Category:LBS
Sphingolipid
Class Overview
Sphingosine & Ceramide
Sphingosine is synthesized from decarboxylating condensation of palmitoyl CoA with serine. It is a 18-carbon amino alcohol (16 carbons from palmitic acid and 2 from serine) with one unsaturated bond (2-amino-4-octadecene-1,3-diol). Sphingosine is further acylated to form ceramide, an important component of cell membranes.
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スフィンゴシンはパルミトイルCoAがアミノ酸セリンと脱炭酸縮合して生成します。炭素を18個含むアミノアルコール(16個がパルミチン酸、2個がセリン由来)で不飽和結合を1つ含んでいます (2-amino-4-octadecene-1,3-diol)。
スフィンゴシンがアシル化したものが、細胞膜の重要な成分であるセラミドです。
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Abbreviations
Template:BilingualID番号 (ページタイトル) の設計
L | B | S | x | s1 | s2 | s3 | n1 | n2 | y | c1 | c2 |
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Sugar Code
code | sugar | code | sugar | code | sugar |
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0 | no sugar | A | other Galactose (Gal) including methylation |
L | sialic acids (NeuAc, NeuGc, KDN) |
1 | Galα1-3 | B | GlcNAcβ1-3 | M | 'Glucuronic acid (GlcA) |
2 | Galα1-4 | C | GlcNAcβ1-4 | N | Pentose sugars (Ara, Xyl) and rhamnose (Rha) |
3 | Galα1-6 | D | GlcNAcβ1-6 | P | phosphocholine (PC), phosphate (HPO3), sulphate (HSO3), and ethylene (2C=CH) |
4 | Galβ1-3 | E | Other N-acetyl galactosamine (GalNAc) and N-acetyl glucosamine (GlcNAc) |
Q | Aminoethylphosphate (AEPn, MAEPr, EtnP) |
5 | Galβ1-4 | F | Galactosamine (GalN) and Glucosamine (GlcN) |
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6 | Galβ1-6 | G | Other Glucose (Glc) | ||
7 | GalNAcβ1-3 | H | Mannose (Man) | ||
8 | GalNAcβ1-4 | J | Inositol (Ins) | ||
9 | GalNAcβ1-6 | K | Fucose (Fuc) |
Classification
By the Number of Sugars 糖の個数
For glycosphingolipid, 2 digits following LBS stand for the number of attached sugars. For phosphosphingolipid, the code of phosphorylation, PP. |
スフィンゴ糖脂質は結合している糖の総数をLBSに続く2桁の数字で、スフィンゴリン脂質は数字の代わりにリン酸化修飾を示す記号PPで分類しています。 |
Sphingolipid Overview | ||
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Polysaccharide Chain
Glycosphingolipids (Abbr. R = Galβ1-4Glcβ1-Cer) | |||||||||||||||||
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Ganglio [Gg] (??) GalNAcβ1-4R |
Lacto [Lc] (??) GlcNAcβ1-3R |
Globo [Gb] (??) Galα1-4R |
Root [R] (??) derivatives of R | ||||||||||||||
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Isoganglio [IG] (??) GalNAcβ1-3R |
Lacto with β1-6 [L6] (??) GlcNAcβ1-6R |
Isoglobo [IB] (??) Galα1-3R | |||||||||||||||
Lactoganglio [LG]
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Isogloboganglio [BG]
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Glycosphingolipids without ROOT | ||||||||||||
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Glc-Cer (??) Glcβ1-Cer |
Gal-Cer (??) Galβ1-Cer | |||||||||||
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Phospho (??) Ino-P-Cer |
Others (??) | |||||||||||
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