LBF20107PG04: Difference between revisions

Latest revision as of 08:01, 21 October 2010

Upper classes: LB LBF

15-keto Prostaglandin E₁

Structural Information
	9,15-Dioxo-11α-hydroxy-prost-trans-13-en-1-oic acid
	15-keto Prostaglandin E₁ 9,15-Dioxo-11α-hydroxy-prost-13(E)-en-1-oic acid

Formula	C20H32O5
Exact Mass	352.224974134
Average Mass	352.46508
SMILES	`C(CCC(=O)C=C[C@H]([C@H]1CCCCCCC(O)=O)[C@@H](CC1=O)O)CC`
Physicochemical Information






	15-keto PGE1 is the inactive metabolite of PGE1 via PG15-dehydrogenase


	15-keto PGE1 has very slight biological activity compared to PGE1. Westwick_J


Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra
Other Spectra
Chromatograms

Reported Metabolites, References

Biospecies	ID	Compound Name	Reference	Comment
n.a.	LBF20107PG04	See above.	Westwick_J 1976

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+{{Lipid/Header}}
 {{Hierarchy|{{PAGENAME}}}}
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 |LipidBank=XPR1709
 |LipidMaps=LMFA03010146
-|SysName=9,15-dioxo-11alpha-hydroxy-prost-13E-en-1-oic acid
+|SysName=9,15-Dioxo-11alpha-hydroxy-prost-trans-13-en-1-oic acid
-|Common Name=&&15-keto Prostaglandin E_1&&9,15-dioxo-11alpha-hydroxy-prost-13E-en-1-oic acid&&
+|Common Name=&&15-keto Prostaglandin E_1&&9,15-Dioxo-11alpha-hydroxy-prost-13(E)-en-1-oic acid&&
+|Source=15-keto PGE1 is the inactive metabolite of PGE1 via PG15-dehydrogenase
+|Chemical Synthesis=
+|Metabolism=
+|Biological Activity=15-keto PGE1 has very slight biological activity compared to PGE1.[[Reference:Westwick_J:,Br. J. Pharmacol.,1976,58,297P|{{RelationTable/GetFirstAuthor|Reference:Westwick_J:,Br. J. Pharmacol.,1976,58,297P}}]]
 }}
+{{Lipid/Footer}}