LBF20107PG10: Difference between revisions

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|LipidBank=XPR1736
|LipidBank=XPR1736
|LipidMaps=LMFA03010054
|LipidMaps=LMFA03010054
|SysName=9-oxo-15S-hydroxy-prosto-13E-en-1-oic acid
|SysName=9-Oxo-15S-hydroxy-prosto-trans-13-en-1-oic acid
|Common Name=&&11-deoxy Prostaglandin E_1&&9-oxo-15S-hydroxy-prosto-13E-en-1-oic acid&&
|Common Name=&&11-deoxy Prostaglandin E_1&&9-Oxo-15S-hydroxy-prosto-13(E)-en-1-oic acid&&
|Source=
|Source=
|Chemical Synthesis=
|Chemical Synthesis=

Latest revision as of 08:07, 21 October 2010

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Upper classes: LB LBF



11-deoxy Prostaglandin E1
LBF20107PG10.png
Structural Information
9-Oxo-15S-hydroxy-prosto-trans-13-en-1-oic acid
  • 11-deoxy Prostaglandin E1
  • 9-Oxo-15S-hydroxy-prosto-13(E)-en-1-oic acid
Formula C20H34O4
Exact Mass 338.24570957599997
Average Mass 338.48156
SMILES C(CC[C@@H](O)C=C[C@H]([C@H]1CCCCCCC(O)=O)CCC(=O)1)CC
Physicochemical Information
11-deoxy Prostaglandin E1 shows spieces and subtype dependent EP agonistic effect. In guinea pig, 11-deoxy Prostaglandin E1 induce bronchodilation and vasodepression. Hall_DW et al. 11-deoxy Prostaglandin E1 is reported to increase cAMP release via EP receptors in Jurkat cells. De_Vries_GW et al. The Ki value of each murine EPs is 600 nM (EP1), 45 nM (EP2), 1.1 nM (EP3), 23 nM (EP4) . Kiriyama_M et al. 11-deoxy Prostaglandin E1, a selective EP2/EP3/EP4 agonist, inhibites IL-1beta-induced IL-6 production in human gingival fibroblast. Noguchi_K et al. 11-deoxy Prostaglandin E1 stimulates K secretion through EP2 receptors at EC50 values of 8.3 nM in guinea pig distal colonic mucosa . Halm_DR et al.
Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20107PG10 See above. De_Vries_GW et al. 1995
n.a. LBF20107PG10 See above. Hall_DW et al. 1976
n.a. LBF20107PG10 See above. Halm_DR et al. 2001
n.a. LBF20107PG10 See above. Kiriyama_M et al. 1997
n.a. LBF20107PG10 See above. Noguchi_K et al. 2002