LBF20406LT12: Difference between revisions
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{{Lipid/Header}} | |||
{{Hierarchy|{{PAGENAME}}}} | {{Hierarchy|{{PAGENAME}}}} | ||
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|LipidBank=XPR3121 | |LipidBank=XPR3121 | ||
|LipidMaps=LMFA03020019 | |LipidMaps=LMFA03020019 | ||
|SysName=5S,12R- | |SysName=(5S,12R) -Dihydroxy-20,20,20-trifluoro- (cis-6,trans-8,trans-10,cis-14) -eicosatetraenoic acid | ||
|Common Name=&&20-trifluoro Leukotriene | |Common Name=&&20-trifluoro Leukotriene B_4&&(5S,12R) -Dihydroxy-20,20,20-trifluoro- (6Z,8E,10E,14Z) -eicosatetraenoic acid&& | ||
|Source= | |||
|Chemical Synthesis= | |||
|Metabolism= | |||
|Biological Activity=20-trifluoro LTB4 has equal chemotactic activity to LTB4 with an EC50 of 3 nM [[Reference:Tsai_BS:Keith_RH:Villani-Price_D:Haack_RA:Bauer_RF:Leonard_R:Abe_Y:Nicolaou_KC:,Prostaglandins,1989,37,287|{{RelationTable/GetFirstAuthor|Reference:Tsai_BS:Keith_RH:Villani-Price_D:Haack_RA:Bauer_RF:Leonard_R:Abe_Y:Nicolaou_KC:,Prostaglandins,1989,37,287}}]][[Reference:Nilsson_E:Gyllenhammar_H:Lerner_R:Palmblad_J:Ringertz_B:,Scand. J. Immunol.,1991,33,357|{{RelationTable/GetFirstAuthor|Reference:Nilsson_E:Gyllenhammar_H:Lerner_R:Palmblad_J:Ringertz_B:,Scand. J. Immunol.,1991,33,357}}]] but not degranulation activity of neutrophils.[[Reference:Tanaka_Y:Klauck_TM:Jubiz_W:Taguchi_T:Hanzawa_Y:Igarashi_A:Inazawa_K:Kobayashi_Y:Briggs_RG:,Arch. Biochem. Biophys.,1988,263,178|{{RelationTable/GetFirstAuthor|Reference:Tanaka_Y:Klauck_TM:Jubiz_W:Taguchi_T:Hanzawa_Y:Igarashi_A:Inazawa_K:Kobayashi_Y:Briggs_RG:,Arch. Biochem. Biophys.,1988,263,178}}]][[Reference:Tsai_BS:Keith_RH:Villani-Price_D:Haack_RA:Bauer_RF:Leonard_R:Abe_Y:Nicolaou_KC:,Prostaglandins,1989,37,287|{{RelationTable/GetFirstAuthor|Reference:Tsai_BS:Keith_RH:Villani-Price_D:Haack_RA:Bauer_RF:Leonard_R:Abe_Y:Nicolaou_KC:,Prostaglandins,1989,37,287}}]][[Reference:Nilsson_E:Gyllenhammar_H:Lerner_R:Palmblad_J:Ringertz_B:,Scand. J. Immunol.,1991,33,357|{{RelationTable/GetFirstAuthor|Reference:Nilsson_E:Gyllenhammar_H:Lerner_R:Palmblad_J:Ringertz_B:,Scand. J. Immunol.,1991,33,357}}]] | |||
}} | }} | ||
{{Lipid/Footer}} | |||
Latest revision as of 07:53, 21 October 2010
| LipidBank Top (トップ) |
Fatty acid (脂肪酸) |
Glycerolipid (グリセロ脂質) |
Sphingolipid (スフィンゴ脂質) |
Journals (雑誌一覧) |
How to edit (ページの書き方) |
| IDs and Links | |
|---|---|
| LipidBank | XPR3121 |
| LipidMaps | LMFA03020019 |
| CAS | |
| KEGG | {{{KEGG}}} |
| KNApSAcK | {{{KNApSAcK}}} |
| mol | LBF20406LT12 |
| 20-trifluoro Leukotriene B4 | |
|---|---|
| |
| Structural Information | |
| (5S,12R) -Dihydroxy-20,20,20-trifluoro- (cis-6,trans-8,trans-10,cis-14) -eicosatetraenoic acid | |
| |
| Formula | C20H29F3O4 |
| Exact Mass | 390.201794016 |
| Average Mass | 390.4370696 |
| SMILES | C(F)(F)(F)CCCCC=CC[C@H](C=CC=CC=C[C@H](CCCC(O)=O)O)O |
| Physicochemical Information | |
| 20-trifluoro LTB4 has equal chemotactic activity to LTB4 with an EC50 of 3 nM Tsai_BS et al. Nilsson_E et al. but not degranulation activity of neutrophils. Tanaka_Y et al. Tsai_BS et al. Nilsson_E et al. | |
| Spectral Information | |
| Mass Spectra | |
| UV Spectra | |
| IR Spectra | |
| NMR Spectra | |
| Other Spectra | |
| Chromatograms | |
| Reported Metabolites, References | ||||||||||||||||||||
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