LBF20307PG04: Difference between revisions

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{{Lipid/Header}}
{{Hierarchy|{{PAGENAME}}}}
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|LipidBank=XPR1131
|LipidBank=XPR1131
|LipidMaps=LMFA03010132
|LipidMaps=LMFA03010132
|SysName=7- [ 2- (3 (S) ,7-Dihydroxy-1 (E) -octenyl) -5-oxo-1-cyclopenten-1-yl ] -5 (Z) -heptenoic acid / 15 (S) ,19-Dihydroxy-9-oxo-5-cis-8 (12) ,13-trans-prostatrienoic acid
|SysName=7- [2R- ((3S,7)-Dihydroxy-trans-1-octenyl) -5-oxo-1-cyclopenten-1R-yl] -cis-5-heptenoic acid
|Common Name=&&19-HYDROXY-PROSTAGLANDIN B_2&&7- [ 2- (3 (S) ,7-Dihydroxy-1 (E) -octenyl) -5-oxo-1-cyclopenten-1-yl ] -5 (Z) -heptenoic acid&&15 (S) ,19-Dihydroxy-9-oxo-5-cis-8 (12) ,13-trans-prostatrienoic acid&&
|Common Name=&&19-hydroxy Prostaglandin B_2&&(15S,19)-Dihydroxy-9-oxo-5-cis-8(12),13-trans-prostadienoic acid&&7- [2R- ((3S,7)-Dihydroxy-1-(E)-octenyl) -5-oxo-1-cyclopenten-1R-yl] -5-(Z)-heptenoic acid
|Solubility=ETHANOL [[Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257|{{RelationTable/GetFirstAuthor|Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257}}]]
|Solubility=ETHANOL [[Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257|{{RelationTable/GetFirstAuthor|Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257}}]]
|UV Spectra=<FONT FACE="Symbol">l</FONT> <SUP><FONT SIZE=-1>E</FONT></SUP><SUP><FONT SIZE=-1>t</FONT></SUP><SUP><FONT SIZE=-1>O</FONT></SUP><SUP><FONT SIZE=-1>H</FONT></SUP><SUB><FONT SIZE=-1>m</FONT></SUB><SUB><FONT SIZE=-1>a</FONT></SUB><SUB><FONT SIZE=-1>x</FONT></SUB> = 278 nm(<FONT FACE="Symbol">e</FONT> ˜20,000) [[Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257|{{RelationTable/GetFirstAuthor|Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257}}]]
|UV Spectra= lambda  ^{EtOH}_{max} = 278 nm( epsilon  &#8764;20,000) [[Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257|{{RelationTable/GetFirstAuthor|Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257}}]]
|IR Spectra= 5.92, 6.09, 6.26, 10.3<FONT FACE="Symbol">m</FONT>m [[Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257|{{RelationTable/GetFirstAuthor|Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257}}]]
|IR Spectra= 5.92, 6.09, 6.26, 10.3 mu m [[Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257|{{RelationTable/GetFirstAuthor|Reference:Hamberg_M:Samuelsson_B:,J. Biol. Chem.,1966,241,257}}]]
|Source=The compound is contained in human seminal plasma in a considerable amount [[Reference:Bergstrom_S:,Science,1967,157,382|{{RelationTable/GetFirstAuthor|Reference:Bergstrom_S:,Science,1967,157,382}}]], but it is attributed presumably to a degradation product of 19-hydroxy-prostagaldnin E2 [[Reference:Taylor_PL:Kelly_RW:,Nature,1974,250,665|{{RelationTable/GetFirstAuthor|Reference:Taylor_PL:Kelly_RW:,Nature,1974,250,665}}]].
|Chemical Synthesis=
|Metabolism=
|Symbol=19-HYDROXY-PGB2
|Biological Activity=19-Hydroxy-prostaglandin B2 relaxes uterine myometriuim [[Reference:Horton_EW:,Physiol. Rev.,1969,49,122|{{RelationTable/GetFirstAuthor|Reference:Horton_EW:,Physiol. Rev.,1969,49,122}}]].
}}
}}
{{Lipid/Footer}}

Latest revision as of 09:01, 21 October 2010

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Upper classes: LB LBF



19-hydroxy Prostaglandin B2
LBF20307PG04.png
Structural Information
7- [2R- ((3S,7)-Dihydroxy-trans-1-octenyl) -5-oxo-1-cyclopenten-1R-yl] -cis-5-heptenoic acid
  • 19-hydroxy Prostaglandin B2
  • (15S,19)-Dihydroxy-9-oxo-5-cis-8(12),13-trans-prostadienoic acid
  • 7- [2R- ((3S,7)-Dihydroxy-1-(E)-octenyl) -5-oxo-1-cyclopenten-1R-yl] -5-(Z)-heptenoic acid
19-HYDROXY-PGB2
Formula C20H30O5
Exact Mass 350.20932407
Average Mass 350.4492
SMILES O[C@H](CCC[C@H](C)O)C=CC(=C1CC=CCCCC(O)=O)CCC(=O)1
Physicochemical Information
ETHANOL HambergMet al.
The compound is contained in human seminal plasma in a considerable amount Bergstrom_S , but it is attributed presumably to a degradation product of 19-hydroxy-prostagaldnin E2 Taylor_PL et al..
19-Hydroxy-prostaglandin B2 relaxes uterine myometriuim Horton_EW .
Spectral Information
Mass Spectra
UV Spectra λ EtOH
max
     = 278 nm( ε ∼20,000) HambergMet al.
IR Spectra 5.92, 6.09, 6.26, 10.3 μ m HambergMet al.
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20307PG04 See above. Bergstrom_S 1967
n.a. LBF20307PG04 See above. Hamberg_M et al. 1966
n.a. LBF20307PG04 See above. Horton_EW 1969
n.a. LBF20307PG04 See above. Taylor_PL et al. 1974