LBF16306HO01: Difference between revisions

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|LipidBank=DFA8137
|LipidBank=DFA8137
|LipidMaps=LMFA01050143
|LipidMaps=LMFA01050143
|SysName=8R-hydroxy-4Z,6E,10Z-hexadecatrienoic acid
|SysName=8R-Hydroxy- (cis-4,trans-6,cis-10) -hexadecatrienoic acid
|Common Name=&&8R-hydroxy-4Z,6E,10Z-hexadecatrienoic acid&&
|Common Name=&&8-(R)-Hydroxy- (4Z,6E,10Z) -hexadecatrienoic acid&&8R-Hydroxy- (4Z,6E,10Z) -hexadecatrienoic acid&&
|UV Spectra=<FONT FACE="Symbol">l</FONT>max: 234nm <FONT FACE="Symbol">e</FONT>: 23,000
|UV Spectra= lambda max: 234nm epsilon : 23,000
|Source=
|Source=
|Chemical Synthesis=
|Chemical Synthesis=
|Metabolism=Metabolism of 12(R)-HETE in corneal tissue produces predominantly the compound resulting from the loss of four carbon atoms through <FONT FACE="Symbol">b</FONT>-oxidation from C-1 [[Reference:Nishimura_M:Schwartzman_ML:Falck_JR:Lumin_S:Zirrolli_JA:Murphy_RC:,Arch. Biochem. Biophys.,1991,290,326|{{RelationTable/GetFirstAuthor|Reference:Nishimura_M:Schwartzman_ML:Falck_JR:Lumin_S:Zirrolli_JA:Murphy_RC:,Arch. Biochem. Biophys.,1991,290,326}}]];>. This metabolite is 8(R)-hydroxy hexadecatrienoic acid (8(R)-HHxTrE) or 2,3,4,5-tetranor 12(R)-HETE.
|Metabolism=Metabolism of 12(R)-HETE in corneal tissue produces predominantly the compound resulting from the loss of four carbon atoms through beta -oxidation from C-1 [[Reference:Nishimura_M:Schwartzman_ML:Falck_JR:Lumin_S:Zirrolli_JA:Murphy_RC:,Arch. Biochem. Biophys.,1991,290,326|{{RelationTable/GetFirstAuthor|Reference:Nishimura_M:Schwartzman_ML:Falck_JR:Lumin_S:Zirrolli_JA:Murphy_RC:,Arch. Biochem. Biophys.,1991,290,326}}]]. This metabolite is 8(R)-hydroxy hexadecatrienoic acid (8(R)-HHxTrE) or 2,3,4,5-tetranor 12(R)-HETE.
|Symbol=8(R)-HHxTrE/2,3,4,5-tetranor 12(R)-HETE
}}
}}


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{{Lipid/Footer}}

Latest revision as of 06:23, 21 October 2010

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Upper classes: LB LBF



8-(R)-Hydroxy- (4Z,6E,10Z) -hexadecatrienoic acid
LBF16306HO01.png
Structural Information
8R-Hydroxy- (cis-4,trans-6,cis-10) -hexadecatrienoic acid
  • 8-(R)-Hydroxy- (4Z,6E,10Z) -hexadecatrienoic acid
  • 8R-Hydroxy- (4Z,6E,10Z) -hexadecatrienoic acid
8(R)-HHxTrE/2,3,4,5-tetranor 12(R)-HETE
Formula C16H26O3
Exact Mass 266.18819469799996
Average Mass 266.37584
SMILES CCCCCC=CCC(O)C=CC=CCCC(O)=O
Physicochemical Information
Metabolism of 12(R)-HETE in corneal tissue produces predominantly the compound resulting from the loss of four carbon atoms through beta -oxidation from C-1 Nishimura_M et al.. This metabolite is 8(R)-hydroxy hexadecatrienoic acid (8(R)-HHxTrE) or 2,3,4,5-tetranor 12(R)-HETE.
Spectral Information
Mass Spectra
UV Spectra λ max: 234nm ε : 23,000
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF16306HO01 See above. Nishimura_M et al. 1991