LBF20306HO01: Difference between revisions

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|LipidBank=DFA8106
|LipidBank=DFA8106
|LipidMaps=LMFA03050004
|LipidMaps=LMFA03050004
|SysName= (+-) 5, 6-dihydroxy-8Z,11Z,14Z-eicosatrienoic acid
|SysName=dl-5, 6-Dihydroxy- (cis-8,cis-11,cis-14) -eicosatrienoic acid
|Common Name=&&(+-) 5, 6-dihydroxy-8Z,11Z,14Z-eicosatrienoic acid&&
|Common Name=&&(+-) -5, 6-Dihydroxy- (8Z,11Z,14Z) -eicosatrienoic acid&&
|Source=
|Source=
|Chemical Synthesis=
|Chemical Synthesis=
|Metabolism=Epoxide hydrolases convert the EpETrEs into vicinal diols[[Reference:Oliw_EH:Guengerich_FP:Oates_JA:,J. Biol. Chem.,1982,257,3771|{{RelationTable/GetFirstAuthor|Reference:Oliw_EH:Guengerich_FP:Oates_JA:,J. Biol. Chem.,1982,257,3771}}]], with the concurrent loss of much of their biological activity. (±)5,6-DiHETrE is a substrate for sheep seminal vesicle cyclooxygenase, producing 5,6-dihydroxy PGE1 and F1 metabolites in vitro[[Reference:Oliw_EH:,Biochim. Biophys. Acta,1984,795,384|{{RelationTable/GetFirstAuthor|Reference:Oliw_EH:,Biochim. Biophys. Acta,1984,795,384}}]].
|Metabolism=Epoxide hydrolases convert the EpETrEs into vicinal diols[[Reference:Oliw_EH:Guengerich_FP:Oates_JA:,J. Biol. Chem.,1982,257,3771|{{RelationTable/GetFirstAuthor|Reference:Oliw_EH:Guengerich_FP:Oates_JA:,J. Biol. Chem.,1982,257,3771}}]], with the concurrent loss of much of their biological activity. (±)5,6-DiHETrE is a substrate for sheep seminal vesicle cyclooxygenase, producing 5,6-dihydroxy PGE1 and F1 metabolites in vitro[[Reference:Oliw_EH:,Biochim. Biophys. Acta,1984,795,384|{{RelationTable/GetFirstAuthor|Reference:Oliw_EH:,Biochim. Biophys. Acta,1984,795,384}}]].
|Symbol=(±)5,6-DiHETrE
|Symbol=(+-)5,6-DiHETrE
}}
}}


{{Lipid/Footer}}
{{Lipid/Footer}}

Latest revision as of 07:19, 21 October 2010

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Upper classes: LB LBF



(+-) -5, 6-Dihydroxy- (8Z,11Z,14Z) -eicosatrienoic acid
LBF20306HO01.png
Structural Information
dl-5, 6-Dihydroxy- (cis-8,cis-11,cis-14) -eicosatrienoic acid
  • (+-) -5, 6-Dihydroxy- (8Z,11Z,14Z) -eicosatrienoic acid
(+-)5,6-DiHETrE
Formula C20H34O4
Exact Mass 338.24570957599997
Average Mass 338.48156
SMILES C(CC=CCC=CCC=CCC(O)C(O)CCCC(O)=O)CCC
Physicochemical Information
Epoxide hydrolases convert the EpETrEs into vicinal diols Oliw_EH et al., with the concurrent loss of much of their biological activity. (±)5,6-DiHETrE is a substrate for sheep seminal vesicle cyclooxygenase, producing 5,6-dihydroxy PGE1 and F1 metabolites in vitro Oliw_EH .
Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20306HO01 See above. Oliw_EH 1984
n.a. LBF20306HO01 See above. Oliw_EH et al. 1982