LBF20406AM32: Difference between revisions

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|Chemical Synthesis=This compound was synthesized from arachidonic acid and isopropylamine. Yield 85 %. [[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]]
|Chemical Synthesis=This compound was synthesized from arachidonic acid and isopropylamine. Yield 85 %. [[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]]
|Metabolism=
|Metabolism=
|Biological Activity=Binding to the brain cannabinoid receptor (CBl), Ki(nM)= 8.4±1.1 [[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]]
}}
}}


{{Lipid/Footer}}
{{Lipid/Footer}}

Revision as of 21:00, 6 January 2010

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(脂肪酸)
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Upper classes: LB LBF



N-isopropyl α-methyl arachidonoyl amide
LBF20406AM32.png
Structural Information
N-isopropyl α-methyl arachidonoyl amide
  • N-isopropyl α-methyl arachidonoyl amide
Formula C24H41NO
Exact Mass 359.318814939
Average Mass 359.58847999999995
SMILES N(C(C(C)CCC=CCC=CCC=CCC=CCCCCC)=O)C(C)C
Physicochemical Information
colorless oil Sheskin_T et al.
This compound was synthesized from arachidonic acid and isopropylamine. Yield 85 %. Sheskin_T et al.
Binding to the brain cannabinoid receptor (CBl), Ki(nM)= 8.4±1.1 Sheskin_T et al.
Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra 1H NMR (CDCl3) d5.30-5.42 (m, 8H), 4.02-4.14 (m, lH), 2.76-2.90 (m, 6H), 1.92-2.12 (m, 5H), 1.10-1.60 (series of m, 17H), 0.89 (t, J=6.9Hz, 3H). SheskinTet al.
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20406AM32 See above. Sheskin_T et al. 1997