LBF20303PG06: Difference between revisions

Latest revision as of 09:00, 21 October 2010

Upper classes: LB LBF

Prostaglandin I₃

Structural Information
	(6,9α) -Epoxy- (11α,15S) -dihydroxy-prosta- (cis-5,trans-13,cis-17) -trien-1-oic acid
	Prostaglandin I₃ (6,9α) -Epoxy- (11α,15S) -dihydroxy-prosta- (5Z,13E,17Z) -trien-1-oic acid

Formula	C20H30O5
Exact Mass	350.20932407
Average Mass	350.4492
SMILES	`C(=CC[C@@H](O)C=C[C@H]([C@H]12)[C@H](O)C[C@H](O[C@@H](C2)C=CCCC(O)=O)1)CC`
Physicochemical Information






	PGI3 is synthesized from EPA by cyclooxygenase and PGI synthase.


	PGI3 has equal ability to PGI2 in inhibitting human platelet aggregation. Mann_NJ et al.


Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra
Other Spectra
Chromatograms

Reported Metabolites, References

Biospecies	ID	Compound Name	Reference	Comment
n.a.	LBF20303PG06	See above.	Mann_NJ et al. 1994

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+{{Lipid/Header}}
 {{Hierarchy|{{PAGENAME}}}}
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 |LipidBank=XPR1725
 |LipidMaps=LMFA03010045
-|SysName=6,9alpha-epoxy-11alpha,15S-dihydroxy-prosta-5Z,13E,17Z-trien-1-oic acid
+|SysName=(6,9alpha) -Epoxy- (11alpha,15S) -dihydroxy-prosta- (cis-5,trans-13,cis-17) -trien-1-oic acid
-|Common Name=&&Prostaglandin I3&&
+|Common Name=&&Prostaglandin I_3&&(6,9alpha) -Epoxy- (11alpha,15S) -dihydroxy-prosta- (5Z,13E,17Z) -trien-1-oic acid&&
+|Source=PGI3 is synthesized from EPA by cyclooxygenase and PGI synthase.
+|Chemical Synthesis=
+|Metabolism=
+|Biological Activity=PGI3 has equal ability to PGI2 in inhibitting human platelet aggregation.[[Reference:Mann_NJ:Warrick_GE:ODea_K:Knapp_HR:Sinclair_AJ:,Lipids,1994,29,157|{{RelationTable/GetFirstAuthor|Reference:Mann_NJ:Warrick_GE:ODea_K:Knapp_HR:Sinclair_AJ:,Lipids,1994,29,157}}]]
 }}
+{{Lipid/Footer}}