LBF20307PG02: Difference between revisions
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|Common Name=&&19-HYDROXY-PROSTAGLANDIN A_2&&7- [ 2 (R) - (3 (S) ,7-Dihydroxy-1 (E) -octenyl) -5-oxo-3-cyclopenten-1 (R) -yl ] -5 (Z) -heptenoic acid&&15 (S) ,19-Dihydroxy-9-oxo-8 (12) ,13-trans-prostadienoic acid&& | |Common Name=&&19-HYDROXY-PROSTAGLANDIN A_2&&7- [ 2 (R) - (3 (S) ,7-Dihydroxy-1 (E) -octenyl) -5-oxo-3-cyclopenten-1 (R) -yl ] -5 (Z) -heptenoic acid&&15 (S) ,19-Dihydroxy-9-oxo-8 (12) ,13-trans-prostadienoic acid&& | ||
|Solubility=DIETHYL ETHER, CHLOROFORM, ETHANOL [[Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257|{{RelationTable/GetFirstAuthor|Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257}}]] | |Solubility=DIETHYL ETHER, CHLOROFORM, ETHANOL [[Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257|{{RelationTable/GetFirstAuthor|Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257}}]] | ||
|Mass Spectra=METHYL ESTER ; m/e 364(M | |Mass Spectra=METHYL ESTER ; m/e 364(M^+ ), 246, 328, 315 [[Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257|{{RelationTable/GetFirstAuthor|Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257}}]] | ||
|UV Spectra= | |UV Spectra=lambda ^E_m _a _x = 217 nm(epsilon ∼10,000) [[Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257|{{RelationTable/GetFirstAuthor|Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257}}]] | ||
|IR Spectra= 5.87, 6.30, 10. | |IR Spectra= 5.87, 6.30, 10.3mum [[Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257|{{RelationTable/GetFirstAuthor|Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257}}]] | ||
|NMR Spectra= | |NMR Spectra=^1 H-NMR : delta 5.75-5.50(m, 2H,13, 14-CH), 5.50-5.25(m, 2H, 5,6-CH), 1.15(d, 3H, 20-CH) [[Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257|{{RelationTable/GetFirstAuthor|Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257}}]] | ||
|Source=The compound is contained in human seminal plasma in a considerable amount [[Reference:Bergstrom_S:,Science,1967,157,382|{{RelationTable/GetFirstAuthor|Reference:Bergstrom_S:,Science,1967,157,382}}]], but it is attributed presumably to a degradation product of 19-hydroxy-prostagaldnin E2 [[Reference:Taylor_PL:Kelly_RW:,Nature,1974,250,665|{{RelationTable/GetFirstAuthor|Reference:Taylor_PL:Kelly_RW:,Nature,1974,250,665}}]]. | |Source=The compound is contained in human seminal plasma in a considerable amount [[Reference:Bergstrom_S:,Science,1967,157,382|{{RelationTable/GetFirstAuthor|Reference:Bergstrom_S:,Science,1967,157,382}}]], but it is attributed presumably to a degradation product of 19-hydroxy-prostagaldnin E2 [[Reference:Taylor_PL:Kelly_RW:,Nature,1974,250,665|{{RelationTable/GetFirstAuthor|Reference:Taylor_PL:Kelly_RW:,Nature,1974,250,665}}]]. | ||
|Chemical Synthesis= | |Chemical Synthesis= |
Revision as of 14:00, 19 February 2010
LipidBank Top (トップ) |
Fatty acid (脂肪酸) |
Glycerolipid (グリセロ脂質) |
Sphingolipid (スフィンゴ脂質) |
Journals (雑誌一覧) |
How to edit (ページの書き方) |
IDs and Links | |
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LipidBank | XPR1031 |
LipidMaps | LMFA03010130 |
CAS | |
KEGG | {{{KEGG}}} |
KNApSAcK | {{{KNApSAcK}}} |
mol | LBF20307PG02 |
19-HYDROXY-PROSTAGLANDIN A2 | |
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Structural Information | |
7- [ 2 (R) - (3 (S) ,7-Dihydroxy-1 (E) -octenyl) -5-oxo-3-cyclopenten-1 (R) -yl ] -5 (Z) -heptenoic acid / 15 (S) ,19-Dihydroxy-9-oxo-8 (12) ,13-trans-prostadienoic acid | |
| |
19-HYDROXY-PGA2 | |
Formula | C20H30O5 |
Exact Mass | 350.20932407 |
Average Mass | 350.4492 |
SMILES | O[C@H](CCC[C@H](C)O)C=C[C@H]([C@H]1CC=CCCCC(O)=O)C=CC(=O)1 |
Physicochemical Information | |
DIETHYL ETHER, CHLOROFORM, ETHANOL HambergMet al. | |
The compound is contained in human seminal plasma in a considerable amount Bergstrom_S , but it is attributed presumably to a degradation product of 19-hydroxy-prostagaldnin E2 Taylor_PL et al.. | |
19-Hydroxy-prostaglandin A2 relaxes uterine myometriuim Horton_EW . | |
Spectral Information | |
Mass Spectra | METHYL ESTER ; m/e 364(M+), 246, 328, 315 HambergMet al. |
UV Spectra | λ E m ax = 217 nm(ε ∼10,000) HambergMet al. |
IR Spectra | 5.87, 6.30, 10.3mum HambergMet al. |
NMR Spectra | 1H-NMR : δ 5.75-5.50(m, 2H,13, 14-CH), 5.50-5.25(m, 2H, 5,6-CH), 1.15(d, 3H, 20-CH) HambergMet al. |
Other Spectra | |
Chromatograms |
Reported Metabolites, References | |||||||||||||||||||||||||
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