https://lipidbank.jp/mediawiki/index.php?action=history&feed=atom&title=LBF20503LT01 2026-04-30T02:45:47Z Revision history for this page on the wiki MediaWiki 1.43.0 https://lipidbank.jp/mediawiki/index.php?title=LBF20503LT01&diff=81370&oldid=prev 2014-01-17T00:00:00Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 09:00, 17 January 2014</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l17">Line 17:</td> <td colspan="2" class="diff-lineno">Line 17:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Symbol=LTB5</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Symbol=LTB5</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Biological Activity=Leukotriene B5 is about 1/30 as active as leukotriene B4 in stimulating aggregation of rat neutrophils, migration and lysosomal enzyme release of human polymorphonuclear leukocytes, and bradykinin-induced vascular permeability [[Reference:Terano_T:Salmon_JA:Moncada_S:,Prostaglandins,1984,27,217|{{RelationTable/GetFirstAuthor|Reference:Terano_T:Salmon_JA:Moncada_S:,Prostaglandins,1984,27,217}}]]. Leukotriene B5 is much less active than B4 to increase intracellular calciuim level in human neutrophils [[Reference:Seya_A:Terano_T:Tamura_Y:Yoshida_S:,Prostaglandins Leukot. Essent. Fatty Acids,1988,34,47|{{RelationTable/GetFirstAuthor|Reference:Seya_A:Terano_T:Tamura_Y:Yoshida_S:,Prostaglandins Leukot. Essent. Fatty Acids,1988,34,47}}]].</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Biological Activity=Leukotriene B5 is about 1/30 as active as leukotriene B4 in stimulating aggregation of rat neutrophils, migration and lysosomal enzyme release of human polymorphonuclear leukocytes, and bradykinin-induced vascular permeability [[Reference:Terano_T:Salmon_JA:Moncada_S:,Prostaglandins,1984,27,217|{{RelationTable/GetFirstAuthor|Reference:Terano_T:Salmon_JA:Moncada_S:,Prostaglandins,1984,27,217}}]]. Leukotriene B5 is much less active than B4 to increase intracellular calciuim level in human neutrophils [[Reference:Seya_A:Terano_T:Tamura_Y:Yoshida_S:,Prostaglandins Leukot. Essent. Fatty Acids,1988,34,47|{{RelationTable/GetFirstAuthor|Reference:Seya_A:Terano_T:Tamura_Y:Yoshida_S:,Prostaglandins Leukot. Essent. Fatty Acids,1988,34,47}}]].</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">}}</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{MassbankSpectra|</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">UT000298</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">UT000299</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">UT000300</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">UT000301</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">UT000302</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">UT000303</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">UT000304</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">UT000305</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">UT000306</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Lipid/Footer}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Lipid/Footer}}</div></td></tr> <!-- diff cache key wikidb:diff:1.41:old-56378:rev-81370:php=table --> </table>

Editor https://lipidbank.jp/mediawiki/index.php?title=LBF20503LT01&diff=56378&oldid=prev 2010-10-22T02:54:25Z

<p>New page: {{Lipid/Header}} {{Hierarchy|{{PAGENAME}}}} {{Metabolite |LipidBank=XPR4102 |LipidMaps=LMFA03020010 |SysName=(5S,12R) -Dihydroxy- (cis-6,trans-8,trans-10,cis-14,cis-17) -eicosapentaenoic...</p> <p><b>New page</b></p><div>{{Lipid/Header}}<br /> <br /> {{Hierarchy|{{PAGENAME}}}}<br /> <br /> {{Metabolite<br /> |LipidBank=XPR4102<br /> |LipidMaps=LMFA03020010<br /> |SysName=(5S,12R) -Dihydroxy- (cis-6,trans-8,trans-10,cis-14,cis-17) -eicosapentaenoic acid<br /> |Common Name=&amp;&amp;Leukotriene B_5&amp;&amp;(5S,12R) -Dihydroxy- (6Z,8E,10E,14Z,17Z) -eicosapentaenoic acid&amp;&amp;<br /> |Solubility=METHANOL [[Reference:Corey_EJ:Pyne_SG:Su_W:,Tetrah. Lett.,1983,24,4883|{{RelationTable/GetFirstAuthor|Reference:Corey_EJ:Pyne_SG:Su_W:,Tetrah. Lett.,1983,24,4883}}]]<br /> |Mass Spectra=METHYL ESTER TRIMETHYLSILYL ETHER M/E, 492(M^+ ), 477, 461, 402, 391, 383,293, 267, 229, 217, 203 [[Reference:Murphy_RC:Pickett_WC:Culp_BR:Lands_WE:,Prostaglandins,1981,22,613|{{RelationTable/GetFirstAuthor|Reference:Murphy_RC:Pickett_WC:Culp_BR:Lands_WE:,Prostaglandins,1981,22,613}}]]<br /> |UV Spectra= lambda _{max} = 260sh, 270, 290sh nm [[Reference:Murphy_RC:Pickett_WC:Culp_BR:Lands_WE:,Prostaglandins,1981,22,613|{{RelationTable/GetFirstAuthor|Reference:Murphy_RC:Pickett_WC:Culp_BR:Lands_WE:,Prostaglandins,1981,22,613}}]]<br /> |NMR Spectra=METHYL ESTER DIACETATE ; ^1 H-NMR(BENZEN-d_6 , 270MHz) : 6.79(dd, J=11.53, 14.83Hz, 1H, 8-CH), 6.34(dd, J=10.55, 14.83Hz, 1H, 10-CH), 6.09(dd, J=10.87, 14.83Hz, 1H, H-9), 6.03(t, J=11.53Hz, 7-CH), 5.90(dt, J =Ca.9.5, 11Hz, 5-CH), 5.63(dd, J=6.92, 14.82Hz, 11-CH), 5.60-5.38(m, 5H, 12,14,15,17,18-CH), 5.33(t, J=10.22Hz, 6-CH), 3.35(s, 3H), 2.83(m, 2H, 16-CH), 2.47(m, 1H, 13-CH), 2.38(m, 1H, 13-CH), 1.74(s, 3H), 1.68(s, 3H), 0.95(t, J=7.5Hz, 3H, 20-CH) [[Reference:Corey_EJ:Pyne_SG:Su_W:,Tetrah. Lett.,1983,24,4883|{{RelationTable/GetFirstAuthor|Reference:Corey_EJ:Pyne_SG:Su_W:,Tetrah. Lett.,1983,24,4883}}]]<br /> |Source=Leukotriene B5 is hardly detectable in human neutrophils, but is produced in the subjects fed with 5,8,11,14,17-eicosapentaenoic acid [[Reference:Prescott_SM:Zimmerman_GA:Morrison_AR:,Prostaglandins,1985,30,209|{{RelationTable/GetFirstAuthor|Reference:Prescott_SM:Zimmerman_GA:Morrison_AR:,Prostaglandins,1985,30,209}}]].<br /> |Chemical Synthesis=[[Reference:Corey_EJ:Pyne_SG:Su_W:,Tetrah. Lett.,1983,24,4883|{{RelationTable/GetFirstAuthor|Reference:Corey_EJ:Pyne_SG:Su_W:,Tetrah. Lett.,1983,24,4883}}]] {{Image200|LBF20503SF01FT0001.gif}}<br /> |Metabolism=Leukotriene B5 is produced via leukotriene A5 from 5,8,11,14,17-eicosapentaenoic acid, which is almost as active as arachidonic acid as substrate [[Reference:Yamamoto_S:,Biochim. Biophys. Acta,1992,1128,117|{{RelationTable/GetFirstAuthor|Reference:Yamamoto_S:,Biochim. Biophys. Acta,1992,1128,117}}]].<br /> |Symbol=LTB5<br /> |Biological Activity=Leukotriene B5 is about 1/30 as active as leukotriene B4 in stimulating aggregation of rat neutrophils, migration and lysosomal enzyme release of human polymorphonuclear leukocytes, and bradykinin-induced vascular permeability [[Reference:Terano_T:Salmon_JA:Moncada_S:,Prostaglandins,1984,27,217|{{RelationTable/GetFirstAuthor|Reference:Terano_T:Salmon_JA:Moncada_S:,Prostaglandins,1984,27,217}}]]. Leukotriene B5 is much less active than B4 to increase intracellular calciuim level in human neutrophils [[Reference:Seya_A:Terano_T:Tamura_Y:Yoshida_S:,Prostaglandins Leukot. Essent. Fatty Acids,1988,34,47|{{RelationTable/GetFirstAuthor|Reference:Seya_A:Terano_T:Tamura_Y:Yoshida_S:,Prostaglandins Leukot. Essent. Fatty Acids,1988,34,47}}]].<br /> }}<br /> <br /> {{Lipid/Footer}}</div>

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