Category:LBSP - Revision history

Yasugi at 05:59, 15 August 2022

2022-08-15T05:59:22Z

← Older revision		Revision as of 14:59, 15 August 2022
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	<references/>		<references/>

			==Sphingolipids in All Kingdoms==

			{{:Category:ScientificClassification/LBSC}}

Yasugi: Undo revision 116964 by Yasugi (talk)

2022-08-11T02:17:59Z

Undo revision 116964 by Yasugi (talk)

← Older revision		Revision as of 11:17, 11 August 2022
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	:Phosphatidylinositol + Ceramide → Inositol phosphoceramide + Diacylglycerol		:Phosphatidylinositol + Ceramide → Inositol phosphoceramide + Diacylglycerol

	~~==Phosphosphingolipids in All Kingdoms==~~

	~~{{:Category:ScientificClassification/LBSC}}~~

	<references/>		<references/>

Yasugi at 02:07, 11 August 2022

2022-08-11T02:07:19Z

← Older revision		Revision as of 11:07, 11 August 2022
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	:Phosphatidylinositol + Ceramide → Inositol phosphoceramide + Diacylglycerol		:Phosphatidylinositol + Ceramide → Inositol phosphoceramide + Diacylglycerol

			==Phosphosphingolipids in All Kingdoms==

			{{:Category:ScientificClassification/LBSC}}

	<references/>		<references/>

Editor: /* {{bilingual|グリコシルイノシトールホスホセラミド|GIPC}} */

2017-09-13T05:55:46Z

@@ Line 116: / Line 116: @@
 # (P1 series is sphingomyelin and ceramide phosphoethanolamine.)
+|
-グリコシルイノシトールホスホセラミド (GIPC) は植物に多く含まれるため、歴史的にフィト糖脂質 (phytoglycolipid, PGL) と呼ばれました。その後、菌類や植物だけでなく、バクテリア、原生生物、動物界（脊索動物は除く）での存在がわかり、現在はGIPCと呼ばれます。
+グリコシルイノシトールホスホセラミド (GIPC) は植物に多く含まれるため、以前はフィト糖脂質 (phytoglycolipid, PGL) と呼ばれました。その後、菌類や植物だけでなく、バクテリア、原生生物、動物界（脊索動物は除く）に存在することがわかり、現在はGIPCと呼ばれます。
-構造はセラミドにイノシトールリン酸が結合したイノシトールホスホセラミド（IPC)に、様々な糖がついて伸長します。
+セラミドにイノシトールリン酸が結合したイノシトールホスホセラミド（IPC)に、様々な糖がついて伸長します。
 LipidBankではGIPCを4つに分類しています。
@@ Line 128: / Line 126: @@
 # その他
 }}
 ===Biosynthesis===

Editor: /* {{Bilingual|スフィンゴミエリン|Sphingomyelin}} */

2017-09-13T05:49:58Z

← Older revision		Revision as of 14:49, 13 September 2017
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	</tr>		</tr>
	<tr>		<tr>
	<td style="transform:translateY(-0.3em);">(C<sub>14</sub>-chain)</td><td style="transform: rotate(45deg) scaleX(2)">＝</td><td style="transform:scaleX(1.5)">／</td><td style="transform:scaleX(1.5)">＼</td><td style="transform:scaleX(1.5)">／</td><td style="transform:rotate(30deg) translateY(-0.1em) translateX(-0.3em)">ー </td><td>Oー</td><td>Pー</td><td style="color: red;">OCH<sub>2</sub>CH<sub>2</sub>N<sup>+</sup>(CH<sub>3</sub>)<sub>3</sub></td>		<td style="transform:translateY(-0.3em);">(C<sub>14</sub>-chain)</td><td style="transform: rotate(45deg) scaleX(2)">＝</td><td style="transform:scaleX(1.5)">／</td><td style="transform:scaleX(1.5)">＼</td><td style="transform:scaleX(1.5)">／</td><td style="transform:rotate(30deg) translateY(-0.1em) translateX(-0.3em)">ー </td><td>Oー</td><td>Pー</td><td style="color: red;">OCH<sub>2</sub>CH<sub>2</sub><b>N<sup>+</sup>(CH<sub>3</sub>)<sub>3</sub></b></td>
	</tr>		</tr>
	<tr><td colspan="3" style="text-align:right; transform:translateX(0.5em);">(fatty acid) ー</td>		<tr><td colspan="3" style="text-align:right; transform:translateX(0.5em);">(fatty acid) ー</td>

Editor: /* {{Bilingual|セラミドホスホエタノールアミン|CPE and CAEP}} */

2017-09-13T05:49:30Z

@@ Line 66: / Line 66: @@
 セラミドアミノエチルホスホン酸(CAEP)はCPEと似た構造ですがC-P結合を持ち、原生生物、刺胞動物、軟体動物、棘皮動物などに存在します。
 }}
 ===Biosynthesis===

Editor: /* {{Bilingual|スフィンゴミエリン|Sphingomyelin}} */

2017-09-13T05:47:56Z

@@ Line 12: / Line 12: @@
 スフィンゴミエリン (SM) はセラミドにホスホコリンが結合した構造で、脊椎動物の神経系、特にミエリン鞘に多くあります。SMの長鎖塩基はスフィンゴ糖脂質と同様に d18:1 が多く、 d18:0 も含まれます。脂肪酸は鎖長 16-24 で構成され、ヒドロキシ酸は通常含まれません。
 }}
@@ Line 23: / Line 43: @@
 ;Mammalian SM synthase family (SMS1 in golgi; SMS2 in plasma membrane)
 : Phosphatidylcholine + Ceramide &rarr; Sphingomyelin + 1,2-Diacylglycerol
+:
 ;SM degradation (Sphingomyelinase) SMase
 : Sphingomyelin &rarr; Ceramide + Phosphocholine

Editor at 23:44, 21 August 2017

2017-08-21T23:44:29Z

← Older revision		Revision as of 08:44, 22 August 2017
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	{{LB/Header}}		{{LB/Header}}
	{{Hierarchy\|{{PAGENAME}}}}		{{Hierarchy\|{{PAGENAME}}}}
	~~{\| style="float:right"~~		__TOC__
	\| __TOC__
	\|}


	==Sphingomyelin ~~スフィンゴミエリン~~==
			=={{Bilingual\|スフィンゴミエリン\|Sphingomyelin}}==

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	<references/>		<references/>

	==~~Ceramide phosphoethanolamine (~~CPE) and ~~ceramide aminoethylphosphonate (~~CAEP~~)<br>セラミドホスホエタノールアミンとセラミドアミノエチルホスホン酸~~==		=={{Bilingual\|セラミドホスホエタノールアミン\|CPE and CAEP}}==

	{{Twocolumn\|		{{Twocolumn\|
	Ceramide phosphoethanolamine (CPE) is formed from a ceramide phosphate linked with ethanolamine. It is often found in insects, trace amount in many animals including bacteria, protozoa, and mammals, and absent in plants or fungi.<ref>Bhat HB, Ishitsuka R, Inaba T, Murate M, Abe M, Makino A, Kohyama-Koganeya A, Kurahashi A, Kishimoto T, Tahara M, Yamamo A, Nagamune K, Hirabayashi Y, Juni N, Umeda M, Fujimori F, Nishibori K, Yamaji A, Greimel P, Kobayashi T, Evaluation of aegerolysins as novel tools to detect and visualize ceramide phosphoethanolamine, a major sphingolipid in invertebrates, FASEB J. 2015 29:3920-34.PMID 26060215 Hannich JT, Umebayashi K, Riezman H. Distribution and functions of sterols and sphingolipids. Cold Spring Harb Perspect Biol. 2011 3. pii: a004762.PMID 21454248</ref> Ceramide aminoethylphosphonate (CAEP) is similar to CPE but is formed by the C-P bonding. It is found in protozoa, cnidaria, mollusca, and echinodermata.<ref>Hori T, Itasaka O, Inoue H. Biochemistry of shellfish lipid. 3. Purification and elemental analysis of ceramide aminoethylphosphonate from Corbicula complex lipid mixtures. J Biochem. 1966 59:570-3. PMID 5962677</ref>		Ceramide phosphoethanolamine (CPE) is formed from a ceramide phosphate linked with ethanolamine. It is often found in insects, trace amount in many animals including bacteria, protozoa, and mammals, and absent in plants or fungi.<ref>Bhat HB, Ishitsuka R, Inaba T, Murate M, Abe M, Makino A, Kohyama-Koganeya A, Kurahashi A, Kishimoto T, Tahara M, Yamamo A, Nagamune K, Hirabayashi Y, Juni N, Umeda M, Fujimori F, Nishibori K, Yamaji A, Greimel P, Kobayashi T, Evaluation of aegerolysins as novel tools to detect and visualize ceramide phosphoethanolamine, a major sphingolipid in invertebrates, FASEB J. 2015 29:3920-34.PMID 26060215 Hannich JT, Umebayashi K, Riezman H. Distribution and functions of sterols and sphingolipids. Cold Spring Harb Perspect Biol. 2011 3. pii: a004762.PMID 21454248</ref>
	\| セラミドホスホエタノールアミン(CPE)はセラミドにリン酸を介してエタノールアミンが結合したものです。昆虫に多く見出されますが、バクテリアから原生生物、哺乳動物まで多くの生物に微量ですが存在します。植物や菌類には見いだされていません。セラミドアミノエチルホスホン酸(CAEP)はCPEと似た構造ですがC-P結合を持ち、原生生物、刺胞動物、軟体動物、棘皮動物などに存在します。
			Ceramide aminoethylphosphonate (CAEP) is similar to CPE but is formed by the C-P bonding. It is found in protozoa, cnidaria, mollusca, and echinodermata.<ref>Hori T, Itasaka O, Inoue H. Biochemistry of shellfish lipid. 3. Purification and elemental analysis of ceramide aminoethylphosphonate from Corbicula complex lipid mixtures. J Biochem. 1966 59:570-3. PMID 5962677</ref>
			\|
			セラミドホスホエタノールアミン(CPE)はセラミドにリン酸を介してエタノールアミンが結合したものです。昆虫に多く見出されますが、バクテリアから原生生物、哺乳動物まで多くの生物に微量ですが存在します。植物や菌類には見いだされていません。

			セラミドアミノエチルホスホン酸(CAEP)はCPEと似た構造ですがC-P結合を持ち、原生生物、刺胞動物、軟体動物、棘皮動物などに存在します。
	}}		}}

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	<references/>		<references/>

	==~~Glycosyl inositol phosphoceramide (~~GIPC~~) グリコシルイノシトールホスホセラミド~~==		=={{bilingual\|グリコシルイノシトールホスホセラミド\|GIPC}}==

	{{Twocolumn\|		{{Twocolumn\|

Dbmanager: /* Glycosyl inositol phosphoceramide (GIPC) グリコシルイノシトールホスホセラミド */

2017-06-06T13:34:50Z

Glycosyl inositol phosphoceramide (GIPC) グリコシルイノシトールホスホセラミド

← Older revision		Revision as of 22:34, 6 June 2017
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	{{Twocolumn\|		{{Twocolumn\|
	Glycosyl inositol phosphoceramides (GIPCs) were historically referred to as 'phytoglycolipids' (PGLs) for their abundance in plants and fungi.<ref>Carter HE, Celmer WD, Galanos DS, Gigg RH, Lands EM, Law JH, Mueller KL, Nakayama T, Tomizawa HH, Weber E. ~~1958.~~ Biochemistry of the sphingolipides. X. Phytoglycolipide, a complex phytosphingosine-containing lipide from plant seeds. Journal of the American Oil Chemists Society 35: 335–343　DOI 10.1007/BF02640547</ref><ref>Carter HE, Kisic A. “Countercurrent distribution of inosol lipids of plant seeds” J Lipid Res. 1969; 10:356-62. PMID 4307829</ref>		Glycosyl inositol phosphoceramides (GIPCs) were historically referred to as 'phytoglycolipids' (PGLs) for their abundance in plants and fungi.<ref>Carter HE, Celmer WD, Galanos DS, Gigg RH, Lands EM, Law JH, Mueller KL, Nakayama T, Tomizawa HH, Weber E. Biochemistry of the sphingolipides. X. Phytoglycolipide, a complex phytosphingosine-containing lipide from plant seeds. Journal of the American Oil Chemists Society 1958 35: 335–343　DOI 10.1007/BF02640547</ref><ref>Carter HE, Kisic A. “Countercurrent distribution of inosol lipids of plant seeds” J Lipid Res. 1969; 10:356-62. PMID 4307829</ref>
	Later found in bacteria, protista, and other animals (except chordata), PGLs are now called GIPCs. The structure is composed of ceramide with inositol phosphate (inositolphosphoceramide, IPC) and different sugars are attached.<ref>Buré C, Cacas JL, Mongrand S, Schmitter JM ~~(2014)~~ "Characterization of glycosyl inositol phosphoryl ceramides from plants and fungi by mass spectrometry" Anal Bioanal Chem. 406:995-1010. PMID 23887274</ref><ref>Gronnier J, Germain V, Gouguet P, Cacas JL, Mongrand S. ”GIPC: Glycosyl Inositol Phospho Ceramides, the major sphingolipids on earth”Plant Signal Behav. 2016 2;11(4):e1152438 PMID 27074617</ref>		Later found in bacteria, protista, and other animals (except chordata), PGLs are now called GIPCs. The structure is composed of ceramide with inositol phosphate (inositolphosphoceramide, IPC) and different sugars are attached.<ref>Buré C, Cacas JL, Mongrand S, Schmitter JM "Characterization of glycosyl inositol phosphoryl ceramides from plants and fungi by mass spectrometry" Anal Bioanal Chem. 2014 406:995-1010. PMID 23887274</ref><ref>Gronnier J, Germain V, Gouguet P, Cacas JL, Mongrand S. ”GIPC: Glycosyl Inositol Phospho Ceramides, the major sphingolipids on earth”Plant Signal Behav. 2016 2;11(4):e1152438 PMID 27074617</ref>

	===Classification===		===Classification===

Dbmanager: /* Ceramide phosphoethanolamine (CPE) and ceramide aminoethylphosphonate (CAEP) */

2016-06-07T12:48:04Z

Ceramide phosphoethanolamine (CPE) and ceramide aminoethylphosphonate (CAEP)

← Older revision		Revision as of 21:48, 7 June 2016
Line 36:		Line 36:
	<references/>		<references/>

	==Ceramide phosphoethanolamine (CPE) and ceramide aminoethylphosphonate (CAEP)==		==Ceramide phosphoethanolamine (CPE) and ceramide aminoethylphosphonate (CAEP)<br>セラミドホスホエタノールアミンとセラミドアミノエチルホスホン酸==

	{{Twocolumn\|		{{Twocolumn\|