LBF20303PG07: Difference between revisions

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|LipidBank=XPR1797
|LipidBank=XPR1797
|LipidMaps=-
|LipidMaps=-
|SysName=9a,11a,15S-trihydroxy- (8b) -prosta-5Z,13E,17Z-trien-1-oic acid
|SysName=(9alpha,11alpha,15S) -Trihydroxy- (8b) -prosta- (cis-5,trans-13,cis-17) -trien-1-oic acid
|Common Name=&&8-iso Prostaglandin F_3alpha&&9a,11a,15S-trihydroxy- (8b) -prosta-5Z,13E,17Z-trien-1-oic acid&&
|Common Name=&&8-iso Prostaglandin F_3 alpha&&(9alpha,11alpha,15S) -Trihydroxy- (8b) -prosta- (5Z,13E,17Z) -trien-1-oic acid&&
|Source=
|Chemical Synthesis=
|Metabolism=
|Biological Activity=There is only one report on 8-iso PGF3 alpha  showing inactive in a TP receptor mediated assay of human platelet shape change, where 8-iso PGF2 alpha  has an ED50 value of 1  mu M.[[Reference:Pratico_D:Smyth_EM:Violi_F:FitzGerald_GA:,J. Biol. Chem.,1996,271,14916|{{RelationTable/GetFirstAuthor|Reference:Pratico_D:Smyth_EM:Violi_F:FitzGerald_GA:,J. Biol. Chem.,1996,271,14916}}]]
}}
}}


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{{Lipid/Footer}}

Latest revision as of 09:00, 21 October 2010

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Upper classes: LB LBF



8-iso Prostaglandin F3α
LBF20303PG07.png
Structural Information
(9α,11α,15S) -Trihydroxy- (8b) -prosta- (cis-5,trans-13,cis-17) -trien-1-oic acid
  • 8-iso Prostaglandin F3α
  • (9α,11α,15S) -Trihydroxy- (8b) -prosta- (5Z,13E,17Z) -trien-1-oic acid
Formula C20H32O5
Exact Mass 352.224974134
Average Mass 352.46508
SMILES C(=CC[C@H](O)C=C[C@H]([C@@H]1CC=CCCCC(O)=O)[C@@H](C[C@@H]1O)O)CC
Physicochemical Information
There is only one report on 8-iso PGF3 alpha showing inactive in a TP receptor mediated assay of human platelet shape change, where 8-iso PGF2 alpha has an ED50 value of 1 mu M. Pratico_D et al.
Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20303PG07 See above. Pratico_D et al. 1996