Category:LBS/Biosynthesis/CeramideDeg - Revision history

Yoshimoto at 06:32, 18 December 2017

2017-12-18T06:32:17Z

← Older revision		Revision as of 15:32, 18 December 2017
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	\|-		\|-
	\| Acid ceramidase		\| Acid ceramidase
	\| ASAH1		\| [http://www.uniprot.org/uniprot/Q13510 ASAH1]
	\|		\| 8p22
	\| Localized in lysosome. Its deficiency causes lysosomal accumulation of ceramides (Farber disease).<ref>Ferlinz K, Kopal G, Bernardo K et al. (2001) "Human acid ceramidase: processing, glycosylation, and lysosomal targeting" J Biol Chem 276(38):35352-35360.</ref>		\| Localized in lysosome. Its deficiency causes lysosomal accumulation of ceramides (Farber disease).<ref>Ferlinz K, Kopal G, Bernardo K et al. (2001) "Human acid ceramidase: processing, glycosylation, and lysosomal targeting" J Biol Chem 276(38):35352-35360.</ref>
	\|-		\|-
	\| Neutral ceramidase		\| Neutral ceramidase
	\| ASAH2		\| [http://www.uniprot.org/uniprot/Q9NR71 ASAH2]
	\|		\| 10q11.23
	\| Localized to the plasma membrane and expressed in the small intestine and colon. <ref>Coant N, Sakamoto W, Mao C, Hannun YA (2015) "Ceramidases, roles in sphingolipid metabolism and in health and disease" Adv Biol Regul 63:122-131</ref>		\| Localized to the plasma membrane and expressed in the small intestine and colon. <ref>Coant N, Sakamoto W, Mao C, Hannun YA (2015) "Ceramidases, roles in sphingolipid metabolism and in health and disease" Adv Biol Regul 63:122-131</ref>
	\|-		\|-
	\|rowspan="3"\| Alkaline ceramidase		\|rowspan="3"\| Alkaline ceramidase
	\| ACER1		\| [http://www.uniprot.org/uniprot/Q8TDN7 ACER1](ASAH3)
	\|		\| 19p13.3
	\| Localized to the endoplasmic reticulum (ER) and highly expressed in skin.		\| Localized to the endoplasmic reticulum (ER) and highly expressed in skin.
	\|-		\|-
	\| ACER2		\| [http://www.uniprot.org/uniprot/Q5QJU3 ACER2](ASAH3L)
	\|		\| 9p22.1
	\| Localized to the Golgi complex and highly expressed in placenta.		\| Localized to the Golgi complex and highly expressed in placenta.
	\|-		\|-
	\| ACER3		\| [http://www.uniprot.org/uniprot/Q9NUN7 ACER3](APHC)
	\|		\| 11q13.5
	\| Localized to the ER and the Golgi complex, and ubiquitously expressed.		\| Localized to the ER and the Golgi complex, and ubiquitously expressed.
	\|-		\|-
	\| rowspan="2"\| S1P phosphatase		\| rowspan="2"\| S1P phosphatase
	\| SGPP1		\| [http://www.uniprot.org/uniprot/Q9BX95 SGPP1]
	\|		\| 14q23.2
	\| Specifically dephosphorylates sphingosine 1-phosphate (S1P), dihydro-S1P, and phyto-S1P.		\| Specifically dephosphorylates sphingosine 1-phosphate (S1P), dihydro-S1P, and phyto-S1P.
	\|-		\|-
	\| SGPP2		\| [http://www.uniprot.org/uniprot/Q8IWX5 SGPP2]
	\|		\| 2q36.1
	\| Localized to the ER and dephosphorylates S1P and dihydro-S1P.<ref>Ogawa C, Kihara A, Gokoh M, Igarashi Y (2003) "Identification and characterization of a novel human sphingosine-1-phosphate phosphohydrolase, hSPP2" J Biol Chem 278(2):1268-1272.</ref>		\| Localized to the ER and dephosphorylates S1P and dihydro-S1P.<ref>Ogawa C, Kihara A, Gokoh M, Igarashi Y (2003) "Identification and characterization of a novel human sphingosine-1-phosphate phosphohydrolase, hSPP2" J Biol Chem 278(2):1268-1272.</ref>
	\|-		\|-
	\| S1P lyase		\| S1P lyase
	\| SGPL1		\| [http://www.uniprot.org/uniprot/O95470 SGPL1]
	\|		\| 10q22.1
	\|		\|
	\|-		\|-
	\|colspan="4"\|<references/>		\|colspan="4"\|<references/>
	\|}		\|}

Editor at 00:12, 18 December 2017

2017-12-18T00:12:14Z

← Older revision		Revision as of 09:12, 18 December 2017
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	\|style="background:AntiqueWhite;border-radius: 0px 20px 0px 0px" \| palmitate		\|style="background:AntiqueWhite;border-radius: 0px 20px 0px 0px" \| palmitate
	\|-		\|-
	\|colspan="11" style="background:AntiqueWhite;border-radius: 0px 0px 20px 20px; font-weight: 600; text-shadow:black 3px 3px 5px; color: black;"\| <big>~~Cytosol~~</big>		\|colspan="11" style="background:AntiqueWhite;border-radius: 0px 0px 20px 20px; font-weight: 600; text-shadow:black 3px 3px 5px; color: black;"\| <big>ER, Golgi and Lysosomes</big>
	\|}		\|}

Editor at 00:11, 18 December 2017

2017-12-18T00:11:00Z

@@ Line 14: / Line 14: @@
 |-
 |colspan="11" style="background:AntiqueWhite;border-radius: 0px 0px 20px 20px; font-weight: 600; text-shadow:black 3px 3px 5px; color: black;"| <big>Cytosol</big>
 |}

Editor at 04:05, 28 January 2017

2017-01-28T04:05:29Z

← Older revision		Revision as of 13:05, 28 January 2017
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	{\| style="text-align:center;border-spacing:0;border-collapse:collapse;"		{\| style="text-align:center;border-spacing:0;border-collapse:collapse;"
	\|-		\|-
	\|style="background:AntiqueWhite;border-radius: 20px 0px 0px 0px" \| ~~<br/>~~ceramide		\|style="background:AntiqueWhite;border-radius: 20px 0px 0px 0px" \| ceramide
	\|style="background:AntiqueWhite" \|  <small>ceramidase</small><br/>[[File:~~Arrow00r~~.png]]<br/>		\|style="background:AntiqueWhite" \|  <small>ceramidase</small><br/>[[File:Arrow2rr.png]]<br/><small>   fatty acid</small>
	\|style="background:AntiqueWhite" \| ~~<br/>~~sphingosine		\|style="background:AntiqueWhite" \| sphingosine
	\|style="background:AntiqueWhite" \| ~~ ~~<small>S1P phosphatase</small> <br/>[[File:~~Arrow00r~~.png]]<br/>		\|style="background:AntiqueWhite" \| <small>S1P phosphatase</small><br/>[[File:Arrow00h.png]]<br/>  <small></small>
	\|style="background:AntiqueWhite" \| ~~<br/>~~ sphingosine<br/> 1-phosphate		\|style="background:AntiqueWhite" \| sphingosine<br/> 1-phosphate
	\|style="background:AntiqueWhite" \| ~~<br/>~~<small>S1P lyase</small><br/>[[File:~~Arrow2rr35~~.png]]<br/>  <small>~~fatty acid~~</small>		\|style="background:AntiqueWhite" \| <small>S1P lyase</small><br/>[[File:Arrow2rr.png]]<br/>  <small>phosphoethanolamine</small>
	\|style="background:AntiqueWhite" \| ~~<br/>~~hexadecenal		\|style="background:AntiqueWhite" \| hexadecenal
	\|style="background:AntiqueWhite" \|  <br/>[[File:~~Arrow00r~~.png]]<br/>  <small></small>		\|style="background:AntiqueWhite" \|  <br/>[[File:Arrow00r35.png]]<br/>  <small></small>
	\|style="background:AntiqueWhite" \| ~~<br/>~~hexadecanal		\|style="background:AntiqueWhite" \| hexadecanal
	\|style="background:AntiqueWhite" \|  <br/>[[File:~~Arrow00r~~.png]]<br/>  <small></small>		\|style="background:AntiqueWhite" \|  <br/>[[File:Arrow00r35.png]]<br/>  <small></small>
	\|style="background:AntiqueWhite;border-radius: 0px 20px 0px 0px" \| ~~<br/>~~ palmitate		\|style="background:AntiqueWhite;border-radius: 0px 20px 0px 0px" \| palmitate
	\|-		\|-
	\|colspan="11" style="background:AntiqueWhite;border-radius: 0px 0px 20px 20px; font-weight: 600; text-shadow:black 3px 3px 5px; color: black;"\| <big>Cytosol</big>		\|colspan="11" style="background:AntiqueWhite;border-radius: 0px 0px 20px 20px; font-weight: 600; text-shadow:black 3px 3px 5px; color: black;"\| <big>Cytosol</big>
	\|}		\|}

Editor: Created page with "{| style="text-align:center;border-spacing:0;border-collapse:collapse;" |- |style="background:AntiqueWhite;border-radius: 20px 0px 0px 0px" |
ceramide |style="background:..."

2017-01-28T03:54:15Z

Created page with "{| style="text-align:center;border-spacing:0;border-collapse:collapse;" |- |style="background:AntiqueWhite;border-radius: 20px 0px 0px 0px" | ceramide |style="background:..."

New page

{| style="text-align:center;border-spacing:0;border-collapse:collapse;"
|-
|style="background:AntiqueWhite;border-radius: 20px 0px 0px 0px" | ceramide
|style="background:AntiqueWhite" |  ceramidase [[File:Arrow00r.png]] 
|style="background:AntiqueWhite" | sphingosine
|style="background:AntiqueWhite" |  S1P phosphatase [[File:Arrow00r.png]] 
|style="background:AntiqueWhite" | sphingosine 1-phosphate
|style="background:AntiqueWhite" | S1P lyase [[File:Arrow2rr35.png]]   fatty acid
|style="background:AntiqueWhite" | hexadecenal
|style="background:AntiqueWhite" |   [[File:Arrow00r.png]]   
|style="background:AntiqueWhite" | hexadecanal
|style="background:AntiqueWhite" |   [[File:Arrow00r.png]]   
|style="background:AntiqueWhite;border-radius: 0px 20px 0px 0px" | palmitate
|-
|colspan="11" style="background:AntiqueWhite;border-radius: 0px 0px 20px 20px; font-weight: 600; text-shadow:black 3px 3px 5px; color: black;"| <big>Cytosol</big>
|}

Category:LBS/Biosynthesis/CeramideDeg - Revision history

Yoshimoto at 06:32, 18 December 2017

Editor at 00:12, 18 December 2017

Editor at 00:11, 18 December 2017

Editor at 04:05, 28 January 2017

Editor: Created page with "{| style="text-align:center;border-spacing:0;border-collapse:collapse;" |- |style="background:AntiqueWhite;border-radius: 20px 0px 0px 0px" | ceramide |style="background:..."

Editor: Created page with "{| style="text-align:center;border-spacing:0;border-collapse:collapse;" |- |style="background:AntiqueWhite;border-radius: 20px 0px 0px 0px" |
ceramide |style="background:..."