LBF20406LT05: Difference between revisions

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{{Lipid/Header}}
{{Hierarchy|{{PAGENAME}}}}
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|LipidBank=XPR3114
|LipidBank=XPR3114
|LipidMaps=LMFA03020012
|LipidMaps=LMFA03020012
|SysName=N- (2-hydroxyethyl) -5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenamide
|SysName=N- (2-Hydroxyethyl) - (5S,12R) -dihydroxy- (cis-6,trans-8,trans-10,cis-14) -eicosatetraenamide
|Common Name=&&Leukotriene B4 Ethanolamide&&N- (2-hydroxyethyl) -5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenamide&&
|Common Name=&&Leukotriene B_4 ethanolamide&&N- (2-Hydroxyethyl) - (5S,12R) -dihydroxy- (6Z,8E,10E,14Z) -eicosatetraenamide&&
|Source=
|Chemical Synthesis=
|Metabolism=
|Biological Activity=LTB4-EA is reported as a potent antagonist about 3 fold higher affinity for the human LTB4 receptor that LTB4. And LTB4-EA antagonizes the LTB4-induced contractions of guinea pig lung parenchyma with 10 nM as an EC50.[[Reference:McHugh_D:McMaster_S:Ross_R:,13th_Annual_ICRS_Cannabinoid_Symposium,2003,,121|{{RelationTable/GetFirstAuthor|Reference:McHugh_D:McMaster_S:Ross_R:,13th_Annual_ICRS_Cannabinoid_Symposium,2003,,121}}]]
}}
}}
{{Lipid/Footer}}

Latest revision as of 07:51, 21 October 2010

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Upper classes: LB LBF



Leukotriene B4ethanolamide
LBF20406LT05.png
Structural Information
N- (2-Hydroxyethyl) - (5S,12R) -dihydroxy- (cis-6,trans-8,trans-10,cis-14) -eicosatetraenamide
  • Leukotriene B4ethanolamide
  • N- (2-Hydroxyethyl) - (5S,12R) -dihydroxy- (6Z,8E,10E,14Z) -eicosatetraenamide
Formula C22H37NO4
Exact Mass 379.27225867699997
Average Mass 379.53352
SMILES C(=CC[C@@H](O)C=CC=CC=C[C@H](CCCC(=O)NCCO)O)CCCCC
Physicochemical Information
LTB4-EA is reported as a potent antagonist about 3 fold higher affinity for the human LTB4 receptor that LTB4. And LTB4-EA antagonizes the LTB4-induced contractions of guinea pig lung parenchyma with 10 nM as an EC50. McHugh_D et al.
Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20406LT05 See above. McHugh_D et al. 2003