LBF20406HO10: Difference between revisions

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|LipidBank=DFA8128
|LipidBank=DFA8128
|LipidMaps=LMFA03060024
|LipidMaps=LMFA03060024
|SysName=5R-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid
|SysName=5R-Hydroxy- (trans-6,cis-8,cis-11,cis-14) -eicosatetraenoic acid
|Common Name=&&5R-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid&&
|Common Name=&&5R-Hydroxy- (6E,8Z,11Z,14Z) -eicosatetraenoic acid&&
|UV Spectra=<FONT FACE="Symbol">l</FONT>max: 236nm <FONT FACE="Symbol">e</FONT>: 27,000
|UV Spectra= lambda max: 236nm epsilon : 27,000
|Source=5(R)-HETE is a monohydroxy polyunsaturated fatty acid produced by the nonenzymatic oxidation of arachidonic acid.
|Source=5(R)-HETE is a monohydroxy polyunsaturated fatty acid produced by the nonenzymatic oxidation of arachidonic acid.
|Chemical Synthesis=
|Chemical Synthesis=
|Metabolism=
|Metabolism=
|Symbol=5(R)-HETE
|Biological Activity=5(R)-HETE is a potent chemotactic agent. 5(R)-HETE induces human neutrophil migration across cellular and noncellular barriers in a dose- and time-dependent fashion, whereas 5(S)-HETE is inactive. [[Reference:Bittleman_DB:Casale_TB:,Am. J. Respir. Cell Mol. Biol.,1995,12,260|{{RelationTable/GetFirstAuthor|Reference:Bittleman_DB:Casale_TB:,Am. J. Respir. Cell Mol. Biol.,1995,12,260}}]].
}}
}}


{{Lipid/Footer}}
{{Lipid/Footer}}

Latest revision as of 07:25, 21 October 2010

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Upper classes: LB LBF



5R-Hydroxy- (6E,8Z,11Z,14Z) -eicosatetraenoic acid
LBF20406HO10.png
Structural Information
5R-Hydroxy- (trans-6,cis-8,cis-11,cis-14) -eicosatetraenoic acid
  • 5R-Hydroxy- (6E,8Z,11Z,14Z) -eicosatetraenoic acid
5(R)-HETE
Formula C20H32O3
Exact Mass 320.23514489
Average Mass 320.46628
SMILES C(CC=CCC=CCC=CC=C[C@@H](CCCC(O)=O)O)CCC
Physicochemical Information
5(R)-HETE is a monohydroxy polyunsaturated fatty acid produced by the nonenzymatic oxidation of arachidonic acid.
5(R)-HETE is a potent chemotactic agent. 5(R)-HETE induces human neutrophil migration across cellular and noncellular barriers in a dose- and time-dependent fashion, whereas 5(S)-HETE is inactive. Bittleman_DB et al..
Spectral Information
Mass Spectra
UV Spectra λ max: 236nm ε : 27,000
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20406HO10 See above. Bittleman_DB et al. 1995