LBF20309HO01: Difference between revisions

No edit summary
No edit summary
Line 10: Line 10:
|Source=
|Source=
|Chemical Synthesis=
|Chemical Synthesis=
|Metabolism=Epoxide hydrolases convert the EpETrEs into vicinal diols[[Reference:Oliw_EH:Guengerich_FP:Oates_JA:,J. Biol. Chem.,1982,257,3771|{{RelationTable/GetFirstAuthor|Reference:Oliw_EH:Guengerich_FP:Oates_JA:,J. Biol. Chem.,1982,257,3771}}]];>, with the concurrent loss of much of their biological activity. (±)14,15-DiHETrE is the urinary metabolite of (±)14(15)-EpETrE which has been documented by GC/MS to be elevated in pregnancy induced hypertension [[Reference:Catella_F:Lawson_JA:Fitzgerald_DJ:FitzGerald_GA:,Proc. Natl. Acad. Sci. U. S. A.,1990,87,5893|{{RelationTable/GetFirstAuthor|Reference:Catella_F:Lawson_JA:Fitzgerald_DJ:FitzGerald_GA:,Proc. Natl. Acad. Sci. U. S. A.,1990,87,5893}}]];>.
|Metabolism=Epoxide hydrolases convert the EpETrEs into vicinal diols[[Reference:Oliw_EH:Guengerich_FP:Oates_JA:,J. Biol. Chem.,1982,257,3771|{{RelationTable/GetFirstAuthor|Reference:Oliw_EH:Guengerich_FP:Oates_JA:,J. Biol. Chem.,1982,257,3771}}]], with the concurrent loss of much of their biological activity. (±)14,15-DiHETrE is the urinary metabolite of (±)14(15)-EpETrE which has been documented by GC/MS to be elevated in pregnancy induced hypertension [[Reference:Catella_F:Lawson_JA:Fitzgerald_DJ:FitzGerald_GA:,Proc. Natl. Acad. Sci. U. S. A.,1990,87,5893|{{RelationTable/GetFirstAuthor|Reference:Catella_F:Lawson_JA:Fitzgerald_DJ:FitzGerald_GA:,Proc. Natl. Acad. Sci. U. S. A.,1990,87,5893}}]].
}}
}}


{{Lipid/Footer}}
{{Lipid/Footer}}

Revision as of 11:55, 25 November 2009

LipidBank Top
(トップ)
Fatty acid
(脂肪酸)
Glycerolipid
(グリセロ脂質)
Sphingolipid
(スフィンゴ脂質)
Journals
(雑誌一覧)
How to edit
(ページの書き方)


Upper classes: LB LBF



(+-) 14,15-dihydroxy-5Z,8Z,11Z-eicosatrienoic acid
LBF20309HO01.png
Structural Information
(+-) 14,15-dihydroxy-5Z,8Z,11Z-eicosatrienoic acid
  • (+-) 14,15-dihydroxy-5Z,8Z,11Z-eicosatrienoic acid
Formula C20H34O4
Exact Mass 338.24570957599997
Average Mass 338.48156
SMILES C(CCC(O)C(O)CC=CCC=CCC=CCCCC(O)=O)CC
Physicochemical Information
Epoxide hydrolases convert the EpETrEs into vicinal diols Oliw_EH et al., with the concurrent loss of much of their biological activity. (±)14,15-DiHETrE is the urinary metabolite of (±)14(15)-EpETrE which has been documented by GC/MS to be elevated in pregnancy induced hypertension Catella_F et al..
Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20309HO01 See above. Catella_F et al. 1990
n.a. LBF20309HO01 See above. Oliw_EH et al. 1982