https://lipidbank.jp/mediawiki/index.php?action=history&feed=atom&title=LBF20406LT20 2026-04-30T04:10:27Z Revision history for this page on the wiki MediaWiki 1.43.0 https://lipidbank.jp/mediawiki/index.php?title=LBF20406LT20&diff=55912&oldid=prev 2011-02-21T05:01:51Z

<p>New page: {{Lipid/Header}} {{Hierarchy|{{PAGENAME}}}} {{Metabolite |LipidBank=XPR3501 |LipidMaps=LMFA03020009 |SysName=5S-Hydroxy-6R-S-glutamylcysteinyl- (trans-7,trans-9,cis-11,cis-14) -eicosatet...</p> <p><b>New page</b></p><div>{{Lipid/Header}}<br /> <br /> {{Hierarchy|{{PAGENAME}}}}<br /> <br /> {{Metabolite<br /> |LipidBank=XPR3501<br /> |LipidMaps=LMFA03020009<br /> |SysName=5S-Hydroxy-6R-S-glutamylcysteinyl- (trans-7,trans-9,cis-11,cis-14) -eicosatetraenoic acid<br /> |Common Name=&amp;&amp;Leukotriene F_4&amp;&amp;5S-Hydroxy-6R-S-glutamylcysteinyl- (7E,9E,11Z,14Z) -eicosatetraenoic acid&amp;&amp;5 (S) -Hydroxy-6 (R) -S-glutamylcysteinyleicosa-7 (E) ,9 (E) ,11 (Z) ,14 (Z) -tetraenoic acid&amp;&amp;<br /> |Mass Spectra=N-TRIFLUOROACETYL METHYL ESTER ; 701(M^+ ), 688, 675, 674, 662, 657, 649, 648, 578, 550, 465 [[Reference:Okuyama_S:Miyamoto_S:Shimoji_K:Konishi_Y:Fukushima_D:Niwa_H:Arai_Y:Toda_M:Hayashi_M:,Chem. Pharm. Bull. (Tokyo),1982,30,2453|{{RelationTable/GetFirstAuthor|Reference:Okuyama_S:Miyamoto_S:Shimoji_K:Konishi_Y:Fukushima_D:Niwa_H:Arai_Y:Toda_M:Hayashi_M:,Chem. Pharm. Bull. (Tokyo),1982,30,2453}}]]<br /> |UV Spectra= lambda = 270sh, 280( epsilon 40000), 290sh nm [[Reference:Denis_D:Charleson_S:Rackham_A:Jones_TR:Ford-Hutchinson_AW:Lord_A:Cirino_M:Girard_Y:Larue_M:Rokach_J:,Prostaglandins,1982,24,801|{{RelationTable/GetFirstAuthor|Reference:Denis_D:Charleson_S:Rackham_A:Jones_TR:Ford-Hutchinson_AW:Lord_A:Cirino_M:Girard_Y:Larue_M:Rokach_J:,Prostaglandins,1982,24,801}}]]<br /> |IR Spectra=N-TRIFLUOROACETYL METHYL ESTER ; nu 3300, 1720, 1650, 1200, 985cm^{-1} [[Reference:Okuyama_S:Miyamoto_S:Shimoji_K:Konishi_Y:Fukushima_D:Niwa_H:Arai_Y:Toda_M:Hayashi_M:,Chem. Pharm. Bull. (Tokyo),1982,30,2453|{{RelationTable/GetFirstAuthor|Reference:Okuyama_S:Miyamoto_S:Shimoji_K:Konishi_Y:Fukushima_D:Niwa_H:Arai_Y:Toda_M:Hayashi_M:,Chem. Pharm. Bull. (Tokyo),1982,30,2453}}]]<br /> |NMR Spectra=N-TRIFLUOROACETYL METHYL ESTER ; ^1 H-NMR(CDCl_3 ) : delta 6.9-5.2(m, 8H), 5.0-4.5(m, 2H), 3.8-3.6(m, 1H, 5-CH), 3.79(s, 3H, OCH_3 ), 3.76(s, 3H, OCH_3 ), 3.67(s, 3H, OCH_3 ), 3.6-3.3(m, 1H, 6-CH), 3.1-2.7(m, 4H), 0.9(t, J=7Hz, 3H, 20-CH_3 ) [[Reference:Okuyama_S:Miyamoto_S:Shimoji_K:Konishi_Y:Fukushima_D:Niwa_H:Arai_Y:Toda_M:Hayashi_M:,Chem. Pharm. Bull. (Tokyo),1982,30,2453|{{RelationTable/GetFirstAuthor|Reference:Okuyama_S:Miyamoto_S:Shimoji_K:Konishi_Y:Fukushima_D:Niwa_H:Arai_Y:Toda_M:Hayashi_M:,Chem. Pharm. Bull. (Tokyo),1982,30,2453}}]]<br /> |Source=<br /> |Chemical Synthesis=&lt;!--1066--&gt; {{Image200|LBF20406SF07FT0001.gif}}<br /> |Metabolism=Leukotriene E4 is transformed to leukotriene F4 by gamma -glultamyltransferase in the presence of glutathione [[Reference:Hammarstrom_S:Orning_L:Bernstrom_K:,Mol. Cell. Biochem.,1985,69,7|{{RelationTable/GetFirstAuthor|Reference:Hammarstrom_S:Orning_L:Bernstrom_K:,Mol. Cell. Biochem.,1985,69,7}}]].<br /> |Symbol=LTF4<br /> }}<br /> <br /> {{Lipid/Footer}}</div>

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