https://lipidbank.jp/mediawiki/index.php?action=history&feed=atom&title=LBF22408AM04 2026-04-30T21:48:54Z Revision history for this page on the wiki MediaWiki 1.43.0 https://lipidbank.jp/mediawiki/index.php?title=LBF22408AM04&diff=56786&oldid=prev 2010-10-22T07:18:06Z

<p>New page: {{Lipid/Header}} {{Hierarchy|{{PAGENAME}}}} {{Metabolite |LipidBank=XPR7059 |LipidMaps=LMFA08020045 |SysName=N- (2-Methoxy-ethyl) -16,16-dimethyl- (cis-5,cis-8,cis-11,cis-14) -docosatetr...</p> <p><b>New page</b></p><div>{{Lipid/Header}}<br /> <br /> {{Hierarchy|{{PAGENAME}}}}<br /> <br /> {{Metabolite<br /> |LipidBank=XPR7059<br /> |LipidMaps=LMFA08020045<br /> |SysName=N- (2-Methoxy-ethyl) -16,16-dimethyl- (cis-5,cis-8,cis-11,cis-14) -docosatetraenoylamine<br /> |Common Name=&amp;&amp;N- (2-Methoxy-ethyl) -16,16-dimethyl- (5Z,8Z,11Z,14Z) -docosatetraenoylamine&amp;&amp;16,16-Dimethyldocosa- (5Z,8Z,11Z,14Z) -tetraenoyl-2&#039;-methoxyethylamine&amp;&amp;<br /> |NMR Spectra=^1 H NMR (CDCl3) delta 5.79 (br s, 1H, NH), 5.38 (m, 6H, 5,6,8,9,11,12-vinyl-H), 5.21 (m, 2H, 14,15-vinyl-H), 3.44,3.43 (s &amp; d overlapped, 4H, O-CH2-CH2-N), 3.36 (s, 3H, OCH3), 2.92 (t, 2H, J=6.0Hz, 13-CH2), 2.80 (m, 4H, 7,10-CH2), 2.18 (t, 2H, J=7.7Hz, 2-CH2), 2.12(m, 2H, 4-CH2), 1.71 (p, 2H, J=7.7Hz, 3-CH2), 1.25 (m, 10H, 17-21-CH2), 1.08 (s, 6H, gem-Me2), 0.86 (m, 3H, 22-CH2) [[Reference:Seltzman_HH:Fleming_DN:Thomas_BF:Gilliam_AF:McCallion_DS:Pertwee_RG:Compton_DR:Martin_BR:,J. Med. Chem.,1997,40,3626|{{RelationTable/GetFirstAuthor|Reference:Seltzman_HH:Fleming_DN:Thomas_BF:Gilliam_AF:McCallion_DS:Pertwee_RG:Compton_DR:Martin_BR:,J. Med. Chem.,1997,40,3626}}]]<br /> |Source=<br /> |Chemical Synthesis=A methanol solution of the corresponding ester, NaCN and 2-methoxyethylamine heated 2-days in a hot block at 50°C.Yield 4l %. [[Reference:Seltzman_HH:Fleming_DN:Thomas_BF:Gilliam_AF:McCallion_DS:Pertwee_RG:Compton_DR:Martin_BR:,J. Med. Chem.,1997,40,3626|{{RelationTable/GetFirstAuthor|Reference:Seltzman_HH:Fleming_DN:Thomas_BF:Gilliam_AF:McCallion_DS:Pertwee_RG:Compton_DR:Martin_BR:,J. Med. Chem.,1997,40,3626}}]]<br /> |Metabolism=<br /> |Biological Activity={{Image200|LBF20408AM04FT7059.gif}} [[Reference:Seltzman_HH:Fleming_DN:Thomas_BF:Gilliam_AF:McCallion_DS:Pertwee_RG:Compton_DR:Martin_BR:,J. Med. Chem.,1997,40,3626|{{RelationTable/GetFirstAuthor|Reference:Seltzman_HH:Fleming_DN:Thomas_BF:Gilliam_AF:McCallion_DS:Pertwee_RG:Compton_DR:Martin_BR:,J. Med. Chem.,1997,40,3626}}]]<br /> }}<br /> <br /> {{Lipid/Footer}}</div>

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