https://lipidbank.jp/mediawiki/index.php?action=history&feed=atom&title=LBF20308PG03
LBF20308PG03 - Revision history
2026-04-30T01:07:21Z
Revision history for this page on the wiki
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https://lipidbank.jp/mediawiki/index.php?title=LBF20308PG03&diff=54042&oldid=prev
Editor at 03:43, 29 November 2010
2010-11-29T03:43:28Z
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|SysName=7- [cis-2- (3S-Hydroxyoctylidene) -3-oxo-4-cyclopenten-1R-yl] -<del style="font-weight: bold; text-decoration: none;">trans</del>-5-heptenoic acid</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|SysName=7- [cis-2- (3S-Hydroxyoctylidene) -3-oxo-4-cyclopenten-1R-yl] -<ins style="font-weight: bold; text-decoration: none;">cis</ins>-5-heptenoic acid</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Common Name=&&7- [2-(E)- (3S-Hydroxyoctylidene) -3-oxo-4-cyclopenten-1R-yl] -5-(Z) -heptenoic acid&&</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Common Name=&&7- [2-(E)- (3S-Hydroxyoctylidene) -3-oxo-4-cyclopenten-1R-yl] -5-(Z) -heptenoic acid&&</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Solubility=METHANOL[[Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713|{{RelationTable/GetFirstAuthor|Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713}}]]ETHANOL, CHLOROFORM, ETHYL ACETATE [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Solubility=METHANOL[[Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713|{{RelationTable/GetFirstAuthor|Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713}}]]ETHANOL, CHLOROFORM, ETHYL ACETATE [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
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https://lipidbank.jp/mediawiki/index.php?title=LBF20308PG03&diff=54041&oldid=prev
Editor at 09:03, 21 October 2010
2010-10-21T09:03:40Z
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|SysName=7- [2<del style="font-weight: bold; text-decoration: none;">-cis</del>- (3S-Hydroxyoctylidene) -3-oxo-4-cyclopenten-1R-yl] -5<del style="font-weight: bold; text-decoration: none;">-trans </del>-heptenoic acid</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|SysName=7- [<ins style="font-weight: bold; text-decoration: none;">cis-</ins>2- (3S-Hydroxyoctylidene) -3-oxo-4-cyclopenten-1R-yl] <ins style="font-weight: bold; text-decoration: none;">-trans</ins>-5-heptenoic acid</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Common Name=&&7- [2-(E)- (3S-Hydroxyoctylidene) -3-oxo-4-cyclopenten-1R-yl] -5-(Z) -heptenoic acid&&</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Common Name=&&7- [2-(E)- (3S-Hydroxyoctylidene) -3-oxo-4-cyclopenten-1R-yl] -5-(Z) -heptenoic acid&&</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Solubility=METHANOL[[Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713|{{RelationTable/GetFirstAuthor|Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713}}]]ETHANOL, CHLOROFORM, ETHYL ACETATE [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Solubility=METHANOL[[Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713|{{RelationTable/GetFirstAuthor|Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713}}]]ETHANOL, CHLOROFORM, ETHYL ACETATE [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
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Editor
https://lipidbank.jp/mediawiki/index.php?title=LBF20308PG03&diff=54040&oldid=prev
Editor at 06:39, 28 May 2010
2010-05-28T06:39:58Z
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|SysName=7- [2-cis- (3S-Hydroxyoctylidene) -3-oxo-4-cyclopenten-1R-yl] -5-trans -heptenoic acid</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|SysName=7- [2-cis- (3S-Hydroxyoctylidene) -3-oxo-4-cyclopenten-1R-yl] -5-trans -heptenoic acid</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|Common Name=&&7- [2(E)- (3S-Hydroxyoctylidene) -3-oxo-4-cyclopenten-1R-yl] -5(Z) -heptenoic acid&&</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|Common Name=&&7- [2<ins style="font-weight: bold; text-decoration: none;">-</ins>(E)- (3S-Hydroxyoctylidene) -3-oxo-4-cyclopenten-1R-yl] -5<ins style="font-weight: bold; text-decoration: none;">-</ins>(Z) -heptenoic acid&&</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Solubility=METHANOL[[Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713|{{RelationTable/GetFirstAuthor|Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713}}]]ETHANOL, CHLOROFORM, ETHYL ACETATE [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Solubility=METHANOL[[Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713|{{RelationTable/GetFirstAuthor|Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713}}]]ETHANOL, CHLOROFORM, ETHYL ACETATE [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Mass Spectra=m/e 334(M^+ ), 316, 245, 236 [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Mass Spectra=m/e 334(M^+ ), 316, 245, 236 [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
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Editor
https://lipidbank.jp/mediawiki/index.php?title=LBF20308PG03&diff=54039&oldid=prev
Editor at 06:39, 28 May 2010
2010-05-28T06:39:30Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 15:39, 28 May 2010</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|LipidMaps=-</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|LipidMaps=-</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|SysName=7- [ 2 <del style="font-weight: bold; text-decoration: none;">(E) </del>- (<del style="font-weight: bold; text-decoration: none;">3 (S) </del>-Hydroxyoctylidene) -3-oxo-4-cyclopenten-<del style="font-weight: bold; text-decoration: none;">1 (R) </del>-yl ] -5 <del style="font-weight: bold; text-decoration: none;">(Z) </del>-heptenoic acid</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|SysName=7- [2<ins style="font-weight: bold; text-decoration: none;">-cis</ins>- (<ins style="font-weight: bold; text-decoration: none;">3S</ins>-Hydroxyoctylidene) -3-oxo-4-cyclopenten-<ins style="font-weight: bold; text-decoration: none;">1R</ins>-yl] -5<ins style="font-weight: bold; text-decoration: none;">-trans </ins>-heptenoic acid</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|Common Name=&&7- [ 2 (E) - (<del style="font-weight: bold; text-decoration: none;">3 (S) </del>-Hydroxyoctylidene) -3-oxo-4-cyclopenten-<del style="font-weight: bold; text-decoration: none;">1 (R) </del>-yl ] -5 (Z) -heptenoic acid&&</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|Common Name=&&7- [2(E)- (<ins style="font-weight: bold; text-decoration: none;">3S</ins>-Hydroxyoctylidene) -3-oxo-4-cyclopenten-<ins style="font-weight: bold; text-decoration: none;">1R</ins>-yl] -5(Z) -heptenoic acid&&</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Solubility=METHANOL[[Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713|{{RelationTable/GetFirstAuthor|Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713}}]]ETHANOL, CHLOROFORM, ETHYL ACETATE [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Solubility=METHANOL[[Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713|{{RelationTable/GetFirstAuthor|Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713}}]]ETHANOL, CHLOROFORM, ETHYL ACETATE [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Mass Spectra=m/e 334(M^+ ), 316, 245, 236 [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Mass Spectra=m/e 334(M^+ ), 316, 245, 236 [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
</table>
Editor
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Editor at 21:00, 14 April 2010
2010-04-14T21:00:00Z
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<td colspan="1" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 06:00, 15 April 2010</td>
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Editor
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Editor at 10:00, 25 February 2010
2010-02-25T10:00:10Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 19:00, 25 February 2010</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Solubility=METHANOL[[Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713|{{RelationTable/GetFirstAuthor|Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713}}]]ETHANOL, CHLOROFORM, ETHYL ACETATE [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Solubility=METHANOL[[Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713|{{RelationTable/GetFirstAuthor|Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713}}]]ETHANOL, CHLOROFORM, ETHYL ACETATE [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Mass Spectra=m/e 334(M^+ ), 316, 245, 236 [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Mass Spectra=m/e 334(M^+ ), 316, 245, 236 [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|UV Spectra= lambda ^<del style="font-weight: bold; text-decoration: none;">E_m _a _x </del>= 244( epsilon 6100)nm [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|UV Spectra= lambda ^<ins style="font-weight: bold; text-decoration: none;">{EtOH}_{max} </ins>= 244( epsilon 6100)nm [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|IR Spectra= nu : 2930, 1700, 1640, 1580, 1232, 028 cm^- <del style="font-weight: bold; text-decoration: none;">^</del>1 <del style="font-weight: bold; text-decoration: none;"> </del>[[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|IR Spectra= nu : 2930, 1700, 1640, 1580, 1232, 028 cm^<ins style="font-weight: bold; text-decoration: none;">{</ins>-1<ins style="font-weight: bold; text-decoration: none;">} </ins>[[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|NMR Spectra=^1 H-NMR(CDCl_3 ) : delta 7.5(dd, 1H, 9-CH), 6.56(t, 1H, 13-CH), 6.35(dd,1 H, 10-CH), 5.48(m, 2H, 5,6-CH), 3.88(m, 1H, 15-CH), 3.44(m, 1H, 8-CH) [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|NMR Spectra=^1 H-NMR(CDCl_3 ) : delta 7.5(dd, 1H, 9-CH), 6.56(t, 1H, 13-CH), 6.35(dd,1 H, 10-CH), 5.48(m, 2H, 5,6-CH), 3.88(m, 1H, 15-CH), 3.44(m, 1H, 8-CH) [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Source=</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Source=</div></td></tr>
</table>
Editor
https://lipidbank.jp/mediawiki/index.php?title=LBF20308PG03&diff=54036&oldid=prev
Editor at 14:00, 19 February 2010
2010-02-19T14:00:10Z
<p></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 23:00, 19 February 2010</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l10">Line 10:</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Solubility=METHANOL[[Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713|{{RelationTable/GetFirstAuthor|Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713}}]]ETHANOL, CHLOROFORM, ETHYL ACETATE [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Solubility=METHANOL[[Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713|{{RelationTable/GetFirstAuthor|Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713}}]]ETHANOL, CHLOROFORM, ETHYL ACETATE [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Mass Spectra=m/e 334(M^+ ), 316, 245, 236 [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Mass Spectra=m/e 334(M^+ ), 316, 245, 236 [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|UV Spectra=lambda ^E_m _a _x = 244(epsilon 6100)nm [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|UV Spectra= lambda <ins style="font-weight: bold; text-decoration: none;"> </ins>^E_m _a _x = 244( epsilon <ins style="font-weight: bold; text-decoration: none;"> </ins>6100)nm [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|IR Spectra=nu : 2930, 1700, 1640, 1580, 1232, 028 cm^- ^1 [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|IR Spectra= nu <ins style="font-weight: bold; text-decoration: none;"> </ins>: 2930, 1700, 1640, 1580, 1232, 028 cm^- ^1 [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|NMR Spectra=^1 H-NMR(CDCl_3 ) : delta 7.5(dd, 1H, 9-CH), 6.56(t, 1H, 13-CH), 6.35(dd,1 H, 10-CH), 5.48(m, 2H, 5,6-CH), 3.88(m, 1H, 15-CH), 3.44(m, 1H, 8-CH) [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|NMR Spectra=^1 H-NMR(CDCl_3 ) : <ins style="font-weight: bold; text-decoration: none;"> </ins>delta <ins style="font-weight: bold; text-decoration: none;"> </ins>7.5(dd, 1H, 9-CH), 6.56(t, 1H, 13-CH), 6.35(dd,1 H, 10-CH), 5.48(m, 2H, 5,6-CH), 3.88(m, 1H, 15-CH), 3.44(m, 1H, 8-CH) [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Source=</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Source=</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Chemical Synthesis=[[Reference:Bundy_GL:Morton_DR:Peterson_DC:Nishizawa_EE:Miller_WL:,J. Med. Chem.,1983,26,790|{{RelationTable/GetFirstAuthor|Reference:Bundy_GL:Morton_DR:Peterson_DC:Nishizawa_EE:Miller_WL:,J. Med. Chem.,1983,26,790}}]] {{Image200|LBF20308PG03FT0001.gif}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Chemical Synthesis=[[Reference:Bundy_GL:Morton_DR:Peterson_DC:Nishizawa_EE:Miller_WL:,J. Med. Chem.,1983,26,790|{{RelationTable/GetFirstAuthor|Reference:Bundy_GL:Morton_DR:Peterson_DC:Nishizawa_EE:Miller_WL:,J. Med. Chem.,1983,26,790}}]] {{Image200|LBF20308PG03FT0001.gif}}</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|Metabolism=In human plasma prostaglandin D2 is dehydrated and converted to 9-deoxy-<del style="font-weight: bold; text-decoration: none;">Delta9</del>,12-13,14-dihydro-prostaglandin D2 (<del style="font-weight: bold; text-decoration: none;">Delta12</del>-prostaglandin J2) catalyzedby serum albumin [[Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739|{{RelationTable/GetFirstAuthor|Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739}}]].</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|Metabolism=In human plasma prostaglandin D2 is dehydrated and converted to 9-deoxy- <ins style="font-weight: bold; text-decoration: none;">Delta 9</ins>,12-13,14-dihydro-prostaglandin D2 ( <ins style="font-weight: bold; text-decoration: none;">Delta 12</ins>-prostaglandin J2) catalyzedby serum albumin [[Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739|{{RelationTable/GetFirstAuthor|Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739}}]].</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|Symbol=<del style="font-weight: bold; text-decoration: none;">Delta12</del>-PGJ2</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|Symbol= <ins style="font-weight: bold; text-decoration: none;">Delta 12</ins>-PGJ2</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|Biological Activity=<del style="font-weight: bold; text-decoration: none;">Delta12</del>-Prostaglandin J2 is considered to be an ultimate metabolite of prostaglandin D2 with anti-tumor and anti-viral activities [[Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739|{{RelationTable/GetFirstAuthor|Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739}}]]. The compound has no cell surface recptor, but is transported into cells and then inot nuclei. The biological activities of <del style="font-weight: bold; text-decoration: none;">Delta12</del>-prostaglandin J2 are due to the syntheses of various proteins including heat shock proteins, gamma-glutamylcysteine synthetase, collagen and heme oxygenase [[Reference:Negishi_M:Koizumi_T:Ichikawa_A:,J. Lipid Mediat. Cell Signal.,1995,12,443|{{RelationTable/GetFirstAuthor|Reference:Negishi_M:Koizumi_T:Ichikawa_A:,J. Lipid Mediat. Cell Signal.,1995,12,443}}]].</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|Biological Activity= <ins style="font-weight: bold; text-decoration: none;">Delta 12</ins>-Prostaglandin J2 is considered to be an ultimate metabolite of prostaglandin D2 with anti-tumor and anti-viral activities [[Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739|{{RelationTable/GetFirstAuthor|Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739}}]]. The compound has no cell surface recptor, but is transported into cells and then inot nuclei. The biological activities of <ins style="font-weight: bold; text-decoration: none;"> Delta 12</ins>-prostaglandin J2 are due to the syntheses of various proteins including heat shock proteins, <ins style="font-weight: bold; text-decoration: none;"> </ins>gamma -glutamylcysteine synthetase, collagen and heme oxygenase [[Reference:Negishi_M:Koizumi_T:Ichikawa_A:,J. Lipid Mediat. Cell Signal.,1995,12,443|{{RelationTable/GetFirstAuthor|Reference:Negishi_M:Koizumi_T:Ichikawa_A:,J. Lipid Mediat. Cell Signal.,1995,12,443}}]].</div></td></tr>
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https://lipidbank.jp/mediawiki/index.php?title=LBF20308PG03&diff=54035&oldid=prev
Editor at 14:00, 19 February 2010
2010-02-19T14:00:00Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 23:00, 19 February 2010</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l9">Line 9:</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Common Name=&&7- [ 2 (E) - (3 (S) -Hydroxyoctylidene) -3-oxo-4-cyclopenten-1 (R) -yl ] -5 (Z) -heptenoic acid&&</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Common Name=&&7- [ 2 (E) - (3 (S) -Hydroxyoctylidene) -3-oxo-4-cyclopenten-1 (R) -yl ] -5 (Z) -heptenoic acid&&</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Solubility=METHANOL[[Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713|{{RelationTable/GetFirstAuthor|Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713}}]]ETHANOL, CHLOROFORM, ETHYL ACETATE [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Solubility=METHANOL[[Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713|{{RelationTable/GetFirstAuthor|Reference:Fitzpatrick_FA:Wynalda_MA:,J. Biol. Chem.,1983,258,11713}}]]ETHANOL, CHLOROFORM, ETHYL ACETATE [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|Mass Spectra=m/e 334(M<del style="font-weight: bold; text-decoration: none;"><SUP><FONT SIZE=-1></del>+<del style="font-weight: bold; text-decoration: none;"></FONT></SUP></del>), 316, 245, 236 [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|Mass Spectra=m/e 334(M<ins style="font-weight: bold; text-decoration: none;">^</ins>+ ), 316, 245, 236 [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|UV Spectra=<del style="font-weight: bold; text-decoration: none;"><FONT FACE="Symbol">l</FONT> <SUP><FONT SIZE=-1>E</FONT></SUP><SUP><FONT SIZE=-1>t</FONT></SUP><SUP><FONT SIZE=-1>O</FONT></SUP><SUP><FONT SIZE=-1>H</FONT></SUP><SUB><FONT SIZE=-1>m</FONT></SUB><SUB><FONT SIZE=-1>a</FONT></SUB><SUB><FONT SIZE=-1>x</FONT></SUB> </del>= 244(<del style="font-weight: bold; text-decoration: none;"><FONT FACE="Symbol">e</FONT> </del>6100)nm [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|UV Spectra=<ins style="font-weight: bold; text-decoration: none;">lambda ^E_m _a _x </ins>= 244(<ins style="font-weight: bold; text-decoration: none;">epsilon </ins>6100)nm [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|IR Spectra=<del style="font-weight: bold; text-decoration: none;"><FONT FACE="Symbol">n</FONT> </del>: 2930, 1700, 1640, 1580, 1232, 028 cm<del style="font-weight: bold; text-decoration: none;"><SUP><FONT SIZE=-1>-</FONT></SUP><SUP><FONT SIZE=</del>-1<del style="font-weight: bold; text-decoration: none;">>1</FONT></SUP> </del>[[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|IR Spectra=<ins style="font-weight: bold; text-decoration: none;">nu </ins>: 2930, 1700, 1640, 1580, 1232, 028 cm<ins style="font-weight: bold; text-decoration: none;">^</ins>- <ins style="font-weight: bold; text-decoration: none;">^</ins>1 <ins style="font-weight: bold; text-decoration: none;"> </ins>[[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|NMR Spectra=<del style="font-weight: bold; text-decoration: none;"><SUP><FONT SIZE=-1></del>1<del style="font-weight: bold; text-decoration: none;"></FONT></SUP></del>H-NMR(<del style="font-weight: bold; text-decoration: none;">CDCl<SUB><FONT SIZE=-1>3</FONT></SUB></del>) : <del style="font-weight: bold; text-decoration: none;"><FONT FACE="Symbol">d</FONT> </del>7.5(dd, 1H, 9-CH), 6.56(t, 1H, 13-CH), 6.35(dd,1 H, 10-CH), 5.48(m, 2H, 5,6-CH), 3.88(m, 1H, 15-CH), 3.44(m, 1H, 8-CH) [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|NMR Spectra=<ins style="font-weight: bold; text-decoration: none;">^</ins>1 H-NMR(<ins style="font-weight: bold; text-decoration: none;">CDCl_3 </ins>) : <ins style="font-weight: bold; text-decoration: none;">delta </ins>7.5(dd, 1H, 9-CH), 6.56(t, 1H, 13-CH), 6.35(dd,1 H, 10-CH), 5.48(m, 2H, 5,6-CH), 3.88(m, 1H, 15-CH), 3.44(m, 1H, 8-CH) [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Source=</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Source=</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Chemical Synthesis=[[Reference:Bundy_GL:Morton_DR:Peterson_DC:Nishizawa_EE:Miller_WL:,J. Med. Chem.,1983,26,790|{{RelationTable/GetFirstAuthor|Reference:Bundy_GL:Morton_DR:Peterson_DC:Nishizawa_EE:Miller_WL:,J. Med. Chem.,1983,26,790}}]] {{Image200|LBF20308PG03FT0001.gif}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Chemical Synthesis=[[Reference:Bundy_GL:Morton_DR:Peterson_DC:Nishizawa_EE:Miller_WL:,J. Med. Chem.,1983,26,790|{{RelationTable/GetFirstAuthor|Reference:Bundy_GL:Morton_DR:Peterson_DC:Nishizawa_EE:Miller_WL:,J. Med. Chem.,1983,26,790}}]] {{Image200|LBF20308PG03FT0001.gif}}</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|Metabolism=In human plasma prostaglandin D2 is dehydrated and converted to 9-deoxy-<del style="font-weight: bold; text-decoration: none;"><FONT FACE="Symbol">D</FONT>9</del>,12-13,14-dihydro-prostaglandin D2 (<del style="font-weight: bold; text-decoration: none;"><FONT FACE="Symbol">D</FONT>12</del>-prostaglandin J2) catalyzedby serum albumin [[Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739|{{RelationTable/GetFirstAuthor|Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739}}]].</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|Metabolism=In human plasma prostaglandin D2 is dehydrated and converted to 9-deoxy-<ins style="font-weight: bold; text-decoration: none;">Delta9</ins>,12-13,14-dihydro-prostaglandin D2 (<ins style="font-weight: bold; text-decoration: none;">Delta12</ins>-prostaglandin J2) catalyzedby serum albumin [[Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739|{{RelationTable/GetFirstAuthor|Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739}}]].</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|Symbol=<del style="font-weight: bold; text-decoration: none;"><FONT FACE="Symbol">D</FONT>12</del>-PGJ2</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|Symbol=<ins style="font-weight: bold; text-decoration: none;">Delta12</ins>-PGJ2</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|Biological Activity=<del style="font-weight: bold; text-decoration: none;"><FONT FACE="Symbol">D</FONT>12</del>-Prostaglandin J2 is considered to be an ultimate metabolite of prostaglandin D2 with anti-tumor and anti-viral activities [[Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739|{{RelationTable/GetFirstAuthor|Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739}}]]. The compound has no cell surface recptor, but is transported into cells and then inot nuclei. The biological activities of <del style="font-weight: bold; text-decoration: none;"><FONT FACE="Symbol">D</FONT>12</del>-prostaglandin J2 are due to the syntheses of various proteins including heat shock proteins, <del style="font-weight: bold; text-decoration: none;"><FONT FACE="Symbol">g</FONT></del>-glutamylcysteine synthetase, collagen and heme oxygenase [[Reference:Negishi_M:Koizumi_T:Ichikawa_A:,J. Lipid Mediat. Cell Signal.,1995,12,443|{{RelationTable/GetFirstAuthor|Reference:Negishi_M:Koizumi_T:Ichikawa_A:,J. Lipid Mediat. Cell Signal.,1995,12,443}}]].</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|Biological Activity=<ins style="font-weight: bold; text-decoration: none;">Delta12</ins>-Prostaglandin J2 is considered to be an ultimate metabolite of prostaglandin D2 with anti-tumor and anti-viral activities [[Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739|{{RelationTable/GetFirstAuthor|Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739}}]]. The compound has no cell surface recptor, but is transported into cells and then inot nuclei. The biological activities of <ins style="font-weight: bold; text-decoration: none;">Delta12</ins>-prostaglandin J2 are due to the syntheses of various proteins including heat shock proteins, <ins style="font-weight: bold; text-decoration: none;">gamma</ins>-glutamylcysteine synthetase, collagen and heme oxygenase [[Reference:Negishi_M:Koizumi_T:Ichikawa_A:,J. Lipid Mediat. Cell Signal.,1995,12,443|{{RelationTable/GetFirstAuthor|Reference:Negishi_M:Koizumi_T:Ichikawa_A:,J. Lipid Mediat. Cell Signal.,1995,12,443}}]].</div></td></tr>
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Editor
https://lipidbank.jp/mediawiki/index.php?title=LBF20308PG03&diff=54034&oldid=prev
Editor at 21:00, 6 January 2010
2010-01-06T21:00:00Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 06:00, 7 January 2010</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Chemical Synthesis=[[Reference:Bundy_GL:Morton_DR:Peterson_DC:Nishizawa_EE:Miller_WL:,J. Med. Chem.,1983,26,790|{{RelationTable/GetFirstAuthor|Reference:Bundy_GL:Morton_DR:Peterson_DC:Nishizawa_EE:Miller_WL:,J. Med. Chem.,1983,26,790}}]] {{Image200|LBF20308PG03FT0001.gif}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Chemical Synthesis=[[Reference:Bundy_GL:Morton_DR:Peterson_DC:Nishizawa_EE:Miller_WL:,J. Med. Chem.,1983,26,790|{{RelationTable/GetFirstAuthor|Reference:Bundy_GL:Morton_DR:Peterson_DC:Nishizawa_EE:Miller_WL:,J. Med. Chem.,1983,26,790}}]] {{Image200|LBF20308PG03FT0001.gif}}</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Metabolism=In human plasma prostaglandin D2 is dehydrated and converted to 9-deoxy-<FONT FACE="Symbol">D</FONT>9,12-13,14-dihydro-prostaglandin D2 (<FONT FACE="Symbol">D</FONT>12-prostaglandin J2) catalyzedby serum albumin [[Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739|{{RelationTable/GetFirstAuthor|Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739}}]].</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Metabolism=In human plasma prostaglandin D2 is dehydrated and converted to 9-deoxy-<FONT FACE="Symbol">D</FONT>9,12-13,14-dihydro-prostaglandin D2 (<FONT FACE="Symbol">D</FONT>12-prostaglandin J2) catalyzedby serum albumin [[Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739|{{RelationTable/GetFirstAuthor|Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739}}]].</div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|Symbol=<FONT FACE="Symbol">D</FONT>12-PGJ2</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|Biological Activity=<FONT FACE="Symbol">D</FONT>12-Prostaglandin J2 is considered to be an ultimate metabolite of prostaglandin D2 with anti-tumor and anti-viral activities [[Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739|{{RelationTable/GetFirstAuthor|Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739}}]]. The compound has no cell surface recptor, but is transported into cells and then inot nuclei. The biological activities of <FONT FACE="Symbol">D</FONT>12-prostaglandin J2 are due to the syntheses of various proteins including heat shock proteins, <FONT FACE="Symbol">g</FONT>-glutamylcysteine synthetase, collagen and heme oxygenase [[Reference:Negishi_M:Koizumi_T:Ichikawa_A:,J. Lipid Mediat. Cell Signal.,1995,12,443|{{RelationTable/GetFirstAuthor|Reference:Negishi_M:Koizumi_T:Ichikawa_A:,J. Lipid Mediat. Cell Signal.,1995,12,443}}]].</ins></div></td></tr>
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Editor
https://lipidbank.jp/mediawiki/index.php?title=LBF20308PG03&diff=54033&oldid=prev
Editor at 11:55, 25 November 2009
2009-11-25T11:55:00Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 20:55, 25 November 2009</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l14">Line 14:</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|NMR Spectra=<SUP><FONT SIZE=-1>1</FONT></SUP>H-NMR(CDCl<SUB><FONT SIZE=-1>3</FONT></SUB>) : <FONT FACE="Symbol">d</FONT> 7.5(dd, 1H, 9-CH), 6.56(t, 1H, 13-CH), 6.35(dd,1 H, 10-CH), 5.48(m, 2H, 5,6-CH), 3.88(m, 1H, 15-CH), 3.44(m, 1H, 8-CH) [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|NMR Spectra=<SUP><FONT SIZE=-1>1</FONT></SUP>H-NMR(CDCl<SUB><FONT SIZE=-1>3</FONT></SUB>) : <FONT FACE="Symbol">d</FONT> 7.5(dd, 1H, 9-CH), 6.56(t, 1H, 13-CH), 6.35(dd,1 H, 10-CH), 5.48(m, 2H, 5,6-CH), 3.88(m, 1H, 15-CH), 3.44(m, 1H, 8-CH) [[Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317|{{RelationTable/GetFirstAuthor|Reference:Kikawa_Y:Narumiya_S:Fukushima_M:Wakatsuka_H:Hayaishi_O:,Proc. Natl. Acad. Sci. U. S. A.,1984,81,1317}}]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Source=</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Source=</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|Chemical Synthesis=[[Reference:Bundy_GL:Morton_DR:Peterson_DC:Nishizawa_EE:Miller_WL:,J. Med. Chem.,1983,26,790|{{RelationTable/GetFirstAuthor|Reference:Bundy_GL:Morton_DR:Peterson_DC:Nishizawa_EE:Miller_WL:,J. Med. Chem.,1983,26,790}}]]<del style="font-weight: bold; text-decoration: none;">;> </del>{{Image200|LBF20308PG03FT0001.gif}}</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|Chemical Synthesis=[[Reference:Bundy_GL:Morton_DR:Peterson_DC:Nishizawa_EE:Miller_WL:,J. Med. Chem.,1983,26,790|{{RelationTable/GetFirstAuthor|Reference:Bundy_GL:Morton_DR:Peterson_DC:Nishizawa_EE:Miller_WL:,J. Med. Chem.,1983,26,790}}]] {{Image200|LBF20308PG03FT0001.gif}}</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|Metabolism=In human plasma prostaglandin D2 is dehydrated and converted to 9-deoxy-<FONT FACE="Symbol">D</FONT>9,12-13,14-dihydro-prostaglandin D2 (<FONT FACE="Symbol">D</FONT>12-prostaglandin J2) catalyzedby serum albumin [[Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739|{{RelationTable/GetFirstAuthor|Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739}}]]<del style="font-weight: bold; text-decoration: none;">;></del>.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|Metabolism=In human plasma prostaglandin D2 is dehydrated and converted to 9-deoxy-<FONT FACE="Symbol">D</FONT>9,12-13,14-dihydro-prostaglandin D2 (<FONT FACE="Symbol">D</FONT>12-prostaglandin J2) catalyzedby serum albumin [[Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739|{{RelationTable/GetFirstAuthor|Reference:Narumiya_S:Fukushima_M:,Biochem. Biophys. Res. Commun.,1985,127,739}}]].</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Lipid/Footer}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Lipid/Footer}}</div></td></tr>
</table>
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