LBF20406HO13
| LipidBank Top (トップ) |
Fatty acid (脂肪酸) |
Glycerolipid (グリセロ脂質) |
Sphingolipid (スフィンゴ脂質) |
Journals (雑誌一覧) |
How to edit (ページの書き方) |
| IDs and Links | |
|---|---|
| LipidBank | DFA8131 |
| LipidMaps | LMFA03060006 |
| CAS | |
| KEGG | {{{KEGG}}} |
| KNApSAcK | {{{KNApSAcK}}} |
| mol | LBF20406HO13 |
| 8S-Hydroxy- (5Z,9E,11Z,14Z) -eicosatetraenoic acid | |
|---|---|
| |
| Structural Information | |
| 8S-Hydroxy- (cis-5,trans-9,cis-11,cis-14) -eicosatetraenoic acid | |
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| 8(S)-HETE | |
| Formula | C20H32O3 |
| Exact Mass | 320.23514489 |
| Average Mass | 320.46628 |
| SMILES | C(CC=CCC=CC=C[C@H](CC=CCCCC(O)=O)O)CCC |
| Physicochemical Information | |
| 8(S)-HETE is a major lipoxygenase product in PMA-treated mouse epidermis Hughes_MA et al.. | |
| 8(S)-HETE is synthesized from arachidonic acid by a 8(S)-lipoxygenase present in phorbol ester-treated mouse skin Hughes_MA et al.. | |
| Both 8(S)- and 8(R)-HETEs activate mouse skin protein kinase C at a dose of 100 μ M Hughes_MA et al.. It activates mouse keratinocyte protein kinase C with an IC_{50} of 100 mu M Lo_HH et al.. 8(S)-HETE also activates PPAR α selectively at concentrations as low as 0.3 μ M Yu_K et al.. | |
| Spectral Information | |
| Mass Spectra | |
| UV Spectra | λ max: 237nm ε : 27,000 |
| IR Spectra | |
| NMR Spectra | |
| Other Spectra | |
| Chromatograms | |
| Reported Metabolites, References | ||||||||||||||||||||
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