LBF20406AM17: Difference between revisions

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|LipidBank=XPR7033
|LipidBank=XPR7033
|LipidMaps=LMFA08020019
|LipidMaps=LMFA08020019
|SysName=N- (1,1-dimethyl-2-hydroxyethyl) arachidonoyl amide
|SysName=N- (1,1-Dimethyl-2-hydroxyethyl) - (cis-5,cis-8,cis-11,cis-14) -eicosatetraenoylamine
|Common Name=&&N- (1,1-dimethyl-2-hydroxyethyl) arachidonoyl amide&&
|Common Name=&&N- (1,1-Dimethyl-2-hydroxyethyl) -arachidonoylamide&&N-  (1,1-Dimethyl-2-hydroxyethyl) -  (5Z,8Z,11Z,14Z) -eicosatetraenoylamine&&
|Melting Point=colorless oil [[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]]
|Melting Point=colorless oil [[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]]
|NMR Spectra=^1 H NMR (CDCl3)  delta 5.50 (br s, 1H), 5.28-5.40 (m,8H), 3.57 (s, 2H), 2.78-2.90 (m, 6H), 2.02-2.20 (m, 6H), 1.62-1.74 (m, 2H), 1.20-1.40 (m, 12H), 0.89 (t, J=7.1Hz, 3H). [[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]]
|NMR Spectra=^1 H NMR (CDCl3)  delta 5.50 (br s, 1H), 5.28-5.40 (m,8H), 3.57 (s, 2H), 2.78-2.90 (m, 6H), 2.02-2.20 (m, 6H), 1.62-1.74 (m, 2H), 1.20-1.40 (m, 12H), 0.89 (t, J=7.1Hz, 3H). [[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]]

Latest revision as of 04:43, 21 October 2010

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Upper classes: LB LBF



N- (1,1-Dimethyl-2-hydroxyethyl) -arachidonoylamide
LBF20406AM17.png
Structural Information
N- (1,1-Dimethyl-2-hydroxyethyl) - (cis-5,cis-8,cis-11,cis-14) -eicosatetraenoylamine
  • N- (1,1-Dimethyl-2-hydroxyethyl) -arachidonoylamide
  • N- (1,1-Dimethyl-2-hydroxyethyl) - (5Z,8Z,11Z,14Z) -eicosatetraenoylamine
Formula C24H41NO2
Exact Mass 375.313729561
Average Mass 375.58788
SMILES C(=CCCCC(=O)NC(CO)(C)C)CC=CCC=CCC=CCCCCC
Physicochemical Information
colorless oil Sheskin_T et al.
This compound was synthesized from arachidonoyl chloride and 2-amino-2-methyl-l-propanol.Yield 48 %. Sheskin_T et al.
Binding to the brain cannabinoid receptor (CBl), Ki(nM)= 161.8±34.1 Sheskin_T et al.
Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra 1H NMR (CDCl3) δ 5.50 (br s, 1H), 5.28-5.40 (m,8H), 3.57 (s, 2H), 2.78-2.90 (m, 6H), 2.02-2.20 (m, 6H), 1.62-1.74 (m, 2H), 1.20-1.40 (m, 12H), 0.89 (t, J=7.1Hz, 3H). SheskinTet al.
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20406AM17 See above. Sheskin_T et al. 1997