LBF20306HO02: Difference between revisions
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|Chemical Synthesis= | |Chemical Synthesis= | ||
|Metabolism= | |Metabolism= | ||
|Symbol=(±)8,9-DiHETrE | |||
|Biological Activity=Epoxide hydrolases convert the EpETrEs into vicinal diols[[Reference:Oliw_EH:Guengerich_FP:Oates_JA:,J. Biol. Chem.,1982,257,3771|{{RelationTable/GetFirstAuthor|Reference:Oliw_EH:Guengerich_FP:Oates_JA:,J. Biol. Chem.,1982,257,3771}}]], with the concurrent loss of much of their biological activity. The 8(S),9(R)-EpETrE isomer is metabolized by platelet cyclooxygenase to form 8(S),9(R)-THETA, a trihydroxy fatty acid which may act as a renal vasoconstrictor[[Reference:Zhang_JY:Prakash_C:Yamashita_K:Blair_IA:,Biochem. Biophys. Res. Commun.,1992,183,138|{{RelationTable/GetFirstAuthor|Reference:Zhang_JY:Prakash_C:Yamashita_K:Blair_IA:,Biochem. Biophys. Res. Commun.,1992,183,138}}]]. | |||
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{{Lipid/Footer}} | {{Lipid/Footer}} | ||
Revision as of 21:00, 6 January 2010
| LipidBank Top (トップ) |
Fatty acid (脂肪酸) |
Glycerolipid (グリセロ脂質) |
Sphingolipid (スフィンゴ脂質) |
Journals (雑誌一覧) |
How to edit (ページの書き方) |
| IDs and Links | |
|---|---|
| LipidBank | DFA8107 |
| LipidMaps | LMFA03050006 |
| CAS | |
| KEGG | {{{KEGG}}} |
| KNApSAcK | {{{KNApSAcK}}} |
| mol | LBF20306HO02 |
| (+-) 8,9-dihydroxy-5Z,11Z,14Z-eicosatrienoic acid | |
|---|---|
| |
| Structural Information | |
| (+-) 8,9-dihydroxy-5Z,11Z,14Z-eicosatrienoic acid | |
| |
| (±)8,9-DiHETrE | |
| Formula | C20H34O4 |
| Exact Mass | 338.24570957599997 |
| Average Mass | 338.48156 |
| SMILES | C(CC=CCC=CCC(O)C(O)CC=CCCCC(O)=O)CCC |
| Physicochemical Information | |
| Epoxide hydrolases convert the EpETrEs into vicinal diols Oliw_EH et al., with the concurrent loss of much of their biological activity. The 8(S),9(R)-EpETrE isomer is metabolized by platelet cyclooxygenase to form 8(S),9(R)-THETA, a trihydroxy fatty acid which may act as a renal vasoconstrictor Zhang_JY et al.. | |
| Spectral Information | |
| Mass Spectra | |
| UV Spectra | |
| IR Spectra | |
| NMR Spectra | |
| Other Spectra | |
| Chromatograms | |
| Reported Metabolites, References | |||||||||||||||
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