LBF20306EO02: Difference between revisions

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|LipidBank=DFA8111
|LipidBank=DFA8111
|LipidMaps=-
|LipidMaps=-
|SysName= dl-8 (9) -Epoxy-5Z,11Z,14Z-eicosatrienoic acid
|SysName= dl-8 (9) -Epoxy- (5-cis,11-cis,14-cis) -icosatrienoic acid
|Common Name=&&(+-) -8 (9) -Epoxy-5Z,11Z,14Z-eicosatrienoic acid&&
|Common Name=&&(+-) -8 (9) -Epoxy- (5Z,11Z,14Z) -eicosatrienoic acid&&
|Source=(±)8(9)-EpETrE is biosynthesized in rat and rabbit liver microsomes by cytochrome P450 [[Reference:Oliw_EH:Guengerich_FP:Oates_JA:,J. Biol. Chem.,1982,257,3771|{{RelationTable/GetFirstAuthor|Reference:Oliw_EH:Guengerich_FP:Oates_JA:,J. Biol. Chem.,1982,257,3771}}]][[Reference:Chacos_N:Falck_JR:Wixtrom_C:Capdevila_J:,Biochem. Biophys. Res. Commun.,1982,104,916|{{RelationTable/GetFirstAuthor|Reference:Chacos_N:Falck_JR:Wixtrom_C:Capdevila_J:,Biochem. Biophys. Res. Commun.,1982,104,916}}]]. (±)8(9)-EpETrE is a major P450 metabolite in the renal cortex [[Reference:Zhang_JY:Prakash_C:Yamashita_K:Blair_IA:,Biochem. Biophys. Res. Commun.,1992,183,138|{{RelationTable/GetFirstAuthor|Reference:Zhang_JY:Prakash_C:Yamashita_K:Blair_IA:,Biochem. Biophys. Res. Commun.,1992,183,138}}]].
|Source=(±)8(9)-EpETrE is biosynthesized in rat and rabbit liver microsomes by cytochrome P450 [[Reference:Oliw_EH:Guengerich_FP:Oates_JA:,J. Biol. Chem.,1982,257,3771|{{RelationTable/GetFirstAuthor|Reference:Oliw_EH:Guengerich_FP:Oates_JA:,J. Biol. Chem.,1982,257,3771}}]][[Reference:Chacos_N:Falck_JR:Wixtrom_C:Capdevila_J:,Biochem. Biophys. Res. Commun.,1982,104,916|{{RelationTable/GetFirstAuthor|Reference:Chacos_N:Falck_JR:Wixtrom_C:Capdevila_J:,Biochem. Biophys. Res. Commun.,1982,104,916}}]]. (±)8(9)-EpETrE is a major P450 metabolite in the renal cortex [[Reference:Zhang_JY:Prakash_C:Yamashita_K:Blair_IA:,Biochem. Biophys. Res. Commun.,1992,183,138|{{RelationTable/GetFirstAuthor|Reference:Zhang_JY:Prakash_C:Yamashita_K:Blair_IA:,Biochem. Biophys. Res. Commun.,1992,183,138}}]].
|Chemical Synthesis=
|Chemical Synthesis=

Revision as of 04:48, 28 May 2010

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Upper classes: LB LBF



(+-) -8 (9) -Epoxy- (5Z,11Z,14Z) -eicosatrienoic acid
LBF20306EO02.png
Structural Information
dl-8 (9) -Epoxy- (5-cis,11-cis,14-cis) -icosatrienoic acid
  • (+-) -8 (9) -Epoxy- (5Z,11Z,14Z) -eicosatrienoic acid
(+-)8(9)-EpETrE
Formula C20H32O3
Exact Mass 320.23514489
Average Mass 320.46628
SMILES C(CC=CCC=CCC(O1)C1CC=CCCCC(O)=O)CCC
Physicochemical Information
(±)8(9)-EpETrE is biosynthesized in rat and rabbit liver microsomes by cytochrome P450 Oliw_EH et al. Chacos_N et al.. (±)8(9)-EpETrE is a major P450 metabolite in the renal cortex Zhang_JY et al..
(±)8(9)-EpETrE reduces the glomerular filtration rate (GFR) through cyclooxygenase-dependent preglomerular vasoconstriction Katoh_T et al.>.(±)8(9)-EpETrE has been shown to play a role in the recovery of depleted Ca^{2+} pools in cultured smooth muscle cells Graber_MN et al..
Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20306EO02 See above. Chacos_N et al. 1982
n.a. LBF20306EO02 See above. Graber_MN et al. 1997
n.a. LBF20306EO02 See above. Katoh_T et al. 1991
n.a. LBF20306EO02 See above. Oliw_EH et al. 1982
n.a. LBF20306EO02 See above. Zhang_JY et al. 1992