unit)+C24:0(a-unit) |
C74H144O3 | 1081.933 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
|||||||||||||||
| 47 |  |
Monomethyl,monocyclopropanoyl,monoenoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy,monomethyl-monocyclopropanoyl-C53:1 acid |
MMA0047 | Nagatoshi Fujiwara |
CH3-C51:1(monoD)(b-unit)+C24:0(a-unit) |
C76H148O3 | 1109.987 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
|||||||||||||||
| 48 |  |
Monomethyl,monocyclopropanoyl,monoenoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy,monomethyl-monocyclopropanoyl-C55:1 acid |
MMA0048 | Nagatoshi Fujiwara |
CH3-C53:1(monoD)(b-unit)+C24:0(a-unit) |
C78H152O3 | 1138.040 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
|||||||||||||||
| 49 |  |
Monomethyl,monocyclopropanoyl,monoenoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy,monomethyl-monocyclopropanoyl-C57:1 acid |
MMA0049 | Nagatoshi Fujiwara |
CH3-C55:1(monoD)(b-unit)+C24:0(a-unit) |
C80H156O3 | 1166.093 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
Mycobacterium phlei(Ref. 0004) |
DiD mycolic acids were existed in Mycobacterium tuberculosis.(Ref. 0011) a-unit, C24:0,C26:0; carbon chain length, L=17,18,19, M=10, N=15,17,19,21(Ref. 0016) a-unit, C26:0; carbon chain length C84(Ref. 0005) DiD mycolic acids were existed in Mycobacterium microti. a-unit, C26:0; carbon chain length, L+M+N=42,44,46,48,50,52(Ref. 0008) DiD mycolic acids (C80H156O3) were existed in Mycobacterium kansaii.(Ref. 0017) DiD mycolic acids were existed in Mycobacterium diernhoferi. a-unit, C22:0; carbon chain length C70(Ref. 0001),C71(Ref. 0004) It is reported that Mycobacterium phlei has mycolic acids with carbon chain length with C72,74,76,77,78,79,80 as diene(Ref. 0014), with C70,72,74,76,77,78,80 as diene(Ref. 0010) Increasing growth temperature resulted in an increase in longer chain species of mycolic acids with a concomitant decrease in shorter chain homologoues.(Ref. 0010/0014) |
||||||||||||||
| 50 |  |
(Corynomycolic acid) Saturated-a-mycolic acid |
2-Dodecanoyl,3-hydroxy-octanoic acid |
MMA0050 | Nagatoshi Fujiwara |
C6:0(b-unit)+C14:0(a-unit) |
C20H40O3 | 328.530 | |
Chloroform,n-Hexane |
A:[CH3-(CH2)m-CH-O-TMS] B:[-CH(-O-TMS)-CH(CO-O-CH3)-(CH2)n-CH3] (m=4 to 14, n=11 or 13) |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage) (Ref. 0027) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 |
Corynebacterium ulcerans(Ref. 0027) |
The composition of mycolic acid in Corynebacterium diphtheriae. Carbon chain length C30,32 (70%), C24,26,28,34 (trace), odd-numbered carbon chain length (3%) (Ref. 0026) Mycobacterium leprosy isolated from human has C24-36 mycolic acids with 0-4 double bonds.(Ref. 0026) Isoniazide inhibits the synsesis of mycolic acid in sensitive strain.(Ref. 0019) |
|||||||||||||
| 51 |  |
(Corynomycolic acid) Saturated-a-mycolic acid |
2-Dodecanoyl,3-hydroxy-decanoic acid |
MMA0051 | Nagatoshi Fujiwara |
C8:0(b-unit)+C14:0(a-unit) |
C22H44O3 | 356.583 | |
Chloroform,n-Hexane |
A:[CH3-(CH2)m-CH-O-TMS] B:[-CH(-O-TMS)-CH(CO-O-CH3)-(CH2)n-CH3] (m=4 to 14, n=11 or 13) |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage) [Spectrum 0009](Ref. 0027) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 |
Corynebacterium ulcerans(Ref. 0027) |
The composition of mycolic acid in Corynebacterium diphtheriae. Carbon chain length C30,32 (70%), C24,26,28,34 (trace), odd-numbered carbon chain length (3%) (Ref. 0026) Mycobacterium leprosy isolated from human has C24-36 mycolic acids with 0-4 double bonds.(Ref. 0026) Isoniazide inhibits the synsesis of mycolic acid in sensitive strain.(Ref. 0019) |
|||||||||||||
| 52 |  |
(Corynomycolic acid) Saturated-a-mycolic acid |
2-Dodecanoyl,3-hydroxy-tetradecanoic acid |
MMA0052 | Nagatoshi Fujiwara |
C12:0(b-unit)+C14:0(a-unit) |
C26H52O3 | 412.689 | |
Chloroform,n-Hexane |
A:[CH3-(CH2)m-CH-O-TMS] B:[-CH(-O-TMS)-CH(CO-O-CH3)-(CH2)n-CH3] (m=4 to 14, n=11 or 13) |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage) [Spectrum 0010](Ref. 0027) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 |
Corynebacterium ulcerans(Ref. 0027) |
The composition of mycolic acid in Corynebacterium diphtheriae. Carbon chain length C30,32 (70%), C24,26,28,34 (trace), odd-numbered carbon chain length (3%) (Ref. 0026) Mycobacterium leprosy isolated from human has C24-36 mycolic acids with 0-4 double bonds.(Ref. 0026) Isoniazide inhibits the synsesis of mycolic acid in sensitive strain.(Ref. 0019) |
|||||||||||||
| 53 |  |
(Corynomycolic acid) Saturated-a-mycolic acid |
2-Dodecanoyl,3-hydroxy-hexadecanoic acid |
MMA0053 | Nagatoshi Fujiwara |
C14:0(b-unit)+C14:0(a-unit) |
C28H56O3 | 440.742 | |
Chloroform,n-Hexane |
A:[CH3-(CH2)m-CH-O-TMS] B:[-CH(-O-TMS)-CH(CO-O-CH3)-(CH2)n-CH3] (m=4 to 14, n=11 or 13) |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage) (Ref. 0027) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 |
Corynebacterium ulcerans(Ref. 0027) |
The composition of mycolic acid in Corynebacterium diphtheriae. Carbon chain length C30,32 (70%), C24,26,28,34 (trace), odd-numbered carbon chain length (3%) (Ref. 0026) Mycobacterium leprosy isolated from human has C24-36 mycolic acids with 0-4 double bonds.(Ref. 0026) Isoniazide inhibits the synsesis of mycolic acid in sensitive strain.(Ref. 0019) |
|||||||||||||
| 54 |  |
(Corynomycolic acid) Saturated-a-mycolic acid |
2-Tetradecanoyl,3-hydroxy-decanoic acid |
MMA0054 | Nagatoshi Fujiwara |
C8:0(b-unit)+C16:0(a-unit) |
C24H48O3 | 384.636 | |
Chloroform,n-Hexane |
A:[CH3-(CH2)m-CH-O-TMS] B:[-CH(-O-TMS)-CH(CO-O-CH3)-(CH2)n-CH3] (m=4 to 14, n=11 or 13) |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage) (Ref. 0027) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 |
Corynebacterium ulcerans(Ref. 0027) |
The composition of mycolic acid in Corynebacterium diphtheriae. Carbon chain length C30,32 (70%), C24,26,28,34 (trace), odd-numbered carbon chain length (3%) (Ref. 0026) Mycobacterium leprosy isolated from human has C24-36 mycolic acids with 0-4 double bonds.(Ref. 0026) Isoniazide inhibits the synsesis of mycolic acid in sensitive strain.(Ref. 0019) |
|||||||||||||
| 55 |  |
(Corynomycolic acid) Saturated-a-mycolic acid |
2-Tetradecanoyl,3-hydroxy-dodecanoic acid |
MMA0055 | Nagatoshi Fujiwara |
C10:0(b-unit)+C16:0(a-unit) |
C26H52O3 | 412.689 | |
Chloroform,n-Hexane |
A:[CH3-(CH2)m-CH-O-TMS] B:[-CH(-O-TMS)-CH(CO-O-CH3)-(CH2)n-CH3] (m=4 to 14, n=11 or 13) |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage) [Spectrum 0010](Ref. 0027) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 |
Corynebacterium ulcerans(Ref. 0027) |
The composition of mycolic acid in Corynebacterium diphtheriae. Carbon chain length C30,32 (70%), C24,26,28,34 (trace), odd-numbered carbon chain length (3%) (Ref. 0026) Mycobacterium leprosy isolated from human has C24-36 mycolic acids with 0-4 double bonds.(Ref. 0026) Isoniazide inhibits the synsesis of mycolic acid in sensitive strain.(Ref. 0019) |
|||||||||||||
| 56 |  |
(Corynomycolic acid) Saturated-a-mycolic acid |
2-Tetradecanoyl,3-hydroxy-tetradecanoic acid |
MMA0056 | Nagatoshi Fujiwara |
C12:0(b-unit)+C16:0(a-unit) |
C28H56O3 | 440.742 | |
Chloroform,n-Hexane |
A:[CH3-(CH2)m-CH-O-TMS] B:[-CH(-O-TMS)-CH(CO-O-CH3)-(CH2)n-CH3] (m=4 to 14, n=11 or 13) |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage) (Ref. 0027) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 |
Corynebacterium ulcerans(Ref. 0027) |
The composition of mycolic acid in Corynebacterium diphtheriae. Carbon chain length C30,32 (70%), C24,26,28,34 (trace), odd-numbered carbon chain length (3%) (Ref. 0026) Mycobacterium leprosy isolated from human has C24-36 mycolic acids with 0-4 double bonds.(Ref. 0026) Isoniazide inhibits the synsesis of mycolic acid in sensitive strain.(Ref. 0019) |
|||||||||||||
| 57 |  |
(Corynomycolic acid) Saturated-a-mycolic acid |
2-Tetradecanoyl,3-hydroxy-hexadecanoic acid |
MMA0057 | Nagatoshi Fujiwara |
C14:0(b-unit)+C16:0(a-unit) |
C30H60O3 | 468.796 | |
Chloroform,n-Hexane |
A:[CH3-(CH2)m-CH-O-TMS] B:[-CH(-O-TMS)-CH(CO-O-CH3)-(CH2)n-CH3] (m=4 to 14, n=11 or 13) |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage) [Spectrum 0011](Ref. 0027) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 |
Corynebacterium ulcerans(Ref. 0027) |
The composition of mycolic acid in Corynebacterium diphtheriae. Carbon chain length C30,32 (70%), C24,26,28,34 (trace), odd-numbered carbon chain length (3%) (Ref. 0026) Mycobacterium leprosy isolated from human has C24-36 mycolic acids with 0-4 double bonds.(Ref. 0026) Isoniazide inhibits the synsesis of mycolic acid in sensitive strain.(Ref. 0019) |
|||||||||||||
| 58 |  |
(Corynomycolic acid) Saturated-a-mycolic acid |
2-Tetradecanoyl,3-hydroxy-octadecanoic acid |
MMA0058 | Nagatoshi Fujiwara |
C16:0(b-unit)+C16:0(a-unit) |
C32H64O3 | 496.849 | |
Chloroform,n-Hexane |
A:[CH3-(CH2)m-CH-O-TMS] B:[-CH(-O-TMS)-CH(CO-O-CH3)-(CH2)n-CH3] (m=4 to 14, n=11 or 13) |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage) [Spectrum 0012](Ref. 0027) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 |
Corynebacterium ulcerans(Ref. 0027) |
The composition of mycolic acid in Corynebacterium diphtheriae. Carbon chain length C30,32 (70%), C24,26,28,34 (trace), odd-numbered carbon chain length (3%) (Ref. 0026) Mycobacterium leprosy isolated from human has C24-36 mycolic acids with 0-4 double bonds.(Ref. 0026) Isoniazide inhibits the synsesis of mycolic acid in sensitive strain.(Ref. 0019) |
|||||||||||||
| 59 |  |
Monoenoic-a-mycolic acid |
2-Dodecanoyl,3-hydroxy-tetradecanoic acid(C14:1) (or C16:1, C18:1) |
MMA0059 | Nagatoshi Fujiwara |
C12:1(b-unit)+C14:0(a-unit) |
C26H50O3 | 410.673 | |
Chloroform,n-Hexane |
A:[CH3-(CH2)m-CH-O-TMS] B:[-CH(-O-TMS)-CH(CO-O-CH3)-(CH2)n-CH3] (m=4 to 14, n=11 or 13) |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage) (Ref. 0027) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 |
Corynebacterium ulcerans(Ref. 0027) |
The composition of mycolic acid in Corynebacterium diphtheriae. Carbon chain length C30,32 (70%), C24,26,28,34 (trace), odd-numbered carbon chain length (3%) (Ref. 0026) Mycobacterium leprosy isolated from human has C24-36 mycolic acids with 0-4 double bonds.(Ref. 0026) Isoniazide inhibits the synsesis of mycolic acid in sensitive strain.(Ref. 0019) |
|||||||||||||
| 60 |  |
Monoenoic-a-mycolic acid |
2-Tetradecanoyl,3-hydroxy-dodecenoic acid(C12:1) (or C14:1, 16:1, 18:1) |
MMA0060 | Nagatoshi Fujiwara |
C10:1(b-unit)+C16:0(a-unit) |
C26H50O3 | 410.673 | |
Chloroform,n-Hexane |
A:[CH3-(CH2)m-CH-O-TMS] B:[-CH(-O-TMS)-CH(CO-O-CH3)-(CH2)n-CH3] (m=4 to 14, n=11 or 13) |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage) (Ref. 0027) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 |
Corynebacterium ulcerans(Ref. 0027) |
The composition of mycolic acid in Corynebacterium diphtheriae. Carbon chain length C30,32 (70%), C24,26,28,34 (trace), odd-numbered carbon chain length (3%) (Ref. 0026) Mycobacterium leprosy isolated from human has C24-36 mycolic acids with 0-4 double bonds.(Ref. 0026) Isoniazide inhibits the synsesis of mycolic acid in sensitive strain.(Ref. 0019) |
|||||||||||||
| 61 |  |
Dienoic-a-mycolic acid |
2-Tetradecanoyl,3-hydroxy-C18:2 acid |
MMA0061 | Nagatoshi Fujiwara |
C16:2(b-unit)+C16:0(a-unit) |
C32H60O3 | 492.817 | |
Chloroform,n-Hexane |
A:[CH3-(CH2)m-CH-O-TMS] B:[-CH(-O-TMS)-CH(CO-O-CH3)-(CH2)n-CH3] (m=4 to 14, n=11 or 13) |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage) (Ref. 0027) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 |
Corynebacterium ulcerans(Ref. 0027) |
The composition of mycolic acid in Corynebacterium diphtheriae. Carbon chain length C30,32 (70%), C24,26,28,34 (trace), odd-numbered carbon chain length (3%) (Ref. 0026) Mycobacterium leprosy isolated from human has C24-36 mycolic acids with 0-4 double bonds.(Ref. 0026) Isoniazide inhibits the synsesis of mycolic acid in sensitive strain.(Ref. 0019) |
|||||||||||||
| 62 |  |
Monoenoic-a-mycolic acid |
2-Hexadecanoyl,3-hydroxy-C44:1 acid (or C46:1, C48:1, C50:1) |
MMA0062 | Nagatoshi Fujiwara |
C42:1(b-unit)+C18:0(a-unit) |
C60H118O3 | 887.577 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 63 |  |
Monoenoic-a-mycolic acid |
2-Octadecanoyl,3-hydroxy-C42:1 acid (or C44:1, C46:1, C50:1, C52:1 acid) |
MMA0063 | Nagatoshi Fujiwara |
C40:1(b-unit)+C20:0(a-unit) |
C60H118O3 | 887.577 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 64 |  |
Monoenoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-C44:1 acid (or C46:1, C48:1, C50:1, C52:1) |
MMA0064 | Nagatoshi Fujiwara |
C42:1(b-unit)+C22:0(a-unit) |
C64H126O3 | 943.683 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 65 |  |
Dienoic-a-mycolic acid |
2-Hexadecanoyl,3-hydroxy-C46:2 acid (or C48:2, C50:2, C52:2, C54:2) |
MMA0065 | Nagatoshi Fujiwara |
C44:2(b-unit)+C18:0(a-unit) |
C62H120O3 | 913.614 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 66 |  |
Dienoic-a-mycolic acid |
2-Octadecanoyl,3-hydroxy-C44:2 acid (or C46:2, C48:2, C50:2, C52:2, C54:2) |
MMA0066 | Nagatoshi Fujiwara |
C42:2(b-unit)+C20:0(a-unit) |
C62H120O3 | 913.614 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 67 |  |
Dienoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-C44:2 acid (or C46:2, C48:2, C50:2, C52:2, C54:2) |
MMA0067 | Nagatoshi Fujiwara |
C42:2(b-unit)+C22:0(a-unit) |
C64H124O3 | 941.668 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 68 |  |
Dienoic-a-mycolic acid |
2-Octadecenoyl,3-hydroxy-C46:1 acid (or C48:1, C50:1, C52:1, C54:1) |
MMA0068 | Nagatoshi Fujiwara |
C44:1(b-unit)+C20:1(a-unit) |
C64H124O3 | 941.668 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 69 |  |
Dienoic-a-mycolic acid |
2-Octadecenoyl,3-hydroxy-C44:1 acid (or C46:1, C48:1, C50:1, C52:1, C54:1) |
MMA0069 | Nagatoshi Fujiwara |
C42:1(b-unit)+C20:1(a-unit) |
C62H120O3 | 913.614 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 70 |  |
Trienoic-a-mycolic acid |
2-Hexadecanoyl,3-hydroxy-C48:3 acid (or C50:3, C52:3, C54:3) |
MMA0070 | Nagatoshi Fujiwara |
C46:3(b-unit)+C18:0(a-unit) |
C64H122O3 | 939.652 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0013](Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 71 |  |
Trienoic-a-mycolic acid |
2-Octadecanoyl,3-hydroxy-C46:3 acid (or C48:3, C50:3, C52:3, C54:3, C56:3) |
MMA0071 | Nagatoshi Fujiwara |
C44:3(b-unit)+C20:0(a-unit) |
C64H122O3 | 939.652 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0013](Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 72 |  |
Trienoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-C46:3 acid (or C48:3, C50:3, C52:3, C54:3) |
MMA0072 | Nagatoshi Fujiwara |
C44:3(b-unit)+C22:0(a-unit) |
C66H126O3 | 967.705 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 73 |  |
Trienoic-a-mycolic acid |
2-Octadecenoyl,3-hydroxy-C48:2 acid (or C50:2, C52:2, C54:2) |
MMA0073 | Nagatoshi Fujiwara |
C46:2(b-unit)+C20:1(a-unit) |
C66H126O3 | 967.705 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 74 |  |
Trienoic-a-mycolic acid |
2-Eicosenoyl,3-hydroxy-C46:2 acid (or C48:2, C50:2, C52:2, C54:2) |
MMA0074 | Nagatoshi Fujiwara |
C44:2(b-unit)+C22:1(a-unit) |
C66H126O3 | 967.705 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 75 |  |
Tetraenoic-a-mycolic acid |
2-Hexadecanoyl,3-hydroxy-C50:4 acid (or C52:4) |
MMA0075 | Nagatoshi Fujiwara |
C48:4(b-unit)+C18:0(a-unit) |
C66H124O3 | 965.689 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0014](Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 76 |  |
Tetraenoic-a-mycolic acid |
2-Octadecanoyl,3-hydroxy-C48:4 acid (or C50:4, C52:4, C54:4, C56:4, C58:4) |
MMA0076 | Nagatoshi Fujiwara |
C46:4(b-unit)+C20:0(a-unit) |
C66H124O3 | 965.689 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 77 |  |
Tetraenoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-C48:4 acid (or C50:4, C52:4, C54:4, C56:4) |
MMA0077 | Nagatoshi Fujiwara |
C46:4(b-unit)+C22:0(a-unit) |
C68H128O3 | 993.742 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0015](Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 78 |  |
Tetraenoic-a-mycolic acid |
2-Octadecenoyl,3-hydroxy-C48:3 acid (or C50:3, C52:3, C54:3, C56:3) |
MMA0078 | Nagatoshi Fujiwara |
C46:3(b-unit)+C20:1(a-unit) |
C66H124O3 | 965.689 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0014](Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 79 |  |
Tetraenoic-a-mycolic acid |
2-Eicosenoyl,3-hydroxy-C48:3 acid (or C50:3, C52:3, C54:3, C56:3) |
MMA0079 | Nagatoshi Fujiwara |
C46:3(b-unit)+C22:1(a-unit) |
C68H128O3 | 993.742 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0015](Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 80 |  |
Pentaenoic-a-mycolic acid |
2-Octadecanoyl,3-hydroxy-C52:5 acid (or C54:5, C56:5) |
MMA0080 | Nagatoshi Fujiwara |
C50:5(b-unit)+C20:0(a-unit) |
C70H130O3 | 1019.779 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 81 |  |
Pentaenoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-C50:5 acid (or C52:5, C54:5, C56:5) |
MMA0081 | Nagatoshi Fujiwara |
C48:5(b-unit)+C22:0(a-unit) |
C70H130O3 | 1019.779 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 82 |  |
Pentaenoic-a-mycolic acid |
2-Octadecenoyl,3-hydroxy-C52:4 acid (or C54:4, C56:4) |
MMA0082 | Nagatoshi Fujiwara |
C50:4(b-unit)+C20:1(a-unit) |
C70H130O3 | 1019.779 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 83 |  |
Pentaenoic-a-mycolic acid |
2-Eicosenoyl,3-hydroxy-C50:4 acid (or C52:4, C54:4, C56:4) |
MMA0083 | Nagatoshi Fujiwara |
C48:4(b-unit)+C22:1(a-unit) |
C70H130O3 | 1019.779 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 84 |  |
Hexaenoic-a-mycolic acid |
2-Octadecanoyl,3-hydroxy-C52:6 acid (or C54:6, C56:6, C58:6) |
MMA0084 | Nagatoshi Fujiwara |
C50:6(b-unit)+C20:0(a-unit) |
C70H128O3 | 1017.764 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 85 |  |
Hexaenoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-C54:6 acid (or C56:6, C58:6) |
MMA0085 | Nagatoshi Fujiwara |
C52:6(b-unit)+C22:0(a-unit) |
C74H136O3 | 1073.870 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 86 |  |
Hexaenoic-a-mycolic acid |
2-Octadecenoyl,3-hydroxy-C52:5 acid (or C54:5, C56:5) |
MMA0086 | Nagatoshi Fujiwara |
C50:5(b-unit)+C20:1(a-unit) |
C70H128O3 | 1017.764 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 87 |  |
Hexaenoic-a-mycolic acid |
2-Eicosenoyl,3-hydroxy-C54:5 acid (or C56:5) |
MMA0087 | Nagatoshi Fujiwara |
C52:5(b-unit)+C22:1(a-unit) |
C74H136O3 | 1073.870 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0016](Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 88 |  |
Heptaenoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-C52:7 acid (or C54:7, C56:7, C58:7) |
MMA0088 | Nagatoshi Fujiwara |
C50:7(b-unit)+C22:0(a-unit) |
C72H130O3 | 1043.801 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 89 |  |
Heptaenoic-a-mycolic acid |
2-Octadecenoyl,3-hydroxy-C54:6 acid (or C56:6, C58:6) |
MMA0089 | Nagatoshi Fujiwara |
C52:6(b-unit)+C20:1(a-unit) |
C72H130O3 | 1043.801 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 90 |  |
Heptaenoic-a-mycolic acid |
2-Eicosenoyl,3-hydroxy-C52:6 acid (or C54:6, C56:6, C58:6) |
MMA0090 | Nagatoshi Fujiwara |
C50:6(b-unit)+C22:1(a-unit) |
C72H130O3 | 1043.801 | |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0024) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0005/0006] |
Gordona aurantiaca has two spotS of mycolic acid in TLC. Upper spot is carbon chain length, C60-78 and 2-7 double bond. Lower spot is C62-74, monoene, diene, triene, tetraene. The mycolic acid composition of Gordona is different from mycobacteria and nocardia.(Ref. 0024)The mycolic acid species of Gordona bronchialis is (a-unit C18:0) C58:0, C58:1 ,C60:1, C62:1, C58:2, C60:2, C62:2, C64:2, C60:3, C62:3, C64:3, C66:3, C62:4, C64:4, C66:4, C68:4, C64:5, C66:5, C68:5(Ref. 0022) |
|||||||||||||||
| 91 |  |
Saturated-a-mycolic acid |
2-Dodecanoyl,3-hydroxy-C38:0 acid (or C40:0) |
MMA0091 | Nagatoshi Fujiwara |
C36:0(b-unit)+C14:0(a-unit) |
C50H100O3 | 749.327 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0020) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0007/0008](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 92 |  |
Saturated-a-mycolic acid |
2-Tetradecanoyl,3-hydroxy-C34:0 acid (or C36:0, C38:0, C40:0, C42:0, C44:0, C46:0) |
MMA0092 | Nagatoshi Fujiwara |
C32:0(b-unit)+C16:0(a-unit) |
C48H96O3 | 721.274 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0020) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0007/0008](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 93 |  |
Saturated-a-mycolic acid |
2-Hexadecanoyl,3-hydroxy-C38:0 acid (or C40:0) |
MMA0093 | Nagatoshi Fujiwara |
C36:0(b-unit)+C16:0(a-unit) |
C52H104O3 | 777.380 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0017](Ref. 0020) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0007/0008](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 94 |  |
Monoenoic-a-mycolic acid |
2-Tetradecanoyl,3-hydroxy-C34:1 acid (or C36:1, C38:1, C40:1, C42:1, C44:1, C46:1) |
MMA0094 | Nagatoshi Fujiwara |
C32:1(b-unit)+C16:0(a-unit) |
C48H94O3 | 719.258 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0020) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0007/0008](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 95 |  |
Monoenoic-a-mycolic acid |
2-Tetradecenoyl,3-hydroxy-C36:0 acid(or C38:0, C40:0) |
MMA0095 | Nagatoshi Fujiwara |
C34:0(b-unit)+C16:1(a-unit) |
C50H98O3 | 747.311 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0020) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0007/0008](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 96 |  |
Dienoic-a-mycolic acid |
2-Tetradecanoyl,3-hydroxy-C34:2 acid (or C36:2, C38:2, C40:2, C42:2, C44:2, C46:2) |
MMA0096 | Nagatoshi Fujiwara |
C32:2(b-unit)+C16:0(a-unit) |
C48H92O3 | 717.242 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0018](Ref. 0020) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0007/0008](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 97 |  |
Dienoic-a-mycolic acid |
2-Tetradecenoyl,3-hydroxy-C36:1 acid (or C38:1, C40:1) |
MMA0097 | Nagatoshi Fujiwara |
C34:1(b-unit)+C16:1(a-unit) |
C50H96O3 | 745.295 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0020) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0007/0008](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 98 |  |
Trienoic-a-mycolic acid |
2-Tetradecanoyl,3-hydroxy-C36:3 acid (or C38:3, C40:3, C42:3, C44:3, C46:3, C48:3) |
MMA0098 | Nagatoshi Fujiwara |
C34:3(b-unit)+C16:0(a-unit) |
C50H94O3 | 743.280 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0020) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0007/0008](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 99 |  |
Trienoic-a-mycolic acid |
2-Dodecanoyl,3-hydroxy-C38:3 acid (or C40:3, C42:3) |
MMA0099 | Nagatoshi Fujiwara |
C36:3(b-unit)+C14:0(a-unit) |
C50H94O3 | 743.280 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0020) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0007/0008](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 100 |  |
Trienoic-a-mycolic acid |
2-Tetradecenoyl,3-hydroxy-C42:2 acid |
MMA0100 | Nagatoshi Fujiwara |
C40:2(b-unit)+C16:1(a-unit) |
C56H106O3 | 827.439 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0019](Ref. 0020) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0007/0008](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 101 |  |
Tetraenoic-a-mycolic acid |
2-Tetradecanoyl,3-hydroxy-C38:4 acid (or C40:4, C42:4, C44:4) |
MMA0101 | Nagatoshi Fujiwara |
C36:4(b-unit)+C16:0(a-unit) |
C52H96O3 | 769.317 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0020](Ref. 0020) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0007/0008](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 102 |  |
Tetraenoic-a-mycolic acid |
2-Tetradecenoyl,3-hydroxy-C38:3 acid (or C40:3, C42:3, C44:3) |
MMA0102 | Nagatoshi Fujiwara |
C36:3(b-unit)+C16:1(a-unit) |
C52H96O3 | 769.317 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0020](Ref. 0020) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0007/0008](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 103 |  |
Saturated-a-mycolic acid |
2-Octanoyl,3-hydroxy-tetracosanoic acid |
MMA0103 | Nagatoshi Fujiwara |
C22:0(b-unit)+C10:0(a-unit) |
C32H64O3 | 496.849 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0021](Ref. 0023) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0009](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 104 |  |
Saturated-a-mycolic acid |
2-Nonanoyl,3-hydroxy-tetracosanoic acid |
MMA0104 | Nagatoshi Fujiwara |
C22:0(b-unit)+C11:0(a-unit) |
C33H66O3 | 510.875 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0023) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0009](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 105 |  |
Saturated-a-mycolic acid |
2-Decanoyl,3-hydroxy-docosanoic acid (or C23:0, C24:0, C25:0, C26:0) |
MMA0105 | Nagatoshi Fujiwara |
C20:0(b-unit)+C10:0(a-unit) |
C30H60O3 | 468.796 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0023) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0009](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 106 |  |
Saturated-a-mycolic acid |
2-Undecanoyl,3-hydroxy-tetracosanoic acid |
MMA0106 | Nagatoshi Fujiwara |
C22:0(b-unit)+C13:0(a-unit) |
C35H70O3 | 538.928 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0023) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0009](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 107 |  |
Saturated-a-mycolic acid |
2-Dodecanoyl,3-hydroxy-docosanoic acid (or C23:0-C30:0, C32:0, C33:0) |
MMA0107 | Nagatoshi Fujiwara |
C20:0(b-unit)+C14:0(a-unit) |
C34H68O3 | 524.902 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0022](Ref. 0023) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0009](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 108 |  |
Saturated-a-mycolic acid |
2-Tridecanoyl,3-hydroxy-tetracosanoic acid (or C26:0, C28:0) |
MMA0108 | Nagatoshi Fujiwara |
C22:0(b-unit)+C15:0(a-unit) |
C37H74O3 | 566.982 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0023) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0009](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 109 |  |
Saturated-a-mycolic acid |
2-Tetradecanoyl,3-hydroxy-tetracosanoic acid (or C26:0, C28:0-C32:0) |
MMA0109 | Nagatoshi Fujiwara |
C22:0(b-unit)+C16:0(a-unit) |
C38H76O3 | 581.008 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0023](Ref. 0023) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0009](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 110 |  |
Saturated-a-mycolic acid |
2-Decanoyl,3-hydroxy-octacosanoic acid |
MMA0110 | Nagatoshi Fujiwara |
C26:0(b-unit)+C12:0(a-unit) |
C38H76O3 | 581.008 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0021) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0010/0011](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 111 |  |
Saturated-a-mycolic acid |
2-Dodecanoyl,3-hydroxy-hexacosanoic acid (or C28:0, C30:0, C32:0) |
MMA0111 | Nagatoshi Fujiwara |
C24:0(b-unit)+C14:0(a-unit) |
C38H76O3 | 581.008 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0021) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0010/0011](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 112 |  |
Saturated-a-mycolic acid |
2-Tetradecanoyl,3-hydroxy-tetracosanoic acid (or C26:0, C28:0, C30:0, C32:0, C34:0) |
MMA0112 | Nagatoshi Fujiwara |
C22:0(b-unit)+C16:0(a-unit) |
C38H76O3 | 581.008 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0021) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0010/0011](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 113 |  |
Monoenoic-a-mycolic acid |
2-Dodecanoyl,3-hydroxy-octacocenoic acid (or C30:1, C32:1, C34:1) |
MMA0113 | Nagatoshi Fujiwara |
C26:1(b-unit)+C14:0(a-unit) |
C40H78O3 | 607.046 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0024](Ref. 0021) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0010/0011](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 114 |  |
Monoenoic-a-mycolic acid |
2-Tetradecanoyl,3-hydroxy-hexacocenoic acid (or C28:1, C30:1, C32:1, C34:1, C36:1) |
MMA0114 | Nagatoshi Fujiwara |
C24:1(b-unit)+C16:0(a-unit) |
C40H78O3 | 607.046 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0024](Ref. 0021) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0010/0011](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 115 |  |
Dienoic-a-mycolic acid |
2-Dodecanoyl,3-hydroxy-C30:2 Acid (or C32:2, C34:2, C36:2) |
MMA0115 | Nagatoshi Fujiwara |
C28:2(b-unit)+C14:0(a-unit) |
C42H80O3 | 633.083 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0021) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0010/0011](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 116 |  |
Dienoic-a-mycolic acid |
2-Tetradecanoyl,3-hydroxy-C28:2 acid (or C30:2, C32:2, C34:2, C36:2, C38:2, C40:2) |
MMA0116 | Nagatoshi Fujiwara |
C26:2(b-unit)+C16:0(a-unit) |
C42H80O3 | 633.083 | |
Dosage of isoniazide effects the species of myclic acid (increase of diene and shorter carbon chain length).(Ref. 0019) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0034/0038/0048/0057) Induction of macrophage chemotactic factor(Ref. 0035/0036) Antitumor activity(Ref. 0038) Induction of TNF-a(Ref. 0038) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0021) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatograms 0010/0011](Ref. 0018) |
The mycolic acid composition of Nocardia asteroides(Ref. 0022) The higher the growth temperature is, the more saturated species of mycolic acid is increased.(Ref. 0020) Nocardia 15 strains can be separated of four groups by mycolic acid species. the first is mainly saturated C34-50 (ex. N. erythropolis). The second is monoenoic, dienoic C34-50 (N. rubra, N. corallina, N. lutea). The third is 1-4 double bond C44-58 (N. polychromogenes). The last is 1-5 double bond C56-68 (N. polychromogenes). Nocardia rubra has C38-52, mainly C44:0, C46:1, C48:2 with C12:0 or C14:0 as 2-alkyl chain.(Ref. 0021) Nocardia erythropolis has C32-46, mainly saturated mycolic acids. |
||||||||||||||
| 117 |  |
Bacterionemamycolic acid |
2-Alkyl,3-hydroxy,long-chain fatty acid |
MMA0117 | Nagatoshi Fujiwara |
Cm(b-unit)+Cn(a-unit) m=10, 12-19, n=8, 10, 13-18 |
|
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0025](Ref. 0025) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0012] |
Bacterionema matruchotii(Ref. 0025) |
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| 118 |  |
Dienoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-C50:2 acid |
MMA0118 | Nagatoshi Fujiwara |
C48:2(b-unit)+C22:0(a-unit) |
C70H136O3 | 1025.827 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0013] |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
||||||||||||||
| 119 |  |
Dienoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-C51:2 acid |
MMA0119 | Nagatoshi Fujiwara |
C49:2(b-unit)+C22:0(a-unit) |
C71H138O3 | 1039.854 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0013] |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
||||||||||||||
| 120 |  |
Dienoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-C52:2 acid |
MMA0120 | Nagatoshi Fujiwara |
C50:2(b-unit)+C22:0(a-unit) |
C72H140O3 | 1053.880 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0013] |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
||||||||||||||
| 121 |  |
Dienoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-C53:2 acid |
MMA0121 | Nagatoshi Fujiwara |
C51:2(b-unit)+C22:0(a-unit) |
C73H142O3 | 1067.907 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0013] |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
||||||||||||||
| 122 |  |
Dienoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-C54:2 acid |
MMA0122 | Nagatoshi Fujiwara |
C52:2(b-unit)+C22:0(a-unit) |
C74H144O3 | 1081.933 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0026](Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0013] |
Mycobacterium chelonae(Ref. 0001) Mycobacterium chitae(Ref. 0001) Mycobacterium fortuitum(Ref. 0001) Mycobacterium smegmatis(Ref. 0001) Mycobacterium diernhoferi(Ref. 0001/0004/0005) Mycobacterium parafortuitum(Ref. 0001/0004/0005) Mycobacterium rhodesiae(Ref. 0001/0004) Mycobacterium sp.strain 3707(Ref. 0001) |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
|||||||||||||
| 123 |  |
Dienoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-C55:2 acid |
MMA0123 | Nagatoshi Fujiwara |
C53:2(b-unit)+C22:0(a-unit) |
C75H146O3 | 1095.960 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0013] |
Mycobacterium chelonae(Ref. 0001) Mycobacterium chitae(Ref. 0001) Mycobacterium fortuitum(Ref. 0001) Mycobacterium smegmatis(Ref. 0001) Mycobacterium diernhoferi(Ref. 0004/0005) Mycobacterium parafortuitum(Ref. 0001/0004/0005) Mycobacterium rhodesiae(Ref. 0001/0004) Mycobacterium nonchromogenicum(Ref. 0001) |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
|||||||||||||
| 124 |  |
Dienoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-C57:2 acid |
MMA0124 | Nagatoshi Fujiwara |
C55:2(b-unit)+C22:0(a-unit) |
C77H150O3 | 1124.013 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0013] |
Mycobacterium chelonae(Ref. 0001) Mycobacterium chitae(Ref. 0001) Mycobacterium fortuitum(Ref. 0001) Mycobacterium smegmatis(Ref. 0001) Mycobacterium diernhoferi(Ref. 0004) Mycobacterium parafortuitum(Ref. 0001/0004/0005) Mycobacterium rhodesiae(Ref. 0001) Mycobacterium novum(Ref. 0001) Mycobacterium nonchromogenicum(Ref. 0001) |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
|||||||||||||
| 125 |  |
Dienoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-C56:2 acid |
MMA0125 | Nagatoshi Fujiwara |
C54:2(b-unit)+C22:0(a-unit) |
C76H148O3 | 1109.987 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0013] |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
||||||||||||||
| 126 |  |
Dienoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-C58:2 acid |
MMA0126 | Nagatoshi Fujiwara |
C56:2(b-unit)+C22:0(a-unit) |
C78H152O3 | 1138.040 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0013] |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
||||||||||||||
| 127 |  |
Dienoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy-C59:2 acid |
MMA0127 | Nagatoshi Fujiwara |
C57:2(b-unit)+C22:0(a-unit) |
C79H154O3 | 1152.066 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
Mycobacterium nonchromogenicum(Ref. 0001) |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
|||||||||||||
| 128 |  |
Dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy-C46:2 acid |
MMA0128 | Nagatoshi Fujiwara |
C44:2(b-unit)+C24:0(a-unit) |
C68H132O3 | 997.774 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
Mycobacterium sp.strain 3707(Ref. 0005) |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
|||||||||||||
| 129 |  |
Dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy-C47:2 acid |
MMA0129 | Nagatoshi Fujiwara |
C45:2(b-unit)+C24:0(a-unit) |
C69H134O3 | 1011.800 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
Mycobacterium sp.strain 3707(Ref. 0005) |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
|||||||||||||
| 130 |  |
Dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy-C48:2 acid |
MMA0130 | Nagatoshi Fujiwara |
C46:2(b-unit)+C24:0(a-unit) |
C70H136O3 | 1025.827 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
Mycobacterium sp.strain 3707(Ref. 0005) |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
|||||||||||||
| 131 |  |
Dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy-C49:2 acid |
MMA0131 | Nagatoshi Fujiwara |
C47:2(b-unit)+C24:0(a-unit) |
C71H138O3 | 1039.854 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
Mycobacterium sp.strain 3707(Ref. 0005) |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
|||||||||||||
| 132 |  |
Dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy-C50:2 acid |
MMA0132 | Nagatoshi Fujiwara |
C48:2(b-unit)+C24:0(a-unit) |
C72H140O3 | 1053.880 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0027](Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
||||||||||||||
| 133 |  |
Dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy-C51:2 acid |
MMA0133 | Nagatoshi Fujiwara |
C49:2(b-unit)+C24:0(a-unit) |
C73H142O3 | 1067.907 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
||||||||||||||
| 134 |  |
Dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy-C52:2 acid |
MMA0134 | Nagatoshi Fujiwara |
C50:2(b-unit)+C24:0(a-unit) |
C74H144O3 | 1081.933 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0028](Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
Mycobacterium chelonae(Ref. 0001/0004/0005) Mycobacterium chitae(Ref. 0004/0005) Mycobacterium fortuitum(Ref. 0001/0004/0005) Mycobacterium smegmatis(Ref. 0001/0005) Mycobacterium diernhoferi(Ref. 0001) Mycobacterium rhodesiae(Ref. 0001/0004) Mycobacterium nonchromogenicum(Ref. 0005) Mycobacterium sp.strain 3707(Ref. 0001/0005) Mycobacterium szulgai(Ref. 0005) |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
|||||||||||||
| 135 |  |
Dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy-C53:2 acid |
MMA0135 | Nagatoshi Fujiwara |
C51:2(b-unit)+C24:0(a-unit) |
C75H146O3 | 1095.960 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0029](Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
Mycobacterium chelonae(Ref. 0001/0005) Mycobacterium chitae(Ref. 0001/0004/0005) Mycobacterium fortuitum(Ref. 0001/0005) Mycobacterium smegmatis(Ref. 0001/0004/0005) Mycobacterium rhodesiae(Ref. 0001/0004) Mycobacterium nonchromogenicum(Ref. 0001/0005) Mycobacterium terrae(Ref. 0005) Mycobacterium sp.strain 3707(Ref. 0005) Mycobacterium szulgai(Ref. 0005) Mycobacterium novum(Ref. 0005) |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
|||||||||||||
| 136 |  |
Dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy-C54:2 acid |
MMA0136 | Nagatoshi Fujiwara |
C52:2(b-unit)+C24:0(a-unit) |
C76H148O3 | 1109.987 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectra 0030/0031](Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
Mycobacterium chelonae(Ref. 0001/0004/0005) Mycobacterium chitae(Ref. 0001/0004/0005) Mycobacterium peregrinum PE-1(Ref. 0004) Mycobacterium fortuitum(Ref. 0001/0004/0005) Mycobacterium smegmatis(Ref. 0001/0005) Mycobacterium rhodesiae(Ref. 0001/0004) Mycobacterium terrae(Ref. 0005) Mycobacterium novum(Ref. 0005) Mycobacterium sp.strain 3707(Ref. 0005) Mycobacterium scrofulaceum(Ref. 0005) Mycobacterium szulgai(Ref. 0005) Mycobacterium diernhoferi(Ref. 0001) |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
|||||||||||||
| 137 |  |
Dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy-C55:2 acid |
MMA0137 | Nagatoshi Fujiwara |
C53:2(b-unit)+C24:0(a-unit) |
C77H150O3 | 1124.013 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectra 0031/0032](Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
Mycobacterium chelonae(Ref. 0001/0004/0005) Mycobacterium chitae(Ref. 0001/0004/0005) Mycobacterium porcinum(Ref. 0004) Mycobacterium fortuitum(Ref. 0001/0005) Mycobacterium smegmatis(Ref. 0001/0004/0005) Mycobacterium parafortuitum(Ref. 0001) Mycobacterium hodesiae(Ref. 0001) Mycobacterium nonchromogenicum(Ref. 0001/0004/0005) Mycobacterium terrae(Ref. 0005) Mycobacterium novum(Ref. 0001/0005) Mycobacterium scrofulaceum(Ref. 0005) Mycobacterium szulgai(Ref. 0005) |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
|||||||||||||
| 138 |  |
Dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy-C56:2 acid |
MMA0138 | Nagatoshi Fujiwara |
C54:2(b-unit)+C24:0(a-unit) |
C78H152O3 | 1138.040 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectra 0033/0034](Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
Mycobacterium chelonae(Ref. 0001/0004/0005) Mycobacterium chitae(Ref. 0001/0004/0005) Mycobacterium fortuitum(Ref. 0001/0004/0005) Mycobacterium smegmatis(Ref. 0001/0005) Mycobacterium parafortuitum(Ref. 0001/0005) Mycobacterium rhodesiae(Ref. 0001/0004) Mycobacterium nonchromogenicum(Ref. 0005) Mycobacterium terrae(Ref. 0005) Mycobacterium novum(Ref. 0005) Mycobacterium scrofulaceum(Ref. 0005) Mycobacterium szulgai(Ref. 0005) |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
|||||||||||||
| 139 |  |
Dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy-C57:2 acid |
MMA0139 | Nagatoshi Fujiwara |
C55:2(b-unit)+C24:0(a-unit) |
C79H154O3 | 1152.066 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectra 0034/0035](Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
Mycobacterium chelonae(Ref. 0001) Mycobacterium chitae(Ref. 0001/0004/0005) Mycobacterium fortuitum(Ref. 0001/0005) Mycobacterium smegmatis(Ref. 0001/0005) Mycobacterium nonchromogenicum(Ref. 0001/0005) Mycobacterium terrae(Ref. 0004/0005) Mycobacterium novum(Ref. 0001/0004/0005) Mycobacterium triviale(Ref. 0004) Mycobacterium scrofulaceum(Ref. 0005) Mycobacterium szulgai(Ref. 0005) |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
|||||||||||||
| 140 |  |
Dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy-C58:2 acid |
MMA0140 | Nagatoshi Fujiwara |
C56:2(b-unit)+C24:0(a-unit) |
C80H156O3 | 1166.093 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
Mycobacterium chelonae(Ref. 0001) Mycobacterium chirae(Ref. 0005) Mycobacterium fortuitum(Ref. 0001/0004) Mycobacterium smegmatis(Ref. 0001/0004) Mycobacterium nonchromogenicum(Ref. 0001/0005) Mycobacterium terrae(Ref. 0005) Mycobacterium novum(Ref. 0005) Mycobacterium scrofulaceum(Ref. 0005) Mycobacterium szulgai(Ref. 0005) |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
|||||||||||||
| 141 |  |
Dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy-C59:2 acid |
MMA0141 | Nagatoshi Fujiwara |
C57:2(b-unit)+C24:0(a-unit) |
C81H158O3 | 1180.119 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
||||||||||||||
| 142 |  |
Dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy-C60:2 acid |
MMA0142 | Nagatoshi Fujiwara |
C58:2(b-unit)+C24:0(a-unit) |
C82H160O3 | 1194.146 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0036](Ref. 0001/0005/0010) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
||||||||||||||
| 143 |  |
Dienoic-a'-mycolic acid |
2-Eicosanoyl,3-hydroxy-C46:2 acid |
MMA0143 | Nagatoshi Fujiwara |
C44:2(b-unit)+C22:0(a-unit) |
C66H128O3 | 969.721 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
Mycobacterium fortuitum(Ref. 0001) |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
|||||||||||||
| 144 |  |
Dienoic-a'-mycolic acid |
2-Docosanoyl,3-hydroxy-C42:2 acid |
MMA0144 | Nagatoshi Fujiwara |
C40:2(b-unit)+C24:0(a-unit) |
C64H124O3 | 941.668 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
||||||||||||||
| 145 |  |
Dienoic-a'-mycolic acid |
2-Docosanoyl,3-hydroxy-C44:2 acid |
MMA0145 | Nagatoshi Fujiwara |
C42:2(b-unit)+C24:0(a-unit) |
C66H128O3 | 969.721 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
||||||||||||||
| 146 |  |
Dienoic-a'-mycolic acid |
2-Docosanoyl,3-hydroxy-C48:2 acid |
MMA0146 | Nagatoshi Fujiwara |
C46:2(b-unit)+C24:0(a-unit) |
C70H136O3 | 1025.827 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
||||||||||||||
| 147 |  |
Dienoic-a'-mycolic acid |
2-Docosanoyl,3-hydroxy-C46:2 acid |
MMA0147 | Nagatoshi Fujiwara |
C44:2(b-unit)+C24:0(a-unit) |
C68H132O3 | 997.774 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0037](Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
In Mycobacterium smegmatis, l=15,17,19, m=11,13, n=16,18,20, x=21(Ref. 0007), C75-79,a-unit, C24:0(Ref. 0003)The composition effected by growth temperature.(Ref. 0010) In Mycobacterium phlei, C72, 74, 76-80 (or dicyclopropanring) (Ref. 0010/0014) In Mycobacterium bovis, C74-88, a-unit C22:0 or C24:0(Ref. 0015) |
||||||||||||||
| 148 |  |
Monomethyl,dienoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy,monomethyl-C51:2 acid |
MMA0148 | Nagatoshi Fujiwara |
CH3-C49:2(b-unit)+C22:0(a-unit) |
C72H140O3 | 1053.880 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
|||||||||||||||
| 149 |  |
Monomethyl,dienoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy,monomethyl-C52:2 acid |
MMA0149 | Nagatoshi Fujiwara |
CH3-C50:2(b-unit)+C22:0(a-unit) |
C73H142O3 | 1067.907 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
|||||||||||||||
| 150 |  |
Monomethyl,dienoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy,monomethyl-C53:2 acid |
MMA0150 | Nagatoshi Fujiwara |
CH3-C51:2(b-unit)+C22:0(a-unit) |
C74H144O3 | 1081.933 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
|||||||||||||||
| 151 |  |
Monomethyl,dienoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy,monomethyl-C54:2 acid |
MMA0151 | Nagatoshi Fujiwara |
CH3-C52:2(b-unit)+C22:0(a-unit) |
C75H146O3 | 1095.960 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
|||||||||||||||
| 152 |  |
Monomethyl,dienoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy,monomethyl-C55:2 acid |
MMA0152 | Nagatoshi Fujiwara |
CH3-C53:2(b-unit)+C22:0(a-unit) |
C76H148O3 | 1109.987 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
|||||||||||||||
| 153 |  |
Monomethyl,dienoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy,monomethyl-C56:2 acid |
MMA0153 | Nagatoshi Fujiwara |
CH3-C54:2(b-unit)+C22:0(a-unit) |
C77H150O3 | 1124.013 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
|||||||||||||||
| 154 |  |
Monomethyl,dienoic-a-mycolic acid |
2-Eicosanoyl,3-hydroxy,monomethyl-C57:2 acid |
MMA0154 | Nagatoshi Fujiwara |
CH3-C55:2(b-unit)+C22:0(a-unit) |
C78H152O3 | 1138.040 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0001] |
|||||||||||||||
| 155 |  |
Monomethyl,dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy,monomethyl-C49:2 acid |
MMA0155 | Nagatoshi Fujiwara |
CH3-C47:2(b-unit)+C24:0(a-unit) |
C72H140O3 | 1053.880 | |
CCD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0013] |
|||||||||||||||
| 156 |  |
Monomethyl,dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy,monomethyl-C50:2 acid |
MMA0156 | Nagatoshi Fujiwara |
CH3-C48:2(b-unit)+C24:0(a-unit) |
C73H142O3 | 1067.907 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0013] |
|||||||||||||||
| 157 |  |
Monomethyl,dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy,monomethyl-C51:2 acid |
MMA0157 | Nagatoshi Fujiwara |
CH3-C49:2(b-unit)+C24:0(a-unit) |
C74H144O3 | 1081.933 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0013] |
|||||||||||||||
| 158 |  |
Monomethyl,dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy,monomethyl-C52:2 acid |
MMA0158 | Nagatoshi Fujiwara |
CH3-C50:2(b-unit)+C24:0(a-unit) |
C75H146O3 | 1095.960 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0013] |
|||||||||||||||
| 159 |  |
Monomethyl,dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy,monomethyl-C53:2 acid |
MMA0159 | Nagatoshi Fujiwara |
CH3-C51:2(b-unit)+C24:0(a-unit) |
C76H148O3 | 1109.987 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0013] |
|||||||||||||||
| 160 |  |
Monomethyl,dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy,monomethyl-C54:2 acid |
MMA0160 | Nagatoshi Fujiwara |
CH3-C52:2(b-unit)+C24:0(a-unit) |
C77H150O3 | 1124.013 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) [Spectrum 0038](Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0013] |
|||||||||||||||
| 161 |  |
Monomethyl,dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy,monomethyl-C55:2 acid |
MMA0161 | Nagatoshi Fujiwara |
CH3-C53:2(b-unit)+C24:0(a-unit) |
C78H152O3 | 1138.040 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0013] |
|||||||||||||||
| 162 |  |
Monomethyl,dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy,monomethyl-C56:2 acid |
MMA0162 | Nagatoshi Fujiwara |
CH3-C54:2(b-unit)+C24:0(a-unit) |
C78H154O3 | 1140.056 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0013] |
|||||||||||||||
| 163 |  |
Monomethyl,dienoic-a-mycolic acid |
2-Docosanoyl,3-hydroxy,monomethyl-C58:2 acid |
MMA0163 | Nagatoshi Fujiwara |
CH3-C56:2(b-unit)+C24:0(a-unit) |
C81H158O3 | 1180.119 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0013] |
|||||||||||||||
| 164 |  |
Monoenoic-a'-mycolic acid |
2-Docosanoyl,3-hydroxy-C38:1 acid |
MMA0164 | Nagatoshi Fujiwara |
C36:1(b-unit)+C24:0(a-unit) |
C60H118O3 | 887.577 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0013] |
As a'-mycolic acid in Mycobacterium smegmatis, x=21, l=17,19, m=15,17,19,21(Ref. 0012)x=21, C60,62,64,66,68,74-83(Ref. 0013)x=21, C60-66(Ref. 0003)effect of growth temperature(Ref. 0002) As a'-mycolic acid in Mycobacterium phlei, effect of growth temperature(Ref. 0010) As a'-mycolic acid in Mycobacterium chelonei, x=21, l=15,17, m=17,19 C60-64(Ref. 0009) |
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| 165 |  |
Monoenoic-a'-mycolic acid |
2-Docosanoyl,3-hydroxy-C34:1 acid |
MMA0165 | Nagatoshi Fujiwara |
C32:1(b-unit)+C24:0(a-unit) |
C56H110H3 | 786.496 | |
CD1b-restricted antigen(Ref. 0029) Inhibition of the biosynthesis of mycolic acid by isoniazid(Ref. 0059/0060) (As mycoloyl glycolipid) Granuloma forming activity(Ref. 0031/0032) Toxicity(Ref. 0030/0033) Immunomodifying activities(Ref. 0030) Antitumor activity(Ref. 0037/0039) Adjuvanticity(Ref. 0041/0042) Tumor-necrosis-factor-priming activity(Ref. 0043) In vivo induction of apoptosis in the thymus(Ref. 0040) Activation of protein kinase C(Ref. 0043) Antigenic properties(Ref. 0052/0053/0054) Production of anti-cord factor antibody(Ref. 0045) Increase of anti-cord factor IgG antibody in tuberculous patient(Ref. 0046/0047/0051/0055) |
Chloroform,n-Hexane |
[M]+(molecular Ion),[M-15]+(loss of -CH3),[M-90]+(loss of trimethylsilanol),[A]+(TMS-alkoxy ion resulting from C2-C3 cleavage),[A-90]+(loss of trimethylsilanol from [A]+),[B]+(TMS-oxymethylene carboxylic acid ester resulting from C3-C4 cleavage),[B-29]+(loss of CHO from [B]+), (after methylation and trimethylsilylation) (Ref. 0001/0004/0005) |
Thin-layer chromatogram of mycolic acid methyl esters,Chromatogram was developed with a solvent of n-hexane-diethyl ether(4:1, v/v) and visualized with charring after being sprayed with 50% H2SO4 [Chromatogram 0013] |
Mycobacterium chitae(Ref. 0001) |
As a'-mycolic acid in Mycobacterium smegmatis, x=21, l=17,19, m=15,17,19,21(Ref. 0012)x=21, C60,62,64,66,68,74-83(Ref. 0013)x=21, C60-66(Ref. 0003)effect of growth temperature(Ref. 0002) As a'-mycolic acid in Mycobacterium phlei, effect of growth temperature(Ref. 0010) As a'-mycolic acid in Mycobacterium chelonei, x=21, l=15,17, m=17,19 C60-64(Ref. 0009) |
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| 166 |  |
Monoenoic-a'-mycolic acid |
2-Docosanoyl,3-hydroxy-C36:1 acid |
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