LBF20406HO13

Revision as of 07:26, 21 October 2010 by Editor (talk | contribs)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
LipidBank Top
(トップ)
Fatty acid
(脂肪酸)
Glycerolipid
(グリセロ脂質)
Sphingolipid
(スフィンゴ脂質)
Journals
(雑誌一覧)
How to edit
(ページの書き方)


Upper classes: LB LBF



8S-Hydroxy- (5Z,9E,11Z,14Z) -eicosatetraenoic acid
LBF20406HO13.png
Structural Information
8S-Hydroxy- (cis-5,trans-9,cis-11,cis-14) -eicosatetraenoic acid
  • 8S-Hydroxy- (5Z,9E,11Z,14Z) -eicosatetraenoic acid
8(S)-HETE
Formula C20H32O3
Exact Mass 320.23514489
Average Mass 320.46628
SMILES C(CC=CCC=CC=C[C@H](CC=CCCCC(O)=O)O)CCC
Physicochemical Information
8(S)-HETE is a major lipoxygenase product in PMA-treated mouse epidermis Hughes_MA et al..
8(S)-HETE is synthesized from arachidonic acid by a 8(S)-lipoxygenase present in phorbol ester-treated mouse skin Hughes_MA et al..
Both 8(S)- and 8(R)-HETEs activate mouse skin protein kinase C at a dose of 100 μ M Hughes_MA et al.. It activates mouse keratinocyte protein kinase C with an IC_{50} of 100 mu M Lo_HH et al.. 8(S)-HETE also activates PPAR α selectively at concentrations as low as 0.3 μ M Yu_K et al..
Spectral Information
Mass Spectra
UV Spectra λ max: 237nm ε : 27,000
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20406HO13 See above. Hughes_MA et al. 1991
n.a. LBF20406HO13 See above. Lo_HH et al. 1994
n.a. LBF20406HO13 See above. Yu_K et al. 1995